Biological Activity 5-Lipoxygenase-Inhibitor | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
ESCULETIN	IC50=0.1-5 uM	Duke, 1992 *
FISETIN	IC50 (uM)=11	Duke, 1992 *
GAMMA-BOSWELLIC-ACID	not available	Duke, 1992 *
KAEMPFEROL	IC50 (uM)=20	Duke, 1992 *
MYRCETIN	IC50 (uM)=13	Duke, 1992 *
N-PROPYLSULPHINOTHIOIC-ACID-S-N-PROPYLESTER	not available	Duke, 1992 *
NDGA	IC50 (uM)=0.8	Duke, 1992 *
NORDIHYDROGUAIARETIC-ACID	not available	Duke, 1992 *
OSTHOL	not available	Duke, 1992 *
PARTHENOLIDE	not available	Duke, 1992 *
PROPYL-GALLATE	IC50 (uM)=5	Duke, 1992 *
QUERCETIN	IC50 (uM)=4	Duke, 1992 *
RESVERATROL	IC50=1-9 uM	Duke, 1992 *
RESVERATROL	IC50=48 uM	Duke, 1992 *
SANGUINARINE	not available	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
SHOGAOL	not available	Duke, 1992 *
TRANS-5-ETHYL-4,6,7-TRITHIA-2-DECENE-4-S-OXIDE	not available	Duke, 1992 *
TRANS-METHYLSULPHINOTHIOIC-ACID-S-1-PROPENYLESTER	not available	Duke, 1992 *
TRANS-N-PROPYLSULPHINOTHIOIC-ACID-S-1-PROPENYLESTER	not available	Duke, 1992 *
TRANS-TRANS-5-ETHYL-4,6,7-TRITHIA-2,8-DECADIENE-4-S-OXIDE	not available	Duke, 1992 *

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Curcuma zedoaria	Shoti; Zedoary	1	2, 000
Cuscuta reflexa	Amarbel	1	0
Cyamopsis tetragonoloba	Guar; Cluster-Bean; Siam-Bean	2	0
Cymbopogon citratus	West Indian Lemongrass; Lemongrass	1	0
Cynara cardunculus	Artichoke	1	0
Cytisus scoparius	Scotch Broom	2	0
Datura stramonium	Jimsonweed	1	0
Daucus carota	Carrot	3	0
Diospyros virginiana	American Persimmon	2	0
Dodonaea viscosa	Hopwood	2	0
Drimys winteri	Winter's Bark	2	0
Echinacea angustifolia	Echinacea; Narrow Leaf Echinacea; Narrow Leaf Purple-Coneflower	2	0
Echinacea purpurea	Echinacea; Eastern Purple-Coneflower; Purple-Coneflower	1	0
Echinacea spp	Coneflower; Echinacea	2	0
Elaeagnus angustifolia	Russian Olive; Silver Berry	2	0
Ephedra sinica	Ma Huang; Chinese Ephedra	2	0
Equisetum arvense	Field Horsetail; Horsetail	2	0
Eriobotrya japonica	Loquat	2	0
Erythroxylum coca	Coca	1	0
Eschscholzia californica	California Poppy	2	160