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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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  1. Home
  2. URSOLIC-ACID

URSOLIC-ACID

Chemical ID
URSOLICACID
Ubiquitous
No

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Cardiotonic *
Choleretic 5-20 mg/kg orl Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
CNS-Depressant *
COX-2-Inhibitor IC50=130 uM/ *
Cyclooxygenase-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cytotoxic 7.2 uM *
Cytotoxic 50 ppm *
Cytotoxic ED50=3.75 ug/ml *
Diuretic *
Elastase-Inhibitor IC50=~15 uM *
Hepatoprotective 10 mg/kg *
Hepatoprotective 1-100 ug/ml *
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypotensive *
Immunomodulator *
Leucocytogenic *
Lipoxygenase-Inhibitor IC50=0.18 mM *
MMP-9-Inhibitor IC80=10 uM *
Ornithine-Decarboxylase-Inhibitor *
Pesticide *
Download these results as:
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Sanguisorba officinalis Plant *
Satureja hortensis Leaf 1700.0 -0.4 ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Satureja hortensis Stem 1000.0 1.2 ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Satureja montana Leaf 16000.0 -0.1 *
Satureja montana Plant 16000.0 0.0 ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Sorbus aucubaria Fruit *
Syringa vulgaris Leaf List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Syzygium claviflorum Leaf 20.0 -0.4 Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Teucrium chamaedrys Plant Abstract (See species file)
Teucrium polium Plant Rizk, A.F.M., The Phytochemistry of the Flora of Qatar, Scientific and Applied Research Centre, University of Qatar, Kingprint, Richmond, UK, 1986.
Teucrium scordium Plant ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Teucrium scorodonia Leaf 3000.0 -0.3 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Thevetia peruviana Leaf 1500.0 -0.4 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Thymus serpyllum Plant 7500.0 9100.0 -0.4 *
Thymus vulgaris Plant 15000.0 18800.0 0.1 *
Uncaria tomentosa Plant *
Urtica dioica Root 15.0 -1.0 Jim Duke's personal files.
Vaccinium corymbosum Plant *
Vaccinium macrocarpon Fruit *
Vaccinium myrtillus Fruit 2500.0 -0.3 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.