An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. Quinone-Reductase-Inducer

Quinone-Reductase-Inducer

Download these results as:
CSV
EXCEL
PDF
List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
PROGOITRIN 15 uM Tawfig,N. Heaney,R.K.,Plumb,J.A.,Fenwick,G.R.,Musk,S.R.R.,Williamson,G.1995. Dietary Glucosinolates as Blocking Agents Against Carcinogenesis: Glucosinolate Breakdown Products Assessed Induction of Quinone Reductase Activity I.Carcinogenesis 16(5)119-1194
PURPURIN IC50>50.7 uM *
PYROCATECHOL Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
QUERCETIN 6 uM Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
QUERCETIN 13 uM *
QUERCETIN-4'-GLUCOSIDE 30 uM Willaimason, G., Plumb, G. W., Uda, Y., Price, K. R., Rhodes, M. J. C. 1996. Dietary Quercetin Glycosides: Antioxidant Activity and Induction of the Anticarcinogenic Phase II Marker Enzyme Quinone Reductase in Hepalclc7 Cells. Carcinogenesis 17(11): 2385.
RESVERATROL ED100=21 uM *
RHAMNETIN Yannai, S., Day, A. J., Williamson, G., Rhodes, M. J. C. 1998. Characterization of Flavonoids as Monofunctional or Bifunctional Inducers of Quinone Reductase in Murine Hepatoma Cell Lines. Food Chem Toxicol, 36(8): 623-630.
SINIGRIN 15 uM Tawfig,N. Heaney,R.K.,Plumb,J.A.,Fenwick,G.R.,Musk,S.R.R.,Williamson,G.1995. Dietary Glucosinolates as Blocking Agents Against Carcinogenesis: Glucosinolate Breakdown Products Assessed Induction of Quinone Reductase Activity I.Carcinogenesis 16(5)119-1194
SPIRAEOSIDE Yannai, S., Day, A. J., Williamson, G., Rhodes, M. J. C. 1998. Characterization of Flavonoids as Monofunctional or Bifunctional Inducers of Quinone Reductase in Murine Hepatoma Cell Lines. Food Chem Toxicol, 36(8): 623-630.
SULFORAPHANE IC50=11 uM *
SULFORAPHANE 15 uM gas mus Cho, C. G., Posner, G. H., Talalay, P., Zhang, Y. S. 1995. Chemoprotective Isothiocyanates. Patent-US-5,411,986: 1-22.
SULFORAPHANE 15 uM igs mus Zhang, Y., Talalay, P., Cho, C. G., Posner, G. H. 1992. A Major Inducer of Anticarcinogenic Protective Enzymes from Broccoli: Isolation and Elucidation of Structure. Proc. Nat. Acad. Sci., 89: 2399-2403.
SULFORAPHANE IC50=5-0.03 ug/ml Lee, S. K., Song, Y., Mata-Greenwood, E., Kelloff, G. J., Steele, V. E., Pezzuto, J. M. 1999. Modulation of in vitro Biomarkers of the Carcinogenic Process by Chemopreventive Agents. Anticancer Res., 19: 35-44.
SULPHORAPHANE ED50=0.43 uM *
TAMARIXETIN Yannai, S., Day, A. J., Williamson, G., Rhodes, M. J. C. 1998. Characterization of Flavonoids as Monofunctional or Bifunctional Inducers of Quinone Reductase in Murine Hepatoma Cell Lines. Food Chem Toxicol, 36(8): 623-630.
TRANS-CHALCONE Lee, S. K., Song, Y., Mata-Greenwood, E., Kelloff, G. J., Steele, V. E., Pezzuto, J. M. 1999. Modulation of in vitro Biomarkers of the Carcinogenic Process by Chemopreventive Agents. Anticancer Res., 19: 35-44.
URSOLIC-ACID 5 ug/ml Lee, S. K., Song, Y., Mata-Greenwood, E., Kelloff, G. J., Steele, V. E., Pezzuto, J. M. 1999. Modulation of in vitro Biomarkers of the Carcinogenic Process by Chemopreventive Agents. Anticancer Res., 19: 35-44.
WITHAPHYSACARPIN ED50=0.43 uM Kennelly, E. J., Gerhauser, C., Song, L. L., Graham, J. G., Beecher, C. W. W., Pezzuto, J. M., Kinghorn, A. D. 1997. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos). J. Agr. & Food Chem., 45(10): 3771-3777.
ZEAXANTHIN Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Download these results as:
CSV
EXCEL
PDF
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Abelmoschus esculentus Okra 2 0
Abelmoschus moschatus Ambrette; Musk Okra; Tropical Jewel Hibiscus; Muskmallow 2 0
Abutilon theophrasti Velvet Leaf; Butterprint; Indian-Mallow; Abutilon-Hemp 3 0
Acacia catechu Black Cutch; Catechu 3 0
Acacia farnesiana Cassie; Huisache; Sweet Acacia; Opopanax; Popinac 2 0
Acacia leucophloea Pilang Bast 1 0
Acacia nilotica Babul 2 0
Acacia senegal Gum Arabic; Gum Arabic Tree; Kher; Senegal Gum; Sudan Gum Arabic 2 0
Acacia tortilis Umbrella Thorn 1 0
Acalypha indica Cancer Herb; Indian Acalypha; Copperleaf; Indian Nettle; Three-Seeded-Mercury 1 0
Achillea millefolium Yarrow; Milfoil 4 0
Acinos suaveolens 3 899.8999996185303
Acorus calamus Sweetflag; Calamus; Flagroot; Myrtle Flag; Sweet Calamus; Sweetroot 1 0
Actinidia chinensis Kiwi 3 9
Adenocarpus decorticans 1 0
Adenocarpus foliolosus 1 0
Aesculus hippocastanum Horse Chestnut 4 0
Agathosma betulina Buchu; Honey Buchu; Mountain Buchu 1 0
Ageratum conyzoides Mexican ageratum 2 0
Aglaonema commutatum Aglaonema aroid 1 0