An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. Antimalarial

Antimalarial

Download these results as:
CSV
EXCEL
PDF
List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
SECURININE 5.4 ug/ml *
SERGEOLIDE ED50=0.26 mg/kg day Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
SIMALIKALACTONE-D IC50=0.001-0.002 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SIPANDINOLIDE IC50=46 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SKIMMIANINE IC50=48.2 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
SUNGUCINE IC50=7.8-10.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SWERCHIN Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
TALCARPINE IC50=40.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TERMILIGNAN IC50=6-9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
THALIFABERIDINE IC50=0.12-0.88 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
THALIFABERINE IC50=0.44-5.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
THALIFASINE IC50=0.05-0.24 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TILIACORINE IC50=0.67 ug/ml *
TILIACORININE IC50=3.5 ug/ml *
TOMENTOSRIN IC50=7.8 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TOTAQUINE 600 mg/3x/day/man Martindale's 29th
TRANS-PINOCARVEOL IC50=5-50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TRANS-PINOCARVYL-HYDROPEROXIDE IC50=7.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TRICHIRUBRINE-A IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TRIGILLETIMINE IC50=22 ug/ml (ca 1/200 x chloroquine) *
Download these results as:
CSV
EXCEL
PDF
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Psidium cattleianum Strawberry Guava 2 0
Psidium guajava Guava 7 11, 210
Psophocarpus tetragonolobus Asparagus Pea; Goa Bean; Winged Bean 1 159, 000
Psychotria adenophylla 1 0
Pteridium aquilinum Bracken; Bracken Fern 2 0
Pterocarpus marsupium Indian Kino; Malabar Kino; bijasal 1 0
Pterocarpus santalinus Red Saunders 1 0
Ptychopetalum olacoides Muira Puama 1 0
Pueraria montana Kudzu; Kudsu 2 0
Punica granatum Pomegranate; Grenadier (Fr.); Granatapfelbaum (Ger.); Granatapfelstrauch (Ger.); Zakuro (Jap.); Romanzeiro (Port.); Granado (Sp.); Mangrano (Sp.) 7 123, 200
Putoria calabrica 1 0
Pygeum acuminatum 1 0
Pyrus communis Pear 3 28
Quercus alba White Oak 1 0
Quercus bambusaefolia 1 3.700000047683716
Quercus championi 1 3.299999952316284
Quercus infectoria Aleppo Oak; Dyer's Oak; Gall Oak 2 0
Quercus myrsinaefolia 1 1.100000023841858
Quercus robur English Oak 1 0
Quercus rubra Northern Red Oak 1 0