Isatis tinctoria | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Dyer's Woad

How used

Medicinal

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Activities: 319

Chemicals w/Activities: 19

All Chemicals: 30

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Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	1-SULFO-3-INDOLYLMETHYLGLUCOSINOLATE	Plant	--	--	--	*
1	3-BUTENYL-ISOTHIOCYANATE	Root	--	--	--	*
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
2	ARSENIC	Root	--	132.0	5.38	*
Anorexic Forest H. Nielsen, USDA, Grand Forks, various publications. Pesticide *
0	BETA-GALACTAN	Plant	--	--	--	*
28	CALCIUM	Root	--	16300.0	0.97	*
Antiallergic 500 mg/day * Antianxiety Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiarrhythmic 500-1,500 mg * Antiarthritic 1,000 mg/day * Antiatherosclerotic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticlimacteric 1,000-1,500 mg/day * Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Aluminum) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 1,000-1,500 mg/day * Antiobesity * Antiosteoporotic 500-2,000 mg/day * Antiperiodontitic 750 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. AntiPMS 1 g/day * Antirheumatic 1,000 mg/day * Antistress 500-1,500 mg/day * Antitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anxiolytic 500-1,500 mg/day * Calcium-Channel-Blocker * Diuretic * Hypocholesterolemic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Laxative 1,000-1,200 mg * Tranquilizer 500-1,500 mg/day * Vasodilator *
0	CICEROSE	Plant	--	--	--	*
12	COPPER	Root	--	10.0	-0.19	*
Antianemic * Antiarthritic * Antidiabetic 2-4 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antifatigue * Antiinflammatory Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antinociceptive Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Cardioprotective * Contraceptive Martindale's 28th Hypocholesterolemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Immunomodulator * Schizophrenigenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
2	ERUCIC-ACID	Seed	26460.0	80640.0	0.04	*
Antitumor * Lubricant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	FAT	Seed	126000.0	384000.0	0.62	*
0	GAMMA-GALACTAN	Plant	--	--	--	*
1	INDICAN	Root	--	--	--	*
Carcinogenic *
6	IRON	Root	--	150.0	-0.22	*
Antiakathisic Martindale's 29th Antianemic Martindale's 29th Anticanker * Anticheilitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenorrhagic 100 mg/day/wmn/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Prooxidant *
0	ISATAN	Plant	--	--	--	*
75	KAEMPFEROL	Plant	--	--	--	*
11B-HSD-Inhibitor * 5-Lipoxygenase-Inhibitor IC50 (uM)=20 * Aldose-Reductase-Inhibitor 100 uM Oliveira, T. T., Nagem, T. J., Miranda, L. C. G., Paula, V. F., Teixeira, M. A. 1997. Inhibitory Action on Aldose Reductase by Soybean Flavonoids. J Braz Chem Soc, 8(3): 211-213. Antiaflatoxin IC50=8.73 uM * Antiaflatoxin IC50=3.28 ppm * Antiaggregant 30 uM * Antiallergic * Antibacterial 20 ug/ml * Anticancer * Antifertility 250 mg/kg/day/60 days/orl rat Kumar, P., Dixit, V.P., and Khanna, P. Antifertility Studies of Kaempferol: Isolation and Identification from Tissue Culture of some Medicinally Important Plant Species. Plantes medicinales et phytotherapie, 23: 193-201, 1989. Antigingivitic 20 ug/ml Antiherpetic 23-92 ug/ml Amoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992. Antihistaminic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiimplantation * Antiinflammatory 20 mg/kg * Antiinflammatory 200 mg/kg ipr rat * Antileukemic IC50=3.1 ug/ml Life Sciences 55: 1061. Antilymphocytic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antimutagenic ID50=10-40 nM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Antioxidant 3/4 quercetin * Antioxidant IC50=40 uM * Antioxidant IC50=1.2 ug/ml * Antiperiodontic 20 ug/ml * Antiplaque 20 ug/ml * Antiradicular 7 x quercetin * Antiseptic 20 ug/ml * Antiserotonin 200 mg/kg ipr rat * Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antistaphylococcic * Antitumor * Antitumor-Promoter Yasukawa, K., Takido, M., Takeuchi, M., Sato, Y., Nitta, K., and Nakagawa, S. 1989. Inhibitory Effects of Flavonol Glycosides on 12-O-Tetradecanoylphorbol-13-acetate-Induced Tumor Promotion. Chem. Pharm. Bull. 38(3): 774-776, 1990. Antiulcer 50-200 mg/kg ipr rat * Antiviral 23-92 ug/ml * Apoptotic 60 uM * Aromatase-Inhibitor IC12=1 uM/l Journal of Medicinal Food 2: 235.1999. cAMP-Phosphodiesterase-Inhibitor * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carcinogenic Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp. Choleretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Copper-Chelator * COX-2-Inhibitor * Cyclooxygenase-Inhibitor IC50 (uM) =20 * Cytotoxic * Diaphoretic? Lawrence Review of Natural Products, Dec-90. Diuretic * Estrogenic EC50=0.1-25 uM/l Journal of Medicinal Food 2: 227.1999. Estrogenic EC50=0.56 uM * Fungicide 20 ug/ml Father Nature's Farmacy: The aggregate of all these three-letter citations. Hepatoprotective IC50=5.46 uM * Hepatoprotective IC50=1.30 ppm * HIV-RT-Inhibitor IC50=50-150 ug/ml Garcia, J., Morin,* C., Nyasse, B., Sondengam, B-L., Tchouankeu, J-C., and Tsamo, E. Complete Structural Assignments Of An Ergosterol Derivative From Entandrophragma utile. Journal of Natural Products, 54(1): 136-142, 1991. Hypotensive * ICAM-1-Inhibitor * iNOS-Inhibitor IC50=13.9 uM * iNOS-Inhibitor IC50=<15 uM * Inotropic * Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. JNK-Inhibitor * Lipoxygenase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. MAO-Inhibitor * Mutagenic * Natriuretic * Neuroprotective * NO-Inhibitor IC50=13.9 uM * PAF-Inhibitor * Pesticide * Protisticide Meckes, M., Calzada, F., Tapia-Contreras, A., Cedillo-Rivera, R. 1999. Antiprotozoal Properties of Helianthemum glomeratum. Phytotherapy Research, 13(2): 102-105. Quinone-Reductase-Inducer 3 uM * Teratologic * TNF-alpha-Inhibitor IC50=3.99 uM * Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237. Topoisomerase-II-Inhibitor IC50=8.1 ug/ml Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225. Tyrosinase-Inhibitor ID50=230 uM * Uterotrophic EC50=0.1-25 uM/l Journal of Medicinal Food 2: 227.1999. Vasodilator *
