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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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ACE-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
OLEACEIN IC50=26 uM/ *
OLEACEIN IC50=36 uM/ *
OLEOSIDE 0.33 mg/ml (weak activity, 70% inhibition) *
OLEOSIDE-11-METHYL-ESTER 0.33 mg/ml (weak activity, 16% inhibition) *
OLEUROPEIN 0.33 mg/ml (weak activity, 8% inhibition) *
PEPSTATIN IC50@ug/ml *
PHENACEIN IC50=0.58 uM/ *
PROCYANIDIN-B-1 0.33 mg/ml (58.2% inhibition) *
PROCYANIDIN-B-2-3,3'-DI-O-GALLATE ED50=2.2 uM/ *
PROCYANIDIN-B-3 0.33 mg/ml (62.1% inhibition) *
PROCYANIDIN-B-3-3-O-GALLATE *
PROCYANIDIN-B-5-3,3'-DI-O-GALLATE ED50=1.3 uM/ *
PROCYANIDIN-B-6 0.17 mg/ml (36.7% inhibition) *
PROCYANIDIN-C-1-3,3',3''-TRI-O-GALLATE ED50=1.7 uM/ *
PROCYANIDIN-C-2 0.17 mg/ml (43.8% inhibition) *
PROCYANIDINS IC30-90=150-333 ug/ml *
PYCNOGENOL IC50=35 ug/ml hmn *
PYCNOGENOL 32 mg/kg ivn rat *
QUERCETIN-3-(2''-O-GALLOYL)-GLUCOSIDE ID50=300 ug/ml rat (24 hr.) *
QUERCETIN-3-O-(2''-O-GALLOYL)-GLUCOSIDE IC50=2.7 mM/l *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Rosa spp Rose Hips 1 0
Rosmarinus eriocalyx Rosemary 4 1, 645
Rosmarinus officinalis Rosemary 5 420, 029
Rosmarinus tomentosus Hairy Rosemary 4 290
Rosmarinus x lavandulaceus Lavender Rosemary 4 1, 270
Rosmarinus x mendizabalii Mendizabali's Rosemary 4 445
Rubia cordifolia Madder 1 39
Rubus chamaemorus Cloudberry 1 40
Rubus chingii Chinese Raspberry 1 28
Rubus idaeus Red Raspberry; Raspberry 6 174
Rumex acetosa Garden Sorrel 2 20
Rumex crispus Curly Dock; Lengua De Vaca; Yellow Dock; Sour Dock 4 0
Ruscus aculeatus Butcher's Broom; Box-Holly 4 4.199999809265137
Salix alba White Willow 6 122.09999990463257
Salvia canariensis Canary Island Sage 3 0.30000000447034836
Salvia dorisiana 'Honduran' Sage 4 45.50000047683716
Salvia gilliesii 'Cordoba' Sage 2 36.5
Salvia miltiorrhiza Dan-Shen; Red Sage; Tan-Shen 1 36
Salvia officinalis Sage 7 61, 447.90000009537
Salvia sclarea Clary Sage 3 218