An official website of the United States government.
Plant Guazuma tomentosa (Sterculiaceae)
Download a full report in PDF format
How used
Medicinal
Data Views
| # Activity | Chemical Name | Part | Low PPM | High PPM | StdDev | *Reference |
|---|---|---|---|---|---|---|
| 1 | 3-O-ACETYLOLEANOLIC-ACID | Stem | -- | -- | -- | * |
|
Antiinflammatory
*
|
||||||
| 47 | BETA-SITOSTEROL | Bark | -- | 270.0 | 0.64 | * |
|
Androgenic
*
Angiogenic
*
Anorexic
Martindale's 28th
Antiadenomic
Merck 11th Edition
Antiandrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
*
Anticancer (Lung)
*
Antiedemic IC54=320 mg/kg orl
*
Antiestrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
*
Antileukemic
*
Antilymphomic
*
Antimutagenic 250 ug/ml
*
Antiophidic 2.3 mg mus
Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
*
Antiprogestational
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
*
Antiprostatadenomic
Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
*
Antipyretic
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
*
Antitumor (Lung)
*
Antiviral
Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
*
Artemicide LC50=110 ppm
Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
*
Estrogenic
*
Febrifuge
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
*
Hypocholesterolemic 2-6 g/man/day/orl
Martindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orl
Martindale's 28th
Hypoglycemic
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
*
Pesticide
*
Spermicide
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
*
|
||||||
| 47 | BETA-SITOSTEROL | Leaf | -- | -- | -- | * |
|
Androgenic
*
Angiogenic
*
Anorexic
Martindale's 28th
Antiadenomic
Merck 11th Edition
Antiandrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
*
Anticancer (Lung)
*
Antiedemic IC54=320 mg/kg orl
*
Antiestrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
*
Antileukemic
*
Antilymphomic
*
Antimutagenic 250 ug/ml
*
Antiophidic 2.3 mg mus
Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
*
Antiprogestational
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
*
Antiprostatadenomic
Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
*
Antipyretic
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
*
Antitumor (Lung)
*
Antiviral
Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
*
Artemicide LC50=110 ppm
Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
*
Estrogenic
*
Febrifuge
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
*
Hypocholesterolemic 2-6 g/man/day/orl
Martindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orl
Martindale's 28th
Hypoglycemic
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
*
Pesticide
*
Spermicide
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
*
|
||||||
| 47 | BETA-SITOSTEROL | Stem | -- | -- | -- | * |
|
Androgenic
*
Angiogenic
*
Anorexic
Martindale's 28th
Antiadenomic
Merck 11th Edition
Antiandrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
*
Anticancer (Lung)
*
Antiedemic IC54=320 mg/kg orl
*
Antiestrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
*
Antileukemic
*
Antilymphomic
*
Antimutagenic 250 ug/ml
*
Antiophidic 2.3 mg mus
Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
*
Antiprogestational
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
*
Antiprostatadenomic
Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
*
Antipyretic
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
*
Antitumor (Lung)
*
Antiviral
Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
*
Artemicide LC50=110 ppm
Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
*
Estrogenic
*
Febrifuge
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
*
Hypocholesterolemic 2-6 g/man/day/orl
Martindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orl
Martindale's 28th
Hypoglycemic
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
*
Pesticide
*
Spermicide
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
*
|
||||||
| 13 | BETULIN | Bark | -- | 17.0 | -0.41 | * |
|
Anticarcinomic
*
Antifeedant
*
Antiflu
*
AntiHIV 6.1 uM
*
Antiinflammatory
Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral 6.1 uM
*
Aphidifuge
Lugemwa, F.N., Huang, F-Y., Bentley, M.D., Mendel, M.J., and Alford, A.R. 1990. A Heliothis zea Antifeedant from the Abundant Birchbark Triterpene Betulin. J. Agric. Food Chem. 38(2): 493-494.
