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Biological Activity Quinone-Reductase-Inducer

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(+)-PURPURIN ED50=5.6 uM Duke, 1992 *
(+)-TEPHROPURPURIN IC50 13.4 uM Duke, 1992 *
(+)-TEPHROPURPURIN ED50=0.15 uM Duke, 1992 *
(-)-3-HYDROXY-4-METHOXY-8,9-METHYLENEDIOXYPTEROCARPAN IC50=>63.7 uM Duke, 1992 *
(-)-MAACKIAIN ED50=8.8 uM Duke, 1992 *
(-)-MEDICARPIN ED50=13.7 uM Duke, 1992 *
(1'S)-1'-ACETOXYCHAVICOL-ACETATE not available Duke, 1992 *
24,25-DIHYDROWITHANOLIDE-D ED50=0.7 uM Kennelly, E. J., Gerhauser, C., Song, L. L., Graham, J. G., Beecher, C. W. W., Pezzuto, J. M., Kinghorn, A. D. 1997. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos). J. Agr. & Food Chem