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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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ACE-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
OLEACEIN IC50=36 uM/ *
OLEACEIN IC50=26 uM/ *
OLEOSIDE 0.33 mg/ml (weak activity, 70% inhibition) *
OLEOSIDE-11-METHYL-ESTER 0.33 mg/ml (weak activity, 16% inhibition) *
OLEUROPEIN 0.33 mg/ml (weak activity, 8% inhibition) *
PEPSTATIN IC50@ug/ml *
PHENACEIN IC50=0.58 uM/ *
PROCYANIDIN-B-1 0.33 mg/ml (58.2% inhibition) *
PROCYANIDIN-B-2-3,3'-DI-O-GALLATE ED50=2.2 uM/ *
PROCYANIDIN-B-3 0.33 mg/ml (62.1% inhibition) *
PROCYANIDIN-B-3-3-O-GALLATE *
PROCYANIDIN-B-5-3,3'-DI-O-GALLATE ED50=1.3 uM/ *
PROCYANIDIN-B-6 0.17 mg/ml (36.7% inhibition) *
PROCYANIDIN-C-1-3,3',3''-TRI-O-GALLATE ED50=1.7 uM/ *
PROCYANIDIN-C-2 0.17 mg/ml (43.8% inhibition) *
PROCYANIDINS IC30-90=150-333 ug/ml *
PYCNOGENOL IC50=35 ug/ml hmn *
PYCNOGENOL 32 mg/kg ivn rat *
QUERCETIN-3-(2''-O-GALLOYL)-GLUCOSIDE ID50=300 ug/ml rat (24 hr.) *
QUERCETIN-3-O-(2''-O-GALLOYL)-GLUCOSIDE IC50=2.7 mM/l *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Carum carvi Caraway; Carum; Kummel (Ger.); Comino (Sp.); Comino de prado (Sp.) 8 169, 720
Carya glabra Pignut Hickory 1 1, 100
Carya illinoensis Pecan 1 56
Carya ovata Shagbark Hickory 1 388
Cassia tora Sickle Senna 1 31
Castanea dentata American Chestnut 1 24
Castanea mollisima Chinese Chestnut 1 17
Castanea sativa European Chestnut 3 10
Catalpa ovata Hsin-Pa-Pi; Kisasage 1 42
Caulophyllum thalictroides Blue Cohosh 1 0
Ceiba pentandra Kapok; Silk-Cotton Tree 1 0
Celosia cristata Cockscomb 1 39
Centaurea calcitrapa Star-Thistle 1 0
Centella asiatica Gotu Kola; Pennywort 6 20, 013.60000038147
Ceratonia siliqua Carob; St.John's-Bread; Locust Bean 3 0
Chaenomeles lagenaria Chinese Quince; Mu-Kua 1 42
Chamaemelum nobile Garden Camomile; Perennial Camomile; Roman Camomile 3 0
Chamaesyce hypericifolia Spurge 1 0
Chamissoa altissima Guanique 1 36
Chenopodium album Lambsquarter 1 24