Dipteryx odorata | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Dutch Tonka Bean, Tonka Bean

How used

Medicinal

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Activities: 187

Chemicals w/Activities: 16

All Chemicals: 45

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	3',7-DIHYDROXY-4',6-DIMETHOXY-ISOFLAVONE	Plant	--	--	--	Jim Duke's personal files.
0	3',7-DIHYDROXY-4',8-DIMETHOXY-ISOFLAVONE	Plant	--	--	--	Jim Duke's personal files.
0	3'-HYDROXY-8-O-METHYLRETUSIN	Wood	--	--	--	*
0	3'-HYDROXYRETUSIN-8-METHYL-ETHER	Wood	--	--	--	CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
0	3-BETA-ACETOXY-VOUACAPENOL	Seed	--	--	--	Jim Duke's personal files.
0	5,6,7-TRIMETHOXY-3',4-METHYLENEDIOXY-ISOFLAVONE	Bark	--	--	--	Jim Duke's personal files.
0	7,8-DIHYDROXY-4'-METHOXY-ISOFLAVONE	Heart Wood	--	--	--	Jim Duke's personal files.
0	7,8-DIHYDROXY-6,4-DIMETHOXY-ISOFLAVONE	Heart Wood	--	--	--	Jim Duke's personal files.
0	7-HYDROXY-4',8-DIMETHOXY-ISOFLAVONE	Heart Wood	--	--	--	Jim Duke's personal files.
0	7-HYDROXY-5,16-DIEMTHOXY-3',4'-METHYLENE-DIOXY-ISOFLAVONE	Heart Wood	--	--	--	Jim Duke's personal files.
0	8-O-METHYLRETUSIN	Wood	--	--	--	*
13	BETULIN	Bark	--	--	--	CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
Anticarcinomic * Antifeedant * Antiflu * AntiHIV 6.1 uM * Antiinflammatory Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas. Planta Medica, 61: 9. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiviral 6.1 uM Aphidifuge Lugemwa, F.N., Huang, F-Y., Bentley, M.D., Mendel, M.J., and Alford, A.R. 1990. A Heliothis zea Antifeedant from the Abundant Birchbark Triterpene Betulin. J. Agric. Food Chem. 38(2): 493-494. Cytotoxic 600 ppm * Cytotoxic 8.6 uM * Hypolipemic * Prostaglandin-Synthesis-Inhibitor IC50=119 uM Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626. Topoisomerase-II-Inhibitor IC50=38.6 uM *
0	COUMARIC-ACID-BETA-GLUCOSIDE	Seed	--	--	--	CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
57	COUMARIN	Seed	10000.0	35000.0	1.00	CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
Aldose-Reductase-Inhibitor 10 ug/ml cow (weak activity, 11% inhibition) Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 Allelochemic IC100=2 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Analgesic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Anesthetic * Antiaggregant * Antiandrogenic Planta Medica, 56(6): 671, 1990. Antibrucellosic Gawron, A., Gorski, G., Glowniak, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990. Anticancer (Kidney) 400-7,000 mg/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Anticancer (Prostate) 400-7,000 mg/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antidiuretic Antiedemic Shimizu,M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990. Antiesherichic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory Shimizu,M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990. Antilymphedemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimelanomic 50 mg/day * Antimetastatic 50 mg/man/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimitotic Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7. Antimononuccleotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antimycoplasmotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antipsittacotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antipsoriac Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7. Antitoxoplasmotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antitumor 50 mg/day * Antitumor (GI) * Antitumor (Kidney) 400-7,000 mg/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antitumor (Prostate) 400-7,000 mg/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Bacteristat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Bruchiphobe * Cancer-Preventive 5-25 ug/ml Gawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526. Carcinogenic 200 mg/kg orl mus Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Cardiodepressant * Cardiotonic * Chemopreventive * DME-Inhibitor IC50=57.5 uM Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134. Emetic * Estrogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hemorrhagic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hepatotoxic 0.8-1.71 mM/kg orl rat * Hepatotoxic 2,500 ppm diet * Hepatotoxic 100 mg/kg dog * Hypnotic Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990. Hypoglycemic 250-1,000 mg/kg orl Economic & Medicinal Plant Research, 6: 165 Immunostimulant * Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Larvistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Lymphocytogenic 100 mg/day Gawron, A., Gorski, G., Glowniak, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990. Lymphokinetic Narcotic * Ovicide * Pesticide * Phagocytotic Planta Medica, 56(6): 671, 1990. Piscicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Respirodepressant * Rodenticide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Sedative Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990.
0	DIPTERYXIN	Wood	--	--	--	*
0	DIPTERYXINE	Bark	--	--	--	*
0	FAT	Seed	--	250000.0	-0.08	CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
61	FERULIC-ACID	Leaf	--	--	--	Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
Allelopathic Holappa, L.D., and Blum, U. 1991. Effects of Exogenously Applied Ferulic Acid, a Potential Allelopathic Compound, on Leaf Growth, Water Utilization, and Endogenous Abscisic Acid Levels of Tomato, Cucumber, and Bean. J. of Chemical Ecology, 17(5): 865. Analgesic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 69. Antiaggregant Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990. Antiallergic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antiarrhythmic Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticancer (Colon) * Anticancer (Forestomach) * Anticancer (Liver) * Anticancer (Skin) * Anticarcinogenic * Antidysmenorrheic * Antiestrogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiherpetic * Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. Antileukemic IC50=25-56 ug/ml Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18. Antineoplastic (Stomach) * Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18. Antioxidant 1/2 BHA * Antioxidant EC50=9-15 ug/ml * Antioxidant 1/3 quercetin * Antioxidant 3,000 uM * Antioxidant IC51=200 ppm * Antiradicular EC50=9-15 ug/ml * Antiradicular IC50=116-124 uM * Antiserotonin Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antithrombic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antitumor (Colon) * Antitumor (Forestomach) * Antitumor (Liver) * Antitumor (Skin) * Antitumor-Promoter IC46=10 uM Cancer Research, 48: 5941. Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Arteriodilator Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cardiac Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990. Cholagogue Pharmazie, 46: 156, 1991. Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Hepatoprotective Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Hepatotropic * Herbicide Angewandte Botanik 68(5/6)=1994. Page 195. Hydrocholerectic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hypolipidemic * Immunostimulant Economic & Medicinal Plant Research, 1: 124. Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994. Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25. Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. Pesticide * Phagocytotic * Preservative Merck 11th Edition Prostaglandigenic * Prostaglandin-Synthesis-Inhibitor 0.58-3.2 mM Xu, L. N., Yu, W. G., Tian, J. Y., Liu, Q. Y. 1990. Effect of Sodium Ferulate on Arachidonic Acid Metabolism. Yao Hsueh Hsueh Pao, 25(6): 412-416. Sunscreen Chemical Marketing Reporter; a weekly tabloid, 9/10/92. Uterosedative 30-100 mg/kg ivn rat Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
8	GENTISIC-ACID	Leaf	--	--	--	Jim Duke's personal files.
Analgesic Merck 11th Edition Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antifeedant * Antiinflammatory Merck 11th Edition Antioxidant 1/3 BHA * Antirheumatic Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp. Antiviral Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
27	LINOLEIC-ACID	Seed	--	3850.0	-0.88	*
5-Alpha-Reductase-Inhibitor * Antiacne * Antialopecic * Antianaphylactic Economic & Medicinal Plant Research, 6: 189. Antiandrogenic * Antiarteriosclerotic * Antiarthritic Economic & Medicinal Plant Research, 6: 189. Anticoronary Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antieczemic Economic & Medicinal Plant Research, 6: 189. Antifibrinolytic Economic & Medicinal Plant Research, 1: 53. Antigranular * Antihistaminic Economic & Medicinal Plant Research, 6: 189. Antiinflammatory IC50=31 uM * Antileukotriene-D4 IC50=31 uM * Antimenorrhagic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). AntiMS Economic & Medicinal Plant Research, 6: 189. Antiprostatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carcinogenic Science News, 146: 421. Comedolytic * Hepatoprotective * Hypocholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.) Immunomodulator Economic & Medicinal Plant Research, 6: 189. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Metastatic Science News, 146: 421. Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Propecic *

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Dipteryx odorata (Fabaceae)

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