Chemical GENISTEIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

GENISTEIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Calcium-Antagonist	50 uM gpg	Duke, 1992 *
Cancer-Preventive	not available	Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective	not available	Journal of Medicinal Food 2: 163.1999.
Catechol-O-Methyltransferase-Inhibitor	not available	Duke, 1992 *
Cytotoxic	>50 ug/ml (185 uM)	Medline (post 1990 searches filed in my computer)
Cytotoxic	IC89=10 ug/ml	Planta Medica, 57: A113, 1991.
DOPA-Decarboxylase-Inhibitor	not available	Duke, 1992 *
Estrogen-Agonist	0.1-1 uM/l	Journal of Medicinal Food 2: 139.1999.
Estrogenic	EC50=0.1-25 uM/l	Duke, 1992 *
Flatulent	not available	Duke, 1992 *
Fungicide	2.5 mM	Geibel, M. 1994. Sensitivity of the Fungus Cytospora persoonii to the Flavonoids of Prunus cerasus. Phytochemistry. 38(3): 599-601. 1995.
Fungicide	ED50=50->100	Duke, 1992 *
Fungistat	IC34=200 uM	Duke, 1992 *
Histidine-Kinase-Inhibitor	IC50=110 uM	Medline (post 1990 searches filed in my computer)
Hypocholesterolemic	ED50=0.5 mg/kg	Duke, 1992 *
Immunostimulant	2-20 mg/kg orl mus	Duke, 1992 *
Lipase-Inhibitor	not available	Duke, 1992 *
MAO-Inhibitor	IC50=60-140 uM	Duke, 1992 *
MAO-Inhibitor	IC50=95	Duke, 1992 *
MDR-Inhibitor	200 uM	Castro, A. F., Altenberg, G. A. 1997. Inhibition of Drug Transport by Genistein in Multidrug-Resistant Cell Expressing P-Glycoprotein. Biochem Pharmacol, 53(1): 89-93.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Stellaria media	Shoot	not available	not available	not available	Duke, 1992 *
Stellaria media	Plant	not available	not available	not available	Abstract (See species file)
Stizolobium deeringianum	Stem	not available	not available	not available	Duke, 1992 *
Strongylodon macrobotrys	Leaf Diffusate	not available	8.0	-0.3	Duke, 1992 *
Teline sp	Leaf	not available	not available	not available	Duke, 1992 *
Teyleria koordersii	Leaf Diffusate	not available	10.0	0.0	Duke, 1992 *
Thermopsis fabacea	Leaf	not available	not available	not available	Duke, 1992 *
Thermopsis sp	Leaf	not available	not available	not available	Duke, 1992 *
Trifolium alexandrinum	Leaf	not available	not available	not available	Duke, 1992 *
Trifolium brachycalycinum	Leaf	1800.0	12900.0	1.2	Duke, 1992 *
Trifolium hybridum	Root	not available	not available	not available	Duke, 1992 *
Trifolium pratense	Flower	not available	19.0	not available	Duke, 1992 *
Trifolium pratense	Shoot	not available	not available	not available	Duke, 1992 *
Trifolium pratense	Stem	not available	62.0	not available	Duke, 1992 *
Trifolium pratense	Root	not available	10.0	-1.0	Duke, 1992 *
Trifolium pratense	Leaf	22.0	23.0	-1.0	Duke, 1992 *
Trifolium pratense	Plant	not available	not available	not available	Duke, 1992 *
Trifolium repens	Leaf	not available	not available	not available	Duke, 1992 *
Trifolium sp	Plant	not available	not available	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Trifolium subterraneum	Leaf	1110.0	13500.0	1.3	Duke, 1992 *