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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Thermogenic

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(+)-PSEUDOEPHEDRINE < (-)-EPHEDRINE Bukowiecki, L., Jahjah, L., Follea, N. 1982. Ephedrine, a Potential Slimming Drug, Directly Stimulates Thermogenesis in Brown Adipocytes Via Beta-Adrenoreceptors. Int J Obesity, 6: 343-350.
(-)-EPHEDRINE > (+)-pseudoephedrine & (-)-pseudoephedrine Bukowiecki, L., Jahjah, L., Follea, N. 1982. Ephedrine, a Potential Slimming Drug, Directly Stimulates Thermogenesis in Brown Adipocytes Via Beta-Adrenoreceptors. Int J Obesity, 6: 343-350.
(-)-EPIGALLOCATECHIN-GALLATE *
(-)-PSEUDOEPHEDRINE < (-)-EPHEDRINE Bukowiecki, L., Jahjah, L., Follea, N. 1982. Ephedrine, a Potential Slimming Drug, Directly Stimulates Thermogenesis in Brown Adipocytes Via Beta-Adrenoreceptors. Int J Obesity, 6: 343-350.
10-GINGEROL 60 uM rat Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.
6-GINGEROL 10 uM rat Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.
6-SHOGAOL 20 uM rat Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.
8-GINGEROL 20 uM rat Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.
8-SHOGAOL 20 uM rat Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.
CAPSAICIN 0.7 mg/kg ims rat Yoshida, T., Yoshioka, K., Wakabayashi, Y., Nishioka, H., Kondo, M. 1988. Effects of Capsaicin and Isothiocyanate on Thermogensis of Interscapular Brown Adipose Tissue in Rats. J Nutr Sci Vitaminol, 34(6): 587-594.
CATHINONE 15 mg/kg igs rat Tariq, M., Islam, M. W., Al-Meshal, I. A., El-Feraly, F. S., Ageel, A. M. 1989. Comparative Study of Cathinone and Amphetamine on Brown Adipose Thermogenesis. Life Sciences, 44(14): 951-955.
CONJUGATED-LINOLEIC-ACID Newman, R. A., Lansky, E. P., with Block, M. L. 2007. Pomegranate - The Most Medicinal Fruit. Basic Health Publications, Laguna Beach, CA. 120 pp.
ISOTHIOCYANATE 3 ppm Yoshida, T., Yoshioka, K., Wakabayashi, Y., Nishioka, H., Kondo, M. 1988. Effects of Capsaicin and Isothiocyanate on Thermogensis of Interscapular Brown Adipose Tissue in Rats. J Nutr Sci Vitaminol, 34(6): 587-594.
PHYSOSTIGMINE 50 ug/kg ivn rat Matthew, C. B., Francesconi, R. P., Hubbard, R. W. 1992. Physostigmine: Dose-Response Effects on Endurance and Thermoregulation During Exercise. Life Sciences, 50(1): 39-44.
PIPERINE 5 mg/man Sabinsa: A series of well documented proprietary PR booklets,
e.g.Sabinsa Corps. 1998. Bronchial Asthma - Its etiology and control with traditional herbal extracts. Sabinsa Corporation. Piscataway, NJ. 49 pp.
SALICYLIC-ACID 130 ppm *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Calea zacatechichi Bitter Grass; Dog's Grass; Mexican Calea 1 0
Calendula officinalis Calendula; Pot-Marigold 1 0.6800000071525574
Camellia sinensis Tea 2 0
Cananga odorata Cananga; Ylang-Ylang 1 0
Capsicum annuum Bell Pepper; Green Pepper; Cherry Pepper; Sweet Pepper; Cone Pepper; Paprika 1 3, 831, 540
Capsicum frutescens Cayenne; Chili; Tabasco; Hot Pepper; Spur Pepper; Red Chili 1 107, 430
Centaurea cyanus Cornflower; Bachelor's Button 1 0
Cimicifuga racemosa Black Cohosh; Black Snakeroot 1 0
Cinnamomum aromaticum Cassia; Cassia Bark; Cassia Lignea; Chinese Cassia; Chinese Cinnamon; China Junk Cassia; Saigon Cinnamon; Zimtcassie (Ger.); Canela de la China (Sp.); Canelero chino (Sp.); Chinazimt (Ger.); Chinesischer Zimtbaum (Ger.); Kashia-Keihi (Jap.); Canelle de Cochinchine (Fr.); Cannelier Casse (Fr.); Cannelier de Chine (Fr.) 1 0
Colchicum autumnale Autumn Crocus; Meadow Saffron 1 0
Cucurbita pepo Pumpkin 1 0
Dipteryx odorata Tonka Bean; Dutch Tonka Bean 1 0
Ephedra sinica Ma Huang; Chinese Ephedra 2 57, 000
Filipendula ulmaria Meadowsweet; Queen Of The Meadow 1 32
Fragaria spp Strawberry 1 0
Gloriosa superba Glory Lily 1 0
Glycine max Soybean 1 0
Glycyrrhiza glabra Commom Licorice; Licorice; Smooth Licorice; Licorice-Root 1 4, 536
Gossypium sp Cotton 1 0
Hedeoma pulegioides American Pennyroyal 1 0