Chemical URSOLIC-ACID | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

URSOLICACID

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Cardiotonic	not available	Duke, 1992 *
Choleretic	5-20 mg/kg orl	Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
CNS-Depressant	not available	Duke, 1992 *
COX-2-Inhibitor	IC50=130 uM/	Duke, 1992 *
Cyclooxygenase-Inhibitor	not available	Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cytotoxic	7.2 uM	Duke, 1992 *
Cytotoxic	50 ppm	Duke, 1992 *
Cytotoxic	ED50=3.75 ug/ml	Duke, 1992 *
Diuretic	not available	Duke, 1992 *
Elastase-Inhibitor	IC50=~15 uM	Duke, 1992 *
Hepatoprotective	10 mg/kg	Duke, 1992 *
Hepatoprotective	1-100 ug/ml	Duke, 1992 *
Hypoglycemic	not available	Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypotensive	not available	Duke, 1992 *
Immunomodulator	not available	Duke, 1992 *
Leucocytogenic	not available	Duke, 1992 *
Lipoxygenase-Inhibitor	IC50=0.18 mM	Duke, 1992 *
MMP-9-Inhibitor	IC80=10 uM	Duke, 1992 *
Ornithine-Decarboxylase-Inhibitor	not available	Duke, 1992 *
Pesticide	not available	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Malus domestica	Pericarp	not available	not available	not available	Duke, 1992 *
Marrubium vulgare	Flower	not available	not available	not available	Duke, 1992 *
Marrubium vulgare	Leaf	not available	1000.0	-0.4	Duke, 1992 *
Marrubium vulgare	Plant	not available	1200.0	-0.7	Duke, 1992 *
Melaleuca leucadendra	Plant	not available	not available	not available	Duke, 1992 *
Melissa officinalis	Plant	not available	not available	not available	Duke, 1992 *
Mentha spicata	Shoot	not available	not available	not available	Duke, 1992 *
Mentha spicata	Leaf	not available	not available	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Mentha spicata	Plant	not available	not available	not available	Duke, 1992 *
Mentha x rotundifolia	Tissue Culture	not available	not available	not available	Jim Duke's personal files.
Monarda didyma	Leaf	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Morinda citrifolia	Leaf	not available	not available	not available	Duke, 1992 *
Nepeta cataria	Plant	not available	not available	not available	Duke, 1992 *
Nepeta cataria	Shoot	not available	10300.0	1.8	Duke, 1992 *
Nerium oleander	Plant	not available	43000.0	1.3	Duke, 1992 *
Ocimum basilicum	Stem	not available	845.0	0.8	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Ocimum basilicum	Flower	not available	1740.0	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Ocimum basilicum	Leaf	not available	not available	not available	Duke, 1992 *
Ocimum basilicum	Sprout Seedling	not available	63.0	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Ocimum canum	Shoot	not available	not available	not available	=ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp