Plant Holarrhena pubescens (Apocynaceae) | Dr. Duke's Phytochemical and Ethnobotanical Databases

Common Names

Tellicherry Bark; Zhi Xie Mu; Conessi; Kurchi

How this plant is used

Medicinal

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List of plant chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Activity Count	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
N-N'-TETRAMETHYLHOLARRHIMINE	0	Stem Bark	not available	not available	not available	Duke, 1992 *
N-N-1-TETRAMETHYLHOLARRHIMINE	0	Plant	not available	not available	not available	Duke, 1992 *
NORCONESSINE	1	Bark	not available	3.0	not available	Duke, 1992 *
NORHOLADIENE	0	Bark	not available	1.2	not available	Begum, S., Usmani, S. B., Siddiqui, B. S., Siddiqui, S. 1994. Alkaloids from the Bark of Holarrhena pubescens. Phpytochemistry, 36(6): 1537-1541.
OLEIC-ACID	18	Seed	39900.0	63000.0	-0.46	Duke, 1992 *
PALMITIC-ACID	13	Seed	10640.0	16800.0	-0.35	Duke, 1992 *
PUBESCIMINE	0	Bark	not available	3.2	not available	Begum, S., Usmani, S. B., Siddiqui, B. S., Siddiqui, S. 1994. Alkaloids from the Bark of Holarrhena pubescens. Phpytochemistry, 36(6): 1537-1541.
PUBESCINE	0	Bark	not available	2.5	not available	Begum, S., Usmani, S. B., Siddiqui, B. S., Siddiqui, S. 1994. Alkaloids from the Bark of Holarrhena pubescens. Phpytochemistry, 36(6): 1537-1541.
PUBESCININE	0	Bark	not available	1.8	not available	Siddiqui, B. S., Usmani, S. B., Begum, S., Siddiqui, S., Aftab, K., Gilani, A. U. 1995. Hypotensive Constituents from the Bark of Holarrhena pubescens (Holarrhena antidysenterica). Heterocycles, 41(2): 267-276.
QUERCETIN	176	Leaf	not available	not available	not available	Duke, 1992 *
REGHOLARRHENINE-A	0	Bark	not available	3.6	not available	Duke, 1992 *
REGHOLARRHENINE-A	0	Stem Bark	not available	110.0	not available	Duke, 1992 *
REGHOLARRHENINE-B	0	Stem Bark	not available	166.0	not available	Duke, 1992 *
REGHOLARRHENINE-C	0	Stem Bark	not available	70.0	not available	Duke, 1992 *
REGHOLARRHENINE-D	0	Stem Bark	not available	15.0	not available	Duke, 1992 *
REGHOLARRHENINE-E	0	Stem Bark	not available	15.5	not available	Duke, 1992 *
REGHOLARRHENINE-F	0	Stem Bark	not available	400.0	not available	Duke, 1992 *
RESIN	0	Bark	not available	2000.0	-1.04	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
STEARIC-ACID	8	Seed	not available	12920.0	-0.29	Duke, 1992 *
STIGMASTADIENOL	0	Bark	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.

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List of plant activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Chemical Count	Reference
Antiaggregant	2	Duke, 1992 *
Antiaging	1	Duke, 1992 *
Antiallergic	2	Duke, 1992 *
Antialopecic	3	Duke, 1992 *
Antialzheimeran	2	Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Antianaphylactic	2	Economic & Medicinal Plant Research, 6: 189.
Antiandrogenic	4	Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiangiogenic	2	Duke, 1992 *
Antiarrhythmic	1	Duke, 1992 *
Antiarteriosclerotic	1	Duke, 1992 *
Antiarthritic	3	Economic & Medicinal Plant Research, 6: 189.
Antiasthmatic	1	Duke, 1992 *
Antiatherosclerotic	1	Duke, 1992 *
Antibacterial	6	Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer	4	Duke, 1992 *
Anticancer (Breast)	1	Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)	1	Duke, 1992 *
Anticancer (Colon)	1	Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticancer (Lung)	1	Duke, 1992 *
Anticarcinomic	1	Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.