An official website of the United States government.
Plant Rhododendron ponticum (Ericaceae)
Download a full report in PDF format
Common name(s)
Pontic Alpenrose
How used
Medicinal
Data Views
| # Activity | Chemical Name | Part | Low PPM | High PPM | StdDev | *Reference |
|---|---|---|---|---|---|---|
| 30 | (+)-CATECHIN | Leaf | -- | -- | -- | * |
|
ACE-Inhibitor IC50=0.155 mM/l
*
ACE-Inhibitor 0.24 mg/ml rbt (weak activity)
*
Antiaggregant IC68=200 ug/ml
*
Anticoagulant
*
Anticomplementary 1/2 aspirin
*
AntiHIV EC50=4 ug/ml
*
Antiinflammatory IC50=40-943 uM (cf indomethacin IC50=1 uM)
*
Antimutagenic ID50=50-100 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant
*
Antiperoxidant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiprostaglandin IC50=40-943 uM (cf indomethacin IC50=1 uM)
*
Antiradicular
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiulcer
*
Beta-Adrenergic Receptor Blocker 10 uM (weak activity)
Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447.
cAMP-Phosphodiesterase-Inhibitor
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic
*
COX-1-Inhibitor IC50=183-279 uM (cf indomethacin IC50=1 uM)
*
COX-2-Inhibitor IC50=546-5,910 uM (cf indomethacin IC50=1 uM)
*
Cyclooxygenase-Inhibitor
*
Cytotoxic TC50=>100 ug/ml
*
Dermatitigenic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hemostat
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hepatoprotective
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunostimulant
Economic & Medicinal Plant Research, 1: 124.
Neuroprotective 1-10 uM
*
NO-Inhibitor IC11=250 uM
*
Phagocytotic
Economic & Medicinal Plant Research, 1: 124.
Vasoconstrictor
Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
Xanthine-Oxidase-Inhibitor
Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
|
||||||
| 7 | (+)-GALLOCATECHIN | Leaf | -- | -- | -- | * |
|
ACE-Inhibitor
*
Antimutagenic
*
Antinociceptive
*
Antioxidant
*
Antithyrotoxic
Wealth of India.
Bactericide MIC 250 ug/ml
Wealth of India.
Beta-Adrenergic Receptor Blocker 10 uM
Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447.
|
||||||
| 38 | (-)-EPICATECHIN | Leaf | -- | -- | -- | * |
|
5-Lipoxygenase-Inhibitor IC50=22-50 uM/l
*
ACE-Inhibitor IC50=0.216 mM/l
*
ACE-Inhibitor 0.5 mg/ml rbt (weak activity)
*
Allelochemic
Hanke, F. J., Natural Products as a Resource for Biologically Active Compounds, Thesis, U. Cal (Santa Cruz), 1986, 252 pp
Antiaggregant
*
Antianaphylactic
*
Antibacterial
*
Antidiabetic 30 mg/kg rat
*
AntiEBV
Economic & Medicinal Plant Research, 6: 189.
Antihepatitic
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
AntiHIV EC50=2 ug/ml
*
Antihyperglycemic
*
Antiinflammatory
*
Antileukemic
Economic & Medicinal Plant Research, 6: 189.
Antileukotriene
*
Antilipoperoxidant
*
Antimutagenic
*
Antioxidant IC50=6.3 ug/ml
*
Antiperoxidant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral EC50=2 ug/ml
*
Beta-Adrenergic Receptor Blocker 10 uM
Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic
*
Choline-Sparing
*
COMP-Inhibitor
Dullo, A. G., et al. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am. J. Clinical Nutrition, 70: 1040-1045.
Cytotoxic TC50=>100 ug/ml
*
Hypocholesterolemic
*
Hypoglycemic
*
Immunostimulant
*
Insulinogenic
Economic & Medicinal Plant Research, 6: 170.
