Senna alata | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Ringworm Bush

How used

Medicinal

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Activities: 131

Chemicals w/Activities: 7

All Chemicals: 14

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Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	1,3,8-TRIHYDROXY-2-METHYL-ANTHRAQUINONE	Root	--	--	--	*
0	1,5-DIHYDROXY-8-METHOXY-2-METHYL-ANTHRAQUINONE...GLUCOPYRANOSIDE	Plant	--	--	--	*
24	ALOE-EMODIN	Plant	--	--	--	*
Antibacterial MIC=2-64 ug/ml * Antiherpetic * Antileukemic * Antisalmonella Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiseptic MIC=2-64 ug/ml * Antistaphylococcic MIC=2-64 ug/ml * Antitumor 1 ug/mL * Antiviral * Arylamine-N-Acetyltransferase-Inhibitor * Calcium-Antagonist (strong activity) * Candidicide MIC=25-250 ug/ml * Cathartic Merck 11th Edition Cytotoxic 20 ppm * Estrogenic * Fungicide MIC=25-250 ug/ml * Genotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Laxative * Mutagenic * Pesticide * Purgative ED50=>59.6 mg/kg orl mus * Termitifuge Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Topoisomerase-II-Inhibitor 1 mM Muller, S. O., Eckert, I., Lutz, W. K., Stopper, H. 1996. Genotoxicity of the Laxative Drug Components Emodin, Aloe-emodin and Danthron in Mammalian Cells: Topoisomerase II Mediated? Mutat Res, 371: 165-173. Topoisomerase-II-Inhibitor IC50=741 uM/ml Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414. Tuberculostatic Pakistan Encyclopedia Planta Medica. 1986.
47	BETA-SITOSTEROL	Root	--	--	--	*
Androgenic * Angiogenic * Anorexic Martindale's 28th Antiadenomic Merck 11th Edition Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Anticancer (Cervix) * Anticancer (Lung) * Antiedemic IC54=320 mg/kg orl * Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * Antileukemic * Antilymphomic * Antimutagenic 250 ug/ml * Antiophidic 2.3 mg mus Economic & Medicinal Plant Research, 5: 363. Antioxidant IC44=10 uM * Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antiprostaglandin 30 mg/day/12 wks * Antiprostatadenomic Merck 11th Edition Antiprostatitic 10-20 mg 3 x/day/orl man * Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Antitumor (Cervix) * Antitumor (Lung) * Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991. Apoptotic * Artemicide LC50=110 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Caspase-8-Inducer * Estrogenic * Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Hepatoprotective * Hypocholesterolemic 2-6 g/man/day/orl Martindale's 30th Hypocholesterolemic 9-3,330 mg/man/day/orl Martindale's 28th Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypolipidemic 2-6 g/day * Pesticide * Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Ulcerogenic 500 mg/kg ipr rat *
10	CHRYSAROBIN	Leaf	--	--	--	*
Allergenic Merck 11th Edition Antipsoriac Martindale's 29th Antitrichophytotic * Cytotoxic 1 ug/mL De Smet, P.A.G.M., Keller, K., Hansel, R. and Chandler, R.F., eds. 1993. Adverse Effects of Herbal Drugs 2. Springr-Verlag, Berlin. 348pp. Emetic * Fungicide Merck 11th Edition Irritant * Keratolytic * Mutagenic De Smet, P.A.G.M., Keller, K., Hansel, R. and Chandler, R.F., eds. 1993. Adverse Effects of Herbal Drugs 2. Springr-Verlag, Berlin. 348pp. Pesticide *
10	CHRYSOPHANOL	Plant	--	--	--	*
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Antiseptic * Calcium-Antagonist 5/6 aloeemodin * Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Cathartic * Hemostat * Pesticide * Pigment Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Purgative ED50=>500 mg/kg orl mus * Termitifuge Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	CHRYSOPHANOL-GLYCOSIDE	Leaf	--	--	--	*
0	DIHYDROXYMETHYLANTHRAQUINONE	Leaf	--	--	--	*
58	EMODIN	Plant	--	--	--	*
