Chemical 6-GINGEROL | Dr. Duke's Phytochemical and Ethnobotanical Databases

Dr. Duke's Phytochemical and Ethnobotanical Databases

U.S. Department of Agriculture

Chemical ID

6GINGEROL

Ubiquitous

No

List of known dosages
Dosage	Reference
LD90=62 ug/ml
LD50=25-50 (inv mus)
LD50=250-687 (orl mus)
LD50=25.5 (inv mus)	Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
LD50=58.1 (ipr mus)	Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
LD50=250 (orl mus)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Hypertensive	0.5-1 mg/kg	Duke, 1992 *
Hypotensive	1-100 ug/kg	Duke, 1992 *
Larvicide	LD90=62 ug/ml	Duke, 1992 *
Mutagenic	not available	J. Drug. Dev. (Vol. 6=1993) e.g. Mustafa, T., Srivastava, K.C., and Jensen, K.B. 1993. Drug Development Report (9): Pharmacology of Ginger, Zingiber officinale. J. Drug. Dev. 6(1): 25-39.
Nematicide	LD90=62 ug/ml	Duke, 1992 *
Prostaglandin-Synthesis-Inhibitor	1 mM (60.7% inhibition)	Duke, 1992 *
Sedative	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Thermogenic	10 uM rat	Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Zingiber officinale	Root Essent. Oil	not available	not available	not available	Duke, 1992 *
Zingiber officinale	Rhizome Essent. Oil	not available	not available	not available	Duke, 1992 *
Zingiber officinale	Rhizome	130.0	7138.0	not available	Duke, 1992 *
Zingiber officinale	Essential Oil	not available	not available	not available	Duke, 1992 *
Zingiber officinale	Root	not available	not available	not available	Duke, 1992 *