Chemical 1,8-CINEOLE | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

18CINEOLE

Ubiquitous

List of known dosages
Dosage	Reference
LD50=2,480 (orl rat)	Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
LD50=3,480 mg/kg
LD50=>5,000 (dml rbt)
LD100=1,000 ug/ml
LD50=100 mg/kg (ims mus)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
(-)-Chronotropic	87 nl/ml	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
(-)-Inotropic	87 nl/ml	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Acaricide	LC100=6 uM	Duke, 1992 *
Allelopathic	not available	Duke, 1992 *
Allergenic	not available	Duke, 1992 *
Anesthetic	not available	Duke, 1992 *
Anthelmintic	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiacetylcholinesterase	IC50=41 ug/ml	Duke, 1992 *
Antiallergic	not available	J. Food Hyg. Soc. Jap. 33(6): 569.
Antibacterial	50 ppm	Duke, 1992 *
Antibronchitic	not available	Duke, 1992 *
Anticariogenic	not available	Duke, 1992 *
Anticatarrh	not available	Martindale's 29th
Anticholinesterase	IC50=50-70	Duke, 1992 *
Antifatigue	not available	Duke, 1992 *
Antihalitosic	not available	American Health, 12(4): 17, 1993.
Antiinflammatory	not available	Duke, 1992 *
Antilaryngitic	not available	Duke, 1992 *
Antinociceptive	not available	Duke, 1992 *
Antipharyngitic	not available	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Turnera diffusa	Leaf	550.0	1100.0	-0.4	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Umbellularia californica	Plant	2340.0	9360.0	2.1	Duke, 1992 *
Vaccinium corymbosum	Fruit	not available	not available	not available	Duke, 1992 *
Valeriana officinalis	Leaf	85.0	1660.0	-0.3	Duke, 1992 *
Vetiveria zizanioides	Root	not available	15.0	not available	Duke, 1992 *
Vitex agnus-castus	Flower	not available	not available	not available	Duke, 1992 *
Vitex agnus-castus	Fruit	600.0	4225.0	-0.2	Duke, 1992 *
Vitex agnus-castus	Leaf	not available	115.0	-0.5	Ekundayo, O., Laakso, I., Holopainen, M., Hiltunen, R., Oguntimein, B., and Kauppinen, V. 1990. The Chemical Composition and Antimicrobial Activity of the Leaf Oil of Vitex agnus-castus L. J. Essential Oil Research, 2: 115-119.
Zea mays	Silk Stigma Style	not available	not available	not available	Duke, 1992 *
Zingiber officinale	Rhizome	not available	490.0	-0.8	Duke, 1992 *
Zingiber officinale	Rhizome Essent. Oil	26000.0	100000.0	not available	Duke, 1992 *