AGEs-Inhibitor IC50=118 uM * Aldose-Reductase-Inhibitor IC50=15.9 uM * Allergenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiaggregant * Antiangiogenic * Antibacterial * Anticytomegalovirus ED50=1.1 ug/ml * Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antiinflammatory 15 mg/kg * Antileukemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antilymphomic * AntiMRSA MIC 2-64 ug/ml * Antimutagenic * Antineoplastic * Antiplaque ED50=1.1 ug/ml * Antiproliferant IC50=20-30 uM * Antisarcomic * Antiseptic * Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antisprout * Antitumor (Breast) * Antiulcer 15 mg/kg * Antivaginitic TIllotson, A. K. (with Abel, Jr., R., Tillotson, N.H., Bajracharya, V.M.B.). 2001. The One Earth Herbal Sourcebook: Everything You Need to Know about Chinese, Western, and Ayurvedic Herbal Treatments. Twin Streams, Kensington Publishing Corp. NY,NY. 596 pp Antiviral ED50=1.1 ug/ml * Antiviral EC50=1.1 * Cathartic Merck 11th Edition CNS-Depressant 15 mg/kg ipr mus * Collagenase-Inhibitor IC50=40 uM * COX-2-Inhibitor * Cytotoxic CD50=2.6 ug/ml * Differentiator IC50=20-30 uM * Estrogenic * Genotoxic * Gonadotropic * Hypolipidemic * Immunostimulant * Immunosuppressant * iNOS-Inhibitor * Leucocytogenic * MMP-2-Inhibitor * MMP-7-Inhibitor * MMP-9-Inhibitor * Mutagenic * NO-Inhibitor IC50=60.7 uM * Pesticide * PGE2-Inhibitor * Prostaglandin-Synthesis-Inhibitor IC50=23 uM/ml Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414. Protein-Kinase-C-Inhibitor IC50=25 uM * PTK-Inhibitor 10-100 uM * PTK-Inhibitor IC50=19-37 uM * Purgative ED50=>500 mg/kg orl mus * Styptic * Topoisomerase-II-Inhibitor 1 mM Muller, S. O., Eckert, I., Lutz, W. K., Stopper, H. 1996. Genotoxicity of the Laxative Drug Components Emodin, Aloe-emodin and Danthron in Mammalian Cells: Topoisomerase II Mediated? Mutat Res, 371: 165-173. Topoisomerase-II-Inhibitor IC50=7 uM/ml Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414. Trichomonicide * Tyrosine-Kinase-Inhibitor * Vasodilator * Vasorelaxant *
0	FAT	Seed	29000.0	35000.0	-1.21	*
0	PROTEIN	Seed	161000.0	181000.0	-0.47	*
18	RHEIN	Plant	--	--	--	*
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Anticarcinomic * Anticariogenic * Anticytomegalovirus ED50=1.1 ug/ml * Antineoplastic * Antiplaque ED50=0.6 ug/ml * Antiseptic * Antitumor * Antiviral EC50=1.1 * Antiviral ED50=0.61 ug/ml * Calcium-Antagonist 9/10 aloeemodin * Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Cathartic * Cytotoxic CD50=3.4 ug/ml * Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Proteinase-Inhibitor * Purgative ED50=97.5 mg/kg orl mus *
0	RHEIN-GLYCOSIDE	Leaf	--	--	--	*
35	TANNIN	Leaf	--	--	--	*
Anthelmintic * Antibacterial * Anticancer * Anticariogenic * Antidiarrheic * Antidysenteric * Antihepatotoxic * AntiHIV * Antihypertensive * Antilipolytic * Antimutagenic * Antinephritic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antiophidic Economic & Medicinal Plant Research, 5: 363. Antioxidant 1/3 quercetin * Antioxidant IC50=1.44 ug/ml * Antiradicular 1/3 quercetin * Antiradicular 500 mg/kg/day orl mus Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antirenitic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antitumor * Antitumor-Promoter * Antiulcer * Antiviral * Cancer-Preventive HerbalGram No. 22 - Spring 1990, page 14. Carcinogenic * Chelator * Cyclooxygenase-Inhibitor * Glucosyl-Transferase-Inhibitor * Hepatoprotective * Immunosuppressant * Lipoxygenase-Inhibitor * MAO-Inhibitor * Ornithine-Decarboxylase-Inhibitor * Pesticide * Psychotropic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Xanthine-Oxidase-Inhibitor *

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Senna alata (Fabaceae)

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