Lipoxygenase-1-Inhibitor IC50=60 mM
*
Lipoxygenase-Inhibitor IC50=140 uM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Lipoxygenase-Inhibitor IC97=5 mM
Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Pancreatogenic
*
Pesticide
*
Reverse-Transcriptase-Inhibitor 10 ng/ml
McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Vasodilator uM
McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Xanthine-Oxidase-Inhibitor IC50=>40
Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
|
||||||
| 0 | ACETYLANDROMEDIENOL | Leaf | -- | -- | -- | * |
| 1 | ACETYLANDROMEDOL | Leaf | -- | -- | -- | * |
|
Hypotensive 5-10 ug/kg ivn dog
Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
|
||||||
| 10 | ALPHA-AMYRIN | Plant | -- | -- | -- | * |
|
Analgesic
*
Antiedemic IC43=40 mg/kg ipr rat
*
Antiinflammatory IC71=1,000 ppm orl
*
Antinociceptive
*
Antitumor
*
Antiulcer
*
Cytotoxic 50-400
*
Gastroprotective
*
Hepatoprotective
*
Insectifuge
*
|
||||||
| 0 | ANDROMEDOL | Leaf | -- | -- | -- | * |
| 0 | ANDROMEDOLDITERPENES | Leaf | -- | -- | -- | * |
| 15 | ARBUTIN | Plant | -- | -- | -- | * |
|
Allelochemic IC51=1.1 mM
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antibacterial MIC=4,000-8,000 ppm
*
Antiedemic 50 mg/kg
*
Antimelanogenic IC50=40 uM
*
Antiseptic 60-200 mg/man
*
Antistreptococcic MIC=4,000-8,000 ppm
Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antitussive
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Artemicide
Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Candidicide
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Diuretic 60-200 mg/man
Merck 11th Edition
Insulin-Sparing
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Mycoplasmistat
Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Pesticide
*
Tyrosinase-Inhibitor IC50=40 uM
*
Urinary-Antiseptic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
|
||||||
| 47 | BETA-SITOSTEROL | Plant | -- | -- | -- | * |
|
Androgenic
*
Angiogenic
*
Anorexic
Martindale's 28th
Antiadenomic
Merck 11th Edition
Antiandrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
*
Anticancer (Lung)
*
Antiedemic IC54=320 mg/kg orl
*
Antiestrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
*
Antileukemic
*
Antilymphomic
*
Antimutagenic 250 ug/ml
*
Antiophidic 2.3 mg mus
Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
*
Antiprogestational
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
*
Antiprostatadenomic
Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
*
Antipyretic
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
*
Antitumor (Lung)
*
Antiviral
Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
*
Artemicide LC50=110 ppm
Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
*
Estrogenic
*
Febrifuge
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
*
Hypocholesterolemic 2-6 g/man/day/orl
Martindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orl
Martindale's 28th
Hypoglycemic
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
*
Pesticide
*
Spermicide
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
*
|
||||||
| 102 | CAFFEIC-ACID | Plant | -- | -- | -- | * |
|
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)
Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allergenic
*
Analgesic
*
Antiadenoviral
Economic & Medicinal Plant Research, 5: 207.
Antiaggregant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiaging
*
Antiatherogenic
*
Antibacterial
*
Anticancer
*
Anticarcinogenic
Economic & Medicinal Plant Research, 6: 189.
Antidepressant
*
Antiedemic
Economic & Medicinal Plant Research, 6: 189.
Antielastase IC50=86 ug/ml (475 uM)
*
Antielastase IC50=93 um/l
*
Antiescherichic
*
Antiflu
Economic & Medicinal Plant Research, 5: 207.
Antigonadotropic
Jim Duke's personal files.
Antihemolytic 25 uM
Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antihepatoadenomic 200 ppm diet orl mus
*
Antihepatotoxic
*
Antiherpetic EC50=>50 ug/ml
*
Antiherpetic 50 ug/ml
*
Antihistaminic
*
AntiHIV EC50=200 ug/ml
*
Antihypercholesterolemic
Economic & Medicinal Plant Research, 6: 189.
Antihyperthyroid
*
Antiinflammatory
*
AntiLegionella
*
Antileukemic
Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene
*
Antimelanogenic
*
Antimutagenic
Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antinitrosaminic
Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antiophidic
*
Antioxidant 50 uM
*
Antioxidant 30 mM
*
Antioxidant 1.3 x Vit. E
*
Antioxidant 1/3 quercetin
*
Antioxidant 1/2 BHA
*
Antioxidant IC57=30 ppm
*
Antiperoxidant IC50=44 uM
Planta Medica, 57: A54, 1991.
Antiperoxidant IC85=100 ug/ml
*
Antiperoxidant IC35=200 ug/ml
*
Antiproliferant
Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiprostaglandin
*
Antiradicular 10 uM
Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antiradicular 30 mM
*
Antiradicular 1/3 quercetin
*
Antiradicular IC50=32-35 uM
*
Antiseptic
*
Antispasmodic EC50=3.4-15 uM
Phytotherapy Research, 4: 73.
Antistaphylococcic
*
Antistomatitic
Economic & Medicinal Plant Research, 5: 207.
Antisunburn
*
Antithiamin
Phenolic Compounds in Food and Their Effects on Health, 69.
Antithyroid
Jim Duke's personal files.
Antitumor 200 ppm diet orl mus
*
Antitumor (Skin)
*
Antitumor-Promoter IC42=10 uM
Cancer Research, 48: 5941.
Antiulcerogenic
*
Antivaccinia
Economic & Medicinal Plant Research, 5: 207.
Antiviral IC50=62.5 ug/ml
*
Anxiolytic
*
Calcium-Antagonist IC50=1.2 uM rbt
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic 2% (diet)
*
Chemopreventive
*
Cholagogue
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Clastogenic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
CNS-Active
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Co-carcinogenic
*
Collagen-Sparing
*
COX-2-Inhibitor IC32=100 uM
*
Cytoprotective
Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Cytotoxic TC50=200 ug/ml
*
Diuretic
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
DNA-Active
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DNA-Protective
*
Fungicide MIC=0.4 mg/ml
*
Hepatocarcinogenic 400 ppm diet orl mus (in the absence of alcohol)
*
Hepatoprotective
Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 210.
Hepatotropic
*
Histamine-Inhibitor
*
Immunostimulant
*
Insectifuge
Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Leukotriene-Inhibitor
*
Lipoxygenase-Inhibitor IC50=62-148 uM
*
Lipoxygenase-Inhibitor IC27=5 mM
Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lyase-Inhibitor IC50=94-164 uM
*
Metal-Chelator
McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor
Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Pesticide
*
Prooxidant
*
Prostaglandigenic
*
Sedative 500 mg
*
Sunscreen IC50=2.5 mg/l
Lazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC91=5 mg/l
Lazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC98=25 mg/l
Lazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Tumorigenic
Jim Duke's personal files.
Vulnerary
*
Xanthine-Oxidase-Inhibitor IC50=39.21 uM
Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
|
||||||
| 77 | CHLOROGENIC-ACID | Plant | -- | -- | -- | * |
|
Aldose-Reductase-Inhibitor IC50=1.8 uM rat (strong activity)
Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345.
Allelochemic
*
Allergenic
*
Analgesic
*
Antiatherosclerotic
*
Antibacterial
*
Anticancer (Colon)
*
Anticancer (Forestomach)
*
Anticancer (Liver)
*
Anticancer (Skin)
*
Anticarcinogenic
*
Antidiabetic
*
AntiEBV
Economic & Medicinal Plant Research, 6: 189.
Antifeedant
*
Antigenotoxic
*
Antigonadotropic
Jim Duke's personal files.
Antihemolytic 10 uM
Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antihepatotoxic
*
Antiherpetic
Economic & Medicinal Plant Research, 5: 194.
Antihistaminic
*
AntiHIV
Economic & Medicinal Plant Research, 6: 189.
Antihypercholesterolemic
Economic & Medicinal Plant Research, 6: 189.
Antihyperthyroid
*
Antiinflammatory
Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
AntiLegionella
*
Antileukotriene
*
Antimelanogenic
*
Antimutagenic
*
Antinitrosaminic
*
Antioxidant IC53=200 ppm
Huang, M-T., and Ferraro, T. Phenolic Compounds in Food and Cancer Prevention. Phenolic Compounds in Food and Their Effects on Health, Ch.2 p.21.
Antioxidant IC80=12 uM
*
Antioxidant IC50=54.2 uM
*
Antiperoxidant IC50=36 uM
Planta Medica, 57: A54, 1991.
Antipolio
Jim Duke's personal files.
Antiradicular 10 uM
Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antiradicular 9 x quercetin
*
Antiseptic
*
Antisunburn
*
Antithyroid
Jim Duke's personal files.
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antitumor (Colon)
*
Antitumor (Forestomach)
*
Antitumor (Liver)
*
Antitumor (Skin)
*
Antitumor-Promoter IC25=10 uM
*
Antiulcer
Economic & Medicinal Plant Research, 6: 189.
Antiviral
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Autotoxic
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective
*
Chemopreventive
*
Cholagogue
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Clastogenic
Friedman, M. and Dao, L. 1990. Effect of Autoclaving and Conventional and Microwave Baking on the Ergot Alkaloid and Chlorogenic Acid Contents of Morning Glory (Ipomoea tricolor Cav. cv.) Heavenly Blue Seeds. J. Agric. Food Chem. 38: 805-808.
CNS-Active
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
CNS-Stimulant 1/6 Caffeine
*
Collagen-Sparing
*
Diuretic
*
Fungicide
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Hepatoprotective
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Histamine-Inhibitor
*
Hypoglycemic
*
Immunostimulant
*
Insectifuge
Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Interferonogenic
Economic & Medicinal Plant Research, 1: 124.
Juvabional
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Leukotriene-Inhibitor
*
Lipoxygenase-Inhibitor IC23=5 mM
Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Metal-Chelator
McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
NO-Genic
*
Ornithine-Decarboxylase-Inhibitor
Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Oviposition-Stimulant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
*
Sunscreen
*
Sweetener
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Vulnerary
*
|
||||||
| 0 | DELTA-10(18)-ACETYLANDROMEDOL | Leaf | -- | -- | -- | * |
| 40 | EPICATECHIN | Leaf | -- | -- | -- | * |
|
Allelochemic IC100=1 mM
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Anabolic
*
Antiaggregant IC94=200 ug/ml
*
Antianaphylactic
*
Antibacterial MIC=>1,000 ug/ml
*
Anticomplementary 1/2 aspirin
*
Antidiabetic 30 mg/kg rat
*
AntiEBV
Economic & Medicinal Plant Research, 6: 189.
Antifeedant
*
Antihepatitic
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
AntiHIV EC50=2 ug/ml
*
Antihyperglycemic
*
Antiinflammatory
*
Antileukemic IC50=>10 ug/ml
*
Antilipoperoxidant
*
Antimutagenic
*
Antioxidant 2.5 x Vit. E
*
Antioxidant IC50=10.2 uM
*
Antioxidant IC50=6.3 ug/ml
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antioxidant 3/4 quercetin
*
Antiperoxidant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic
*
Choline-Sparing
Singleton, V.L. 1981. Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods. Advances in Food Research 27: 149-217.
Hepatotropic
*
Hypocholesterolemic
Singleton, V.L. 1981. Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods. Advances in Food Research 27: 149-217.
Hypoglycemic
*
Insulinogenic
Economic & Medicinal Plant Research, 6: 170.
Interleukin-1-alpha-Inhibitor
*
Interleukin-6-mRNA-Inhibitor
*
Lipoxygenase-Inhibitor IC50=140 uM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Lipoxygenase-Inhibitor IC97=5 mM
Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
NO-Inhibitor
*
Pancreatogenic
*
Peroxynitrite-Scavenger IC50=0.181 ug/ml
*
Pesticide
*
Propecic
*
TNF-alpha-Inhibitor
*
Xanthine-Oxidase-Inhibitor IC50=>40
*
|
||||||
| 2 | FRIEDELIN | Plant | -- | -- | -- | * |
|
Antiinflammatory 30 mg/kg
*
Diuretic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
|
||||||
| 7 | GOSSYPETIN | Plant | -- | -- | -- | * |
|
ACE-Inhibitor IC60-90=333 ug/ml
*
Antibacterial
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic
Economic & Medicinal Plant Research, 6: 235.
Antioxidant
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Lipoxygenase-Inhibitor IC50 (uM)=10
*
Pesticide
*
Pigment
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
|
||||||
| 0 | MALVIDIN-3,5-DIGLUCOSIDE | Plant | -- | -- | -- | * |
| 2 | MALVIN | Plant | -- | -- | -- | * |
|
Antioxidant
*
Pigment
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
|
||||||
| 34 | MYRICETIN | Plant | -- | -- | -- | * |
|
Allelochemic IC82=1 mM
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antiallergenic
*
Antibacterial MIC=20-500 ug/ml
*
Antifeedant IC52=<1,000 ppm diet
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antigastric
*
Antigingivitic MIC=20 ug/ml
*
Antigonadotrophic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihistaminic
*
AntiHIV
*
Antiinflammatory
Oriental Materia Medica (three volumes by Dr. Hsu and collaborators)
Antimutagenic ID50=2-5 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant IC50=3.9 ug/ml
*
Antioxidant 1.4 uM
*
Antioxidant IC99=200 ppm
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antiperiodontic MIC=20 ug/ml
*
Antiplaque MIC=20 ug/ml
*
Antiseptic MIC=20 ug/ml
*
Antiviral
*
Apoptotic 60 uM
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide MIC=150 ug/ml
Planta Medica, 57: A43, 1991.
COMP-Inhibitor
Dullo, A. G., et al. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am. J. Clinical Nutrition, 70: 1040-1045.
Diuretic
Oriental Materia Medica (three volumes by Dr. Hsu and collaborators)
Hypoglycemic
Economic & Medicinal Plant Research, 6: 170.
Larvistat IC50=2.6-3.5 mM/kg diet
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Mutagenic
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Oxidase-Inhibitor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
*
Quinone-Reductase-Inducer 36 uM
Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Topoisomerase-I-Inhibitor IC50=11.9 ug/ml
*
Topoisomerase-II-Inhibitor IC50=11.9 ug/ml
*
Tyrosine-Kinase-Inhibitor
Economic & Medicinal Plant Research, 6: 170.
Vasodilator
*
|
||||||
| 0 | RHODODENDRIN | Plant | -- | -- | -- | * |
| # Activity | Chemical Name | Part | Low PPM | High PPM | StdDev | *Reference |
|---|
| # Chemical | Activity Name | *Reference |
|---|---|---|
 |
||
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.