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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antiplasmodial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
OLEANOLIC-ACID IC50=70-89 ug/ml *
OPHIOBOLIN-A IC50=0.5-0.6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OSUPUPINE IC50= 0.25ug/ml *
OXYACANTHINE IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PALMITINE-CHLORIDE IC50= 0.36ug/ml *
PATCHOULENE IC50=108 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHEANTHINE IC50=1,400 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PIPERINE Sabinsa: A series of well documented proprietary PR booklets,
e.g.Sabinsa Corps. 1998. Bronchial Asthma - Its etiology and control with traditional herbal extracts. Sabinsa Corporation. Piscataway, NJ. 49 pp.
PIQUEROL-A IC50=100 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLEIOCARPAMINE IC50=6-20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN IC50=0.178-0.189 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN IC50=0.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PRISTIMERIN IC50=0.19-28 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PSYCHOTRINE IC50=0.1-0.4 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PUNICALAGIN 1.5-8 ug/ml *
PUNICALAGIN IC50=7.5-8.8 uM *
QUERCETIN IC50=13-64 *
QUINDOLINE IC50=>229 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ROEMREFRIDINE IC50=0.6-0.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
RUBIADIN-1-METHYL-ETHER IC50=8-83 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Annona cherimola Cherimoya 1 0
Annona squamosa Sugar-Apple; Sweetsop 1 0
Anogeissus latifolia Gum Ghatti 2 0
Apium graveolens Celery 6 720, 500
Apocynum cannabinum Bitterroot; Spreading Dogbane 1 0
Arachis hypogaea Groundnut; Peanut 1 0
Aralia cordata Udo 1 0
Araucaria bidwillii Monkey puzzle 1 0
Arbutus menziesii 1 40, 000
Arbutus unedo Arbutus; Strawberry Tree 3 0
Arctium lappa Gobo; Great Burdock; Burdock 1 0
Arctostaphylos uva-ursi Bearberry; Uva Ursi 5 15, 909
Ardisia japonica Marlberry 1 0
Argemone mexicana Prickly Poppy 1 410
Armoracia rusticana Horseradish 1 0
Artemisia annua Qinghao; Sweet Annie; Annual Mugwort (GRIN); Annual Wormwood (GRIN); Sweet Wormwood (GRIN) 9 17, 325
Artemisia dracunculus Tarragon 1 0
Artemisia herba-alba Desert Wormwood 2 0
Artemisia indica 4 155
Artemisia salsoloides 3 10, 150