27	LINOLEIC-ACID	Seed	23940.0	72960.0	-0.29	*
5-Alpha-Reductase-Inhibitor * Antiacne * Antialopecic * Antianaphylactic Economic & Medicinal Plant Research, 6: 189. Antiandrogenic * Antiarteriosclerotic * Antiarthritic Economic & Medicinal Plant Research, 6: 189. Anticoronary Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antieczemic Economic & Medicinal Plant Research, 6: 189. Antifibrinolytic Economic & Medicinal Plant Research, 1: 53. Antigranular * Antihistaminic Economic & Medicinal Plant Research, 6: 189. Antiinflammatory IC50=31 uM * Antileukotriene-D4 IC50=31 uM * Antimenorrhagic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). AntiMS Economic & Medicinal Plant Research, 6: 189. Antiprostatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carcinogenic Science News, 146: 421. Comedolytic * Hepatoprotective * Hypocholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.) Immunomodulator Economic & Medicinal Plant Research, 6: 189. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Metastatic Science News, 146: 421. Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Propecic *
0	LINOLENIC-ACID	Seed Oil	30240.0	92160.0	-0.67	*
0	LUPEOSE	Plant	--	--	--	*
65	MAGNESIUM	Root	--	4410.0	0.98	*
Antiaggregant 400 mg/day * Antialcoholic * Antianginal 400 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antianorectic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antianxiety 400 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiarrhythmic 400 mg/day * Antiarthritic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiasthmatic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiatherosclerotic 400 mg/day * Anticephalagic * AntiCFS * Anticlimacteric 500-750 mg/day * Anticonvulsant Facciola, S. 1998. Cornucopia - A Source Book of Edible Plants. Kampong Publications, Vista CA. 713 pp. Anticoronary 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidiabetic 400-800 mg/man/day * Antidysmenorrheic 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiendometriotic 500 mg/day * Antienterotic * Antiepileptic 450 mg/day * Antifatigue * Antifibromyalgic 200-300 mg 3x/day * Antigastrotic * Antiglaucomic * Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antihypoglycemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiinflammatory 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antilithic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). AntiLyme 400-1,000 mg * Antimastalgic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antimenopausal 500-750 mg/day * Antimigraine 200 mg/day/man Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antimitral-valve-prolapse * AntiMS * Antinephrolytic * Antineurotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiosteoporotic 500-1,000 mg/day/wmn/orl * Antiplaque 500-1,000 mg/day * AntiPMS 400-800 mg/day/wmn orl * AntiPMS 400-800 mg/day/wmn/orl * AntiRaynaud's 280-350 mg/day * Antiretinopathic 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antispasmodic * Antispasmophilic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antistress 500-750 mg/day * Antistroke 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antisyndrome-X 400 mg/man/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Anxiolytic 500-750 mg/day * Calcium-Antagonist * Cardioprotective * CNS-Depressant Facciola, S. 1998. Cornucopia - A Source Book of Edible Plants. Kampong Publications, Vista CA. 713 pp. Diuretic * Hypocholesterolemic 400 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 260-500 mg/day * Immunomodulator * Insulinogenic 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Laxative 300-500 mg/day * Litholytic * Myorelaxant 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Neurotransmitter * Tranquilizer 500-750 mg/day * Uterorelaxant 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Vasodilator *
14	MANGANESE	Root	--	181.0	1.62	*
Antialcoholic Forest H. Nielsen, USDA, Grand Forks, various publications. Antianemic Martindale's 28th Antiarthritic * Antidiabetic 10-30 mg/man/day * Antidiabetic 3-5 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antidiscotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidyskinetic Martindale's 28th Antiepileptic 450 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Antiototic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antioxidant * AntiPMS * Antisyndrome-X 10-30 mg/man/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypoglycemic 10-30 mg/man/day *
0	MANNEOTETROSE	Plant	--	--	--	*

List of all activity chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Isatis tinctoria (Brassicaceae)

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