Cytotoxic 600 ppm
*
Cytotoxic 8.6 uM
*
Hypolipemic
*
Prostaglandin-Synthesis-Inhibitor IC50=119 uM
Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
Topoisomerase-II-Inhibitor IC50=38.6 uM
*
|
||||||
| 13 | BETULIN | Tb | -- | 17.0 | -- | Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705. |
|
Anticarcinomic
*
Antifeedant
*
Antiflu
*
AntiHIV 6.1 uM
*
Antiinflammatory
Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral 6.1 uM
*
Aphidifuge
Lugemwa, F.N., Huang, F-Y., Bentley, M.D., Mendel, M.J., and Alford, A.R. 1990. A Heliothis zea Antifeedant from the Abundant Birchbark Triterpene Betulin. J. Agric. Food Chem. 38(2): 493-494.
Cytotoxic 600 ppm
*
Cytotoxic 8.6 uM
*
Hypolipemic
*
Prostaglandin-Synthesis-Inhibitor IC50=119 uM
Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
Topoisomerase-II-Inhibitor IC50=38.6 uM
*
|
||||||
| 2 | FRIEDELIN | Stem | -- | -- | -- | * |
|
Antiinflammatory 30 mg/kg
*
Diuretic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
|
||||||
| 2 | FRIEDELIN | Bark | -- | 430.0 | -1.00 | * |
|
Antiinflammatory 30 mg/kg
*
Diuretic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
|
||||||
| 0 | FRIEDELIN-3ALPHA-ACETATE | Leaf | -- | -- | -- | * |
| 0 | FRIEDELIN-3BETA-OL | Leaf | -- | -- | -- | * |
| 1 | KAEMPFERITRIN | Flower | -- | -- | -- | * |
|
Antiinflammatory
*
|
||||||
| 75 | KAEMPFEROL | Flower | -- | -- | -- | * |
|
11B-HSD-Inhibitor
*
5-Lipoxygenase-Inhibitor IC50 (uM)=20
*
Aldose-Reductase-Inhibitor 100 uM
Oliveira, T. T., Nagem, T. J., Miranda, L. C. G., Paula, V. F., Teixeira, M. A. 1997. Inhibitory Action on Aldose Reductase by Soybean Flavonoids. J Braz Chem Soc, 8(3): 211-213.
Antiaflatoxin IC50=8.73 uM
*
Antiaflatoxin IC50=3.28 ppm
*
Antiaggregant 30 uM
*
Antiallergic
*
Antibacterial 20 ug/ml
*
Anticancer
*
Antifertility 250 mg/kg/day/60 days/orl rat
Kumar, P., Dixit*, V.P., and Khanna, P. Antifertility Studies of Kaempferol: Isolation and Identification from Tissue Culture of some Medicinally Important Plant Species. Plantes medicinales et phytotherapie, 23: 193-201, 1989.
Antigingivitic 20 ug/ml
*
Antiherpetic 23-92 ug/ml
Amoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Antihistaminic
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiimplantation
*
Antiinflammatory 20 mg/kg
*
Antiinflammatory 200 mg/kg ipr rat
*
Antileukemic IC50=3.1 ug/ml
Life Sciences 55: 1061.
Antilymphocytic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic ID50=10-40 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant IC50=40 uM
*
Antioxidant 3/4 quercetin
*
Antioxidant IC50=1.2 ug/ml
*
Antiperiodontic 20 ug/ml
*
Antiplaque 20 ug/ml
*
Antiradicular 7 x quercetin
*
Antiseptic 20 ug/ml
*
Antiserotonin 200 mg/kg ipr rat
*
Antispasmodic
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antistaphylococcic
*
Antitumor
*
Antitumor-Promoter
Yasukawa, K., Takido, M., Takeuchi, M., Sato, Y., Nitta, K., and Nakagawa, S. 1989. Inhibitory Effects of Flavonol Glycosides on 12-O-Tetradecanoylphorbol-13-acetate-Induced Tumor Promotion. Chem. Pharm. Bull. 38(3): 774-776, 1990.
Antiulcer 50-200 mg/kg ipr rat
*
Antiviral 23-92 ug/ml
*
Apoptotic 60 uM
*
Aromatase-Inhibitor IC12=1 uM/l
Journal of Medicinal Food 2: 235.1999.
cAMP-Phosphodiesterase-Inhibitor
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic
Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu
Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp.
Choleretic
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Copper-Chelator
*
COX-2-Inhibitor
*
Cyclooxygenase-Inhibitor IC50 (uM) =20
*
Cytotoxic
*
Diaphoretic?
Lawrence Review of Natural Products, Dec-90.
Diuretic
*
Estrogenic EC50=0.56 uM
*
Estrogenic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Fungicide 20 ug/ml
Father Nature's Farmacy: The aggregate of all these three-letter citations.
Hepatoprotective IC50=5.46 uM
*
Hepatoprotective IC50=1.30 ppm
*
HIV-RT-Inhibitor IC50=50-150 ug/ml
Garcia, J., Morin,* C., Nyasse, B., Sondengam, B-L., Tchouankeu, J-C., and Tsamo, E. Complete Structural Assignments Of An Ergosterol Derivative From Entandrophragma utile. Journal of Natural Products, 54(1): 136-142, 1991.
Hypotensive
*
ICAM-1-Inhibitor
*
iNOS-Inhibitor IC50=<15 uM
*
iNOS-Inhibitor IC50=13.9 uM
*
Inotropic
*
Iodothyronine-Deiodinase-Inhibitor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
JNK-Inhibitor
*
Lipoxygenase-Inhibitor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
MAO-Inhibitor
*
Mutagenic
*
Natriuretic
*
Neuroprotective
*
NO-Inhibitor IC50=13.9 uM
*
PAF-Inhibitor
*
Pesticide
*
Protisticide
Meckes, M., Calzada, F., Tapia-Contreras, A., Cedillo-Rivera, R. 1999. Antiprotozoal Properties of Helianthemum glomeratum. Phytotherapy Research, 13(2): 102-105.
Quinone-Reductase-Inducer 3 uM
*
Teratologic
*
TNF-alpha-Inhibitor IC50=3.99 uM
*
Topoisomerase-I-Inhibitor
Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor IC50=8.1 ug/ml
Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225.
Tyrosinase-Inhibitor ID50=230 uM
*
Uterotrophic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Vasodilator
*
|
||||||
| 1 | LIGNOCERIC-ACID | Stem | -- | -- | -- | * |
|
Antihepatotoxic
*
|
||||||
| 176 | QUERCETIN | Flower | -- | -- | -- | * |
|
11B-HSD-Inhibitor
*
5-Lipoxygenase-Inhibitor IC50 (uM)=4
*
Aldehyde-Oxidase-Inhibitor IC70-96=10 uM
*
Aldose-Reductase-Inhibitor 100 uM
*
Aldose-Reductase-Inhibitor 4 ug/ml
Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Aldose-Reductase-Inhibitor IC50=0.84 ug/ml cow
Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Aldose-Reductase-Inhibitor IC50=0.344 uM
Mao, X. M., Zhang, J. Q. 1993. Inhibition of Aldose Reductase by Extracts of Chinese Herbal Medicine. Zhongguo Zhongyao Zazhi , 18(10): 623-624.
Allelochemic IC82=1 mM
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Allergenic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Analgesic
*
Antiaflatoxin IC50=25 uM
*
Antiaflatoxin IC50=7.5 ppm
*
Antiaggregant 30 uM
*
Antiaggregant IC50=55 uM
Economic & Medicinal Plant Research, 5: 333.
Antiaging
*
Antiallergic IC50=14 uM
Jim Duke's personal files.
Antialzheimeran
*
Antianaphylactic
Meli, R., Autore, G., Di Carlo, G., Capasso, F. Inhibitory Action of Quercetin on Intestinal Transit in Mice. Phytotherapy Research 4(5): 201, 1990.
Antiangiogenic
*
Antiarthritic
*
Antiasthmatic IC50=14 uM
*
Antiatherosclerotic
*
Antibacterial
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic (Breast) IC50=1.5 uM
Medline (post 1990 searches filed in my computer)
Anticariogenic ID50=120 ug/ml
*
Anticataract
*
Anticolitic 400 mg/man/3x/day
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticomplementary
*
AntiCrohn's 400 mg/man/3x/day
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticystitic 1,000 mg/day/4 weeks
*
Antidepressant
*
Antidermatitic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antidiabetic
*
Antielastase IC50=0.8 ug/ml
*
Antiencephalitic
Economic & Medicinal Plant Research, 5: 199.
Antiescherichic
*
Antiestrogenic
*
Antifeedant IC52=<1,000 ppm diet
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antifibrosarcomic
*
Antiflu
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antigastric
Rastitel'nye Resursy, 21: 85.
Antigonadotropic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
AntiGTF ID50=120 ug/ml
*
Antihepatotoxic
Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
Antiherpetic 48-150 ug/ml
*
Antihistaminic IC50=<10 uM
*
AntiHIV
*
Antihydrophobic
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antihypertensive
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20-150 mg/kg
Fitoterapia No.5-1990.
Antileishmanic IC50=64
*
Antileukemic 5.5-60 uM
*
Antileukemic IC50=10 uM
Economic & Medicinal Plant Research, 5: 225.
Antileukemic IC50=>10 ug/ml
Life Sciences 55: 1061.
Antileukotriene
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antilipoperoxidant IC67=50
*
Antimalarial IC50=1-6.4 ug/ml
Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antimelanomic
*
Antimetastatic
*
Antimutagenic ID50=2-5 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.62 ug/ml
*
Antimyocarditic
Economic & Medicinal Plant Research, 5: 199.
Antinitrosaminic
*
Antinociceptive
*
Antioxidant IC47=10 uM
*
Antioxidant 4.7 x Vit. E
*
Antioxidant ED50=2.3 uM
Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antioxidant IC96=300 ppm
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antipancreatitic
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiperiodontal
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiperistaltic
*
Antipermeability
*
Antiperoxidant
Planta Medica, 57: A110, 1991.
Antipharyngitic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplaque
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplasmodial IC50=13-64
*
AntiPMS 500 mg/2x/day/wmn
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antipodriac
*
Antipolio
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiproliferant 10 nM
*
Antiprostanoid
*
Antiprostatitic
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antipsoriac
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiradicular IC50=4.6 uM
Planta Medica, 56(6): 695, 1990.
Antispasmodic
*
Antistreptococcic ID50=120 ug/ml
*
Antithiamin
Phenolic Compounds in Food and Their Effects on Health, 69.
Antithrombic
*
Antitrypanosomic IC50=13
*
Antitumor 10 uM
*
Antitumor (Bladder)
*
Antitumor (Breast)
*
Antitumor (Colon)
*
Antitumor (Lung)
*
Antitumor (Ovary)
*
Antitumor (Skin) 20 uM
*
Antitumor-Promoter
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiulcer
*
Antiviral IC50=10 uM
Economic & Medicinal Plant Research, 5: 225.
Antiviral 48-150 ug/ml
Amoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Apoptotic 20-60 uM
*
ATPase-Inhibitor
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Bacteristat 10 mg/ml
*
Bradycardiac
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Calmodulin-Antagonist
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
cAMP-Phosphodiesterase-Inhibitor
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
*
Capillariprotective
Merck 11th Edition
Carcinogenic 40,000 ppm (diet) mus
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Catabolic
*
COMT-Inhibitor
*
Copper-Chelator
*
COX-2-Inhibitor <40 uM
*
Cyclooxygenase-Inhibitor
*
Cytochrome-P450-1A2-Inhibitor
*
Cytotoxic ED50=70 ug/ml
Matsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
Cytotoxic IC82=100 ug/ml
Planta Medica, 57: A113, 1991.
Deiodinase-Inhibitor
Jim Duke's personal files.
Diaphoretic?
Lawrence Review of Natural Products, Dec-90.
Differentiator 5.5 uM
*
Estrogenic 10% genistein
*
Fungicide
*
Glucosyl-Transferase-Inhibitor ID50=120 ug/ml
*
Hemostat
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hepatomagenic 5,000 ppm (diet) rat
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective
*
HIV-RT-Inhibitor IC50=<1 ug/ml
Nakane, H., Fukushima, M., and Ono*, K. Differential Inhibition Of Reverse Transcriptase And Various DNA Polymerases By Digallic Acid And Its Derivatives. Journal of Natural Products, 53(5): 1234-1240, 1990.
Hypoglycemic 100 mg/kg orl rat
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
iNOS-Inhibitor IC50=20 uM
*
Inotropic
*
Insulinogenic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Juvabional
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Larvistat 8,000 ppm diet
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC11=1.25 mM
Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=0.1-5 uM
*
MAO-A-Inhibitor
*
Mast-Cell-Stabilizer
*
Metal-Chelator (Copper)
Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Metalloproteinase-Inhibitor IC50=>42 uM
*
MMP-9-Inhibitor 20 uM
*
Mutagenic
*
NADH-Oxidase-Inhibitor
*
NEP-Inhibitor IC50=>42 uM
*
Neuroprotective 5-25 uM
*
NF-kB-Inhibitor
*
NO-Inhibitor IC50=20 uM
*
NO-Inhibitor IC>50=125 uM
*
NO-Synthase-Inhibitor 5-50 uM
*
Ornithine-Decarboxylase-Inhibitor <10 uM
*
P450-Inducer 5 uM
Father Nature's Farmacy: The aggregate of all these three-letter citations.
P450-Inhibitor 50-100 uM
Father Nature's Farmacy: The aggregate of all these three-letter citations.
Pesticide
*
PGE2-Inhibitor
*
Phospholipase-Inhibitor
*
Plasmodicide
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Proliferant
*
Prostaglandin-Synthesis-Inhibitor 40 ug/ml
Ibewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284.
Protein-Kinase-C-Inhibitor
Naim, M., Zehavi, U., Nagy, S., and Rouseff, R.L. Hydroxycinnamic Acids as Off-Flavor Precursors in Citrus Fruits and Their Products. Phenolic Compounds in Food and Their Effects on Health, Ch.14.
PTK-Inhibitor 0.4-24 uM
*
Quinone-Reductase-Inducer 6 uM
Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Quinone-Reductase-Inducer 13 uM
*
Teratologic
*
TNF-alpha-Inhibitor IC50=3.11 uM
*
Topoisomerase-I-Inhibitor IC50=12.8 ug/ml
*
Topoisomerase-I-Inhibitor IC50=42 uM
*
Topoisomerase-II-Inhibitor IC50=1-6.9 ug/ml
*
Topoisomerase-II-Inhibitor IC50=23-40 uM
*
Tumorigenic 0.1% diet orl rat/yr
Jim Duke's personal files.
Tyrosinase-Inhibitor ID50=70 uM
*
Tyrosine-Kinase-Inhibitor
Economic & Medicinal Plant Research, 6: 170.
Vasodilator
*
VEGF-Inhibitor
*
Xanthine-Oxidase-Inhibitor IC50=10.6 ug/ml
*
Xanthine-Oxidase-Inhibitor 3.1 uM
*
Xanthine-Oxidase-Inhibitor IC50=>0.4 ug/ml
Chem. & Pharm. Bull. 38: 1772.
|
||||||
| 2 | TARAXEROL | Leaf | -- | -- | -- | * |
|
Antisecretory
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiulcer
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
|
||||||
| # Activity | Chemical Name | Part | Low PPM | High PPM | StdDev | *Reference |
|---|
| # Chemical | Activity Name | *Reference |
|---|---|---|
 |
||
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.