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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Topoisomerase-I-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
XESTOQUINONE IC50=0.15 ug/ml Bae, M. A., Tsuji, T., Kondo, K., Hirase, T., Ishibashi, M., Shigemori, H., Kobayashi, J. I. 1993. Inhibition of Mammalian Topoisomerase I by Xestoquinone and Halenaquinone. Biosci. Biotech. Biochem., 57: 330-331.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Lygos raetum 1 0
Maackia amurensis 1 0
Maclura pomifera Osage-Orange; Hedge Apple 5 29, 724
Macroptylium atropurpureum 1 0
Macroptylium bracteatum 1 10
Macroptylium lathyroides 1 0
Macroptylium martii 1 0
Macrotyloma axillare 1 0
Macrotyloma uniflora 1 0
Magnolia denudata Hsin-I; Xin-Yi 2 0
Magnolia kobus Hsin-I; Xin-Yi 2 0
Magnolia officinalis Chinese Magnolia; Hou Pu; Magnolia-Bark 2 0
Malus domestica Apple 6 610.5
Mangifera indica Mango 3 90, 000
Maranta arundinacea Arrowroot; Bermuda Arrowroot 1 0
Marrubium vulgare Horehound; White Horehound 4 0
Matricaria recutita Annual Camomile; German Camomile; Wild Camomile 4 25, 200
Medicago sativa Alfalfa; Lucerne 8 140
Melaleuca leucadendra Cajeput 2 0
Melia azedarach Chinaberry 2 0