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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antiplasmodial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(-)-CURINE IC50=353 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CYCLEAPELTINE IC50=0.03-0.04 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-DICENTRINE IC50=1260-2550 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ISOLAURELINE IC50=1610-2560 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-NOR-DICENTRINE IC50=470-1030 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ROEMEROLINE IC50=1,780-3,150 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-TETRAHYDROSTEPHABINE IC50=1,940-2,230 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-THAICANINE IC50=550-1,610 u/gml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-XYLOPINE IC50=440-2,270 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1,2-DI-O-ACETYLCORINE IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-BETA-HYDROPEROXYISOBILIN IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-DEACETYLKHIVORIN IC50=10 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-HYDROXYBENZOISOCHROMAN IC50=2.7 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-O-ACETYLNORPLUVIININE IC50=28.3-34.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
10'-HYDROXYUSAMBARENSINE IC50=0.2-0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
10,12-PEROXYCALAMENENE IC50=2.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
11-METHOXYAKUAMMICINE IC50=41.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
12-METHOXY-NB-METHYLVOACHOLATINE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
13-BETA-D-DIHYDROEURYCOMANOL IC50=0.5-2.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
14-HYDROXYCHAPARRINONE IC50=0.188 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Punica granatum Pomegranate; Grenadier (Fr.); Granatapfelbaum (Ger.); Granatapfelstrauch (Ger.); Zakuro (Jap.); Romanzeiro (Port.); Granado (Sp.); Mangrano (Sp.) 6 134, 400
Putoria calabrica 1 0
Pygeum acuminatum 1 0
Pyrus communis Pear 2 28
Quercus alba White Oak 1 0
Quercus bambusaefolia 1 3.700000047683716
Quercus championi 1 3.299999952316284
Quercus infectoria Aleppo Oak; Dyer's Oak; Gall Oak 2 0
Quercus myrsinaefolia 1 1.100000023841858
Quercus robur English Oak 1 0
Quercus rubra Northern Red Oak 1 0
Quercus suber Cork Oak 1 0
Quercus velutina Black Oak 1 0
Quisqualis indica Rangoon Creeper 1 0
Rauvolfia serpentina Indian Snakeroot; Serpentine Wood 1 0
Rauvolfia tetraphylla Four-Leaf Devilpepper; Pinque-Pinque 1 0
Rauvolfia vomitoria African Snakeroot 1 0
Rhododendron arboreum 1 0
Rhododendron dauricum Chinese Alpenrose 2 0
Rhododendron falconeri 1 0