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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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  1. Home
  2. THEOPHYLLINE

THEOPHYLLINE

Chemical ID
THEOPHYLLINE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=600 (orl mus) CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
LDlo=100 (orl cat) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LDlo=350 (orl rbt) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LDlo=115 (ivn rbt) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LD50=200 (scu mus) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
ADI=60-200 orl/man/day Martindale's 28th

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Choleretic *
CNS-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Diuretic 15 mg/kg ivn rbt Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Fetotoxic 100 mg/kg *
Herbicide IC58=100 ppm Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Hypertensive LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The
Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
Hyperuricemic Martindale's 29th
Hypoglycemic *
Myocardiotonic Martindale's 29th
Myorelaxant 100 uM *
Pesticide *
Prostaglandin-Secretor 10 mg/kg orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Stimulant *
Tachycardic Martindale's 29th
Teratogenic CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
Vasodilator *
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Camellia sinensis Seed *
Camellia sinensis Leaf 2.0 4.0 -1.0 *
Coffea arabica Leaf *
Coffea arabica Seed 5.0 -0.8 *
Ilex paraguariensis Leaf 0.0 500.0 1.0 *
Paullinia cupana Seed 0.0 2500.0 0.5 *
Theobroma angustifolium Petiole 47.0 52.0 -1.3 *
Theobroma angustifolium Seed 84.0 96.0 -0.8 *
Theobroma angustifolium Testa 113.0 116.0 -1.3 *
Theobroma bicolor Fruit 453.0 522.0 *
Theobroma bicolor Petiole 53.0 273.0 1.1 *
Theobroma bicolor Seed 196.0 216.0 -0.7 *
Theobroma bicolor Testa 210.0 211.0 0.3 *
Theobroma cacao Petiole 58.0 188.0 0.2 *
Theobroma cacao Plant *
Theobroma cacao Seed 0.0 4739.0 1.7 *
Theobroma cacao Testa 130.0 257.0 1.1 *