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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Biological Activity Thermogenic

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(+)-PSEUDOEPHEDRINE < (-)-EPHEDRINE Bukowiecki, L., Jahjah, L., Follea, N. 1982. Ephedrine, a Potential Slimming Drug, Directly Stimulates Thermogenesis in Brown Adipocytes Via Beta-Adrenoreceptors. Int J Obesity, 6: 343-350.
(-)-EPHEDRINE > (+)-pseudoephedrine & (-)-pseudoephedrine Bukowiecki, L., Jahjah, L., Follea, N. 1982. Ephedrine, a Potential Slimming Drug, Directly Stimulates Thermogenesis in Brown Adipocytes Via Beta-Adrenoreceptors. Int J Obesity, 6: 343-350.
(-)-EPIGALLOCATECHIN-GALLATE *
(-)-PSEUDOEPHEDRINE < (-)-EPHEDRINE Bukowiecki, L., Jahjah, L., Follea, N. 1982. Ephedrine, a Potential Slimming Drug, Directly Stimulates Thermogenesis in Brown Adipocytes Via Beta-Adrenoreceptors. Int J Obesity, 6: 343-350.
10-GINGEROL 60 uM rat Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.
6-GINGEROL 10 uM rat Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.
6-SHOGAOL 20 uM rat Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.
8-GINGEROL 20 uM rat Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.
8-SHOGAOL 20 uM rat Eldershaw, T. P. D., Colquhoun, E. Q., Dora, K. A., Peng, Z. C., Clark, M. G. 1992. Pungent Principles of Ginger (Zingiber officinale) are Thermogenic in the Perfused Rat Hindlimb. Int J. Obesity, 16: 755-763.
CAPSAICIN 0.7 mg/kg ims rat Yoshida, T., Yoshioka, K., Wakabayashi, Y., Nishioka, H., Kondo, M. 1988. Effects of Capsaicin and Isothiocyanate on Thermogensis of Interscapular Brown Adipose Tissue in Rats. J Nutr Sci Vitaminol, 34(6): 587-594.
CATHINONE 15 mg/kg igs rat Tariq, M., Islam, M. W., Al-Meshal, I. A., El-Feraly, F. S., Ageel, A. M. 1989. Comparative Study of Cathinone and Amphetamine on Brown Adipose Thermogenesis. Life Sciences, 44(14): 951-955.
CONJUGATED-LINOLEIC-ACID Newman, R. A., Lansky, E. P., with Block, M. L. 2007. Pomegranate - The Most Medicinal Fruit. Basic Health Publications, Laguna Beach, CA. 120 pp.
ISOTHIOCYANATE 3 ppm Yoshida, T., Yoshioka, K., Wakabayashi, Y., Nishioka, H., Kondo, M. 1988. Effects of Capsaicin and Isothiocyanate on Thermogensis of Interscapular Brown Adipose Tissue in Rats. J Nutr Sci Vitaminol, 34(6): 587-594.
PHYSOSTIGMINE 50 ug/kg ivn rat Matthew, C. B., Francesconi, R. P., Hubbard, R. W. 1992. Physostigmine: Dose-Response Effects on Endurance and Thermoregulation During Exercise. Life Sciences, 50(1): 39-44.
PIPERINE 5 mg/man Sabinsa: A series of well documented proprietary PR booklets,
e.g.Sabinsa Corps. 1998. Bronchial Asthma - Its etiology and control with traditional herbal extracts. Sabinsa Corporation. Piscataway, NJ. 49 pp.
SALICYLIC-ACID 130 ppm *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Punica granatum Pomegranate; Grenadier (Fr.); Granatapfelbaum (Ger.); Granatapfelstrauch (Ger.); Zakuro (Jap.); Romanzeiro (Port.); Granado (Sp.); Mangrano (Sp.) 1 0
Ribes rubrum Red Currant; White Currant 1 0
Rosa multiflora Multiflora Rose 1 0
Rubus idaeus Red Raspberry; Raspberry 1 0
Salix alba White Willow 1 0
Salvia officinalis Sage 1 0
Solidago gigantea Early Goldenrod 1 35
Stachytarpheta cayennensis Verbena 1 0
Taxus baccata Common Yew 1 4
Trifolium pratense Red Clover; Purple Clover; Peavine Clover; Cowgrass 1 0
Triticum aestivum Wheat 1 4
Ulmus rubra Slippery Elm; Red Elm 1 46
Vaccinium myrtillus Bilberry; Whortleberry; Dwarf Bilberry 1 0
Vaccinium vitis-idaea Cowberry; Lingen; Lingonberry 1 0
Vanilla planifolia Vanilla; Bourbon Vanilla 1 0
Viburnum prunifolium Black Haw 1 0
Viola odorata Common Violet; Sweet Violet 1 0
Viola tricolor Pansy; Wild Violet 1 0
Vitis vinifera Grape; European Grape; Wine Grape; Grapevine; Vigne Vinifere (Fr.); Weinrebe (Ger.); Parra (Sp.); Vid (Sp.) 1 0
Xylopia aethiopica Ethiopian Pepper; Guinea Pepper; Negro Pepper; Spice Tree; Mohrenpfeffer (Ger.); Maniguete (Sp.); Pimienta de Guinea (Sp.) 1 63, 700