Chemical EMODIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

EMODIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
MMP-7-Inhibitor	not available	Duke, 1992 *
MMP-9-Inhibitor	not available	Duke, 1992 *
Mutagenic	not available	Duke, 1992 *
NO-Inhibitor	IC50=60.7 uM	Duke, 1992 *
Pesticide	not available	Duke, 1992 *
PGE2-Inhibitor	not available	Duke, 1992 *
Prostaglandin-Synthesis-Inhibitor	IC50=23 uM/ml	Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414.
Protein-Kinase-C-Inhibitor	IC50=25 uM	Duke, 1992 *
PTK-Inhibitor	IC50=19-37 uM	Duke, 1992 *
PTK-Inhibitor	10-100 uM	Duke, 1992 *
Purgative	ED50=>500 mg/kg orl mus	Duke, 1992 *
Styptic	not available	Duke, 1992 *
Topoisomerase-II-Inhibitor	1 mM	Muller, S. O., Eckert, I., Lutz, W. K., Stopper, H. 1996. Genotoxicity of the Laxative Drug Components Emodin, Aloe-emodin and Danthron in Mammalian Cells: Topoisomerase II Mediated? Mutat Res, 371: 165-173.
Topoisomerase-II-Inhibitor	IC50=7 uM/ml	Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414.
Trichomonicide	not available	Duke, 1992 *
Tyrosine-Kinase-Inhibitor	not available	Duke, 1992 *
Vasodilator	not available	Duke, 1992 *
Vasorelaxant	not available	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Alnus glutinosa	Bark	not available	not available	not available	Duke, 1992 *
Aloe vera	Plant	not available	not available	not available	Pakistan Encyclopedia Planta Medica. 1986.
Aloe vera	Leaf	not available	not available	not available	Saleem, R., Faizi, S., Deeba, F., Siddiqui, B. S., Qazi, M. H. 1997. Anthrones from Aloe barbadensis. Phytochemistry, 45(6): 1279-1282.
Boehmeria nivea	Root	not available	not available	not available	Duke, 1992 *
Cassia tora	Seed	not available	not available	not available	Duke, 1992 *
Fallopia japonica	Root	4000.0	6700.0	0.6	Duke, 1992 *
Frangula alnus	Bark	not available	not available	not available	Duke, 1992 *
Frangula purshiana	Plant	not available	not available	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Frangula purshiana	Bark	not available	not available	not available	Duke, 1992 *
Frangula purshiana	Tissue Culture	not available	not available	not available	Duke, 1992 *
Frangula purshiana	Bl	not available	not available	not available	Duke, 1992 *
Polygonum multiflorum	Tuber	not available	not available	not available	Duke, 1992 *
Polygonum multiflorum	Plant	not available	not available	not available	Duke, 1992 *
Polygonum multiflorum	Shoot	not available	not available	not available	Duke, 1992 *
Polygonum multiflorum	Bulb	not available	not available	not available	Duke, 1992 *
Polygonum multiflorum	Root	not available	not available	not available	Duke, 1992 *
Polygonum multiflorum	Rhizome	not available	not available	not available	Duke, 1992 *
Polygonum multiflorum	Leaf	not available	not available	not available	Duke, 1992 *
Rheum officinale	Root	3000.0	9000.0	1.3	Duke, 1992 *
Rheum officinale	Plant	not available	not available	not available	Duke, 1992 *