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Biological Activity Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Sort descending Dosage Reference
ARTEMISININ IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day) Duke, 1992 *
ARTEMISININ ED50=90 mg/kg orl mus Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTEMISININ ED95=1,000 mg/man/day Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTESUNATE not available Duke, 1992 *
ASCARIDOLE 0.05-0.1 uM Duke, 1992 *
ASIMICIN IC50=4 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ATALAPHILLININE 50 mg/kg/day ipr mus Duke, 1992 *
ATAPHILLININE 50 mg/kg (ipr mus) Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
AUGUSTINE IC50=0.14-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
AZADIRADIONE IC50=3 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
AZADIRONE IC50=12 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
BEBEERINE not available Merck 11th Edition
BENZOISOQUINOLONE-5-10-DIONE IC50=0.84 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BERBERASTINE 50 uM Duke, 1992 *
BERBERASTINE 0.14-0.36 ug/ml Duke, 1992 *
BERBERINE 0.14-0.36 ug/ml Duke, 1992 *
BERBERINE 50 uM Duke, 1992 *
BETA-DICHROINE not available Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
BETA-SELINENE IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BETA-SELININE-HYDROPEROXIDE 5.6 ug/ml Duke, 1992 *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Sort descending Common Name Chemical Count Total Parts Per Million
Vitex agnus-castus Chaste-Tree 5 4, 000.5
Vitis vinifera Grape; European Grape; Wine Grape; Grapevine; Vigne Vinifere (Fr.); Weinrebe (Ger.); Parra (Sp.); Vid (Sp.) 7 128
Wisteria floribunda not available 1 0
Withania somnifera Ashwagandha 2 0
Woodfordia floribunda not available 1 24.399999618530273
Wormia burbidgei not available 1 24, 000
Wormia triquetra not available 1 32, 000
Xanthorhiza simplicissima Yellowroot 5 26, 000
Xylopia aethiopica Ethiopian Pepper; Guinea Pepper; Negro Pepper; Spice Tree; Mohrenpfeffer (Ger.); Maniguete (Sp.); Pimienta de Guinea (Sp.) 1 0
Zanthoxylum alatum Indian Prickly Ash; Wartara Oil Tree 2 0
Zanthoxylum americanum Northern Prickly Ash 2 0
Zanthoxylum clava-herculis Pepperbark; Southern Prickly Ash; Hercules'-Club; West Indian Yellowwood 1 0
Zea mays Corn 2 0
Zingiber officinale Ginger 5 630
Ziziphus joazeiro not available 1 1, 200
Zizyphus jujuba Da-Zao; Jujube; Ta-Tsao 4 82, 704
Zizyphus mauritiana not available 1 60
Zizyphus nummularia not available 1 116.5999984741211
Zizyphus oenoplia not available 1 3, 266.800048828125
Zizyphus rugosa not available 1 644