An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. 1,8-CINEOLE

1,8-CINEOLE

Chemical ID
18CINEOLE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=2,480 (orl rat) Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
LD50=3,480 mg/kg
LD50=>5,000 (dml rbt)
LD100=1,000 ug/ml
LD50=100 mg/kg (ims mus) Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Download these results as:
CSV
EXCEL
PDF
List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
(-)-Chronotropic 87 nl/ml Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
(-)-Inotropic 87 nl/ml Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Acaricide LC100=6 uM *
Allelopathic *
Allergenic *
Anesthetic *
Anthelmintic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiacetylcholinesterase IC50=41 ug/ml *
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Antibacterial 50 ppm *
Antibronchitic *
Anticariogenic *
Anticatarrh Martindale's 29th
Anticholinesterase IC50=50-70 *
Antifatigue *
Antihalitosic American Health, 12(4): 17, 1993.
Antiinflammatory *
Antilaryngitic *
Antinociceptive *
Antipharyngitic *
Download these results as:
CSV
EXCEL
PDF
List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Pycnanthemum incanum Shoot 33.0 76.0 -0.1 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum loomisii Shoot 17853.0 26040.0 0.2 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum montanum Shoot 21.0 720.0 -0.1 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum muticum Shoot 1.0 50.0 -0.1 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum pilosum Flower 10.0 35.0 -0.4 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum pilosum Leaf 10.0 35.0 -0.5 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum pycnanthemoides Shoot 39.0 116.0 -0.1 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum setosum Shoot 20.0 7099.0 0.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum tenuifolium Shoot 1.0 1100.0 -0.1 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum torreyi Shoot 10.0 -0.1 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum verticillatum Shoot 42.0 -0.1 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Pycnanthemum virginianum Shoot 6.0 58.0 -0.1 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Ravensara aromatica Bark 44.0 -1.0 *
Ravensara aromatica Leaf 20.0 -0.5 *
Ribes nigrum Fruit List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Rosmarinus eriocalyx Shoot 380.0 705.0 -0.1 Soriano Cano, M.C., Sotomayor Sanchez, J.A., Sanchez Gomez, P. and Garcia Vallejo, M.C. 1993. Essential Oils of the Rosmarinus eriocalyx-tomentosus Complex in Southeast Spain. J. Ess. Oil Res. 5: 243-246.
Rosmarinus eriocalyx Shoot 380.0 705.0 -0.1 Soriano Cano, M.C., Sotomayor Sanchez, J.A., Sanchez Gomez, P. and Garcia Vallejo, M.C. 1993. Essential Oils of the Rosmarinus eriocalyx-tomentosus Complex in Southeast Spain. J. Ess. Oil Res. 5: 243-246.
Rosmarinus officinalis Shoot 630.0 1360.0 -0.1 Soriano Cano, M.C., Sotomayor Sanchez, J.A., Sanchez Gomez, P. and Garcia Vallejo, M.C. 1993. Essential Oils of the Rosmarinus eriocalyx-tomentosus Complex in Southeast Spain. J. Ess. Oil Res. 5: 243-246.
Rosmarinus officinalis Leaf 0.0 -0.5 Soliman, F.M., El-Kashoury, M.M., Fathy, M.M. and Gonaid, M.H. 1994. Analysis and Biological Activity of the Essential Oil of Rosmarinus officinalis L. from Egypt. Flavour and Fragrance J. 9: 29-33.
Rosmarinus officinalis Leaf 0.0 -0.5 Soliman, F.M., El-Kashoury, M.M., Fathy, M.M. and Gonaid, M.H. 1994. Analysis and Biological Activity of the Essential Oil of Rosmarinus officinalis L. from Egypt. Flavour and Fragrance J. 9: 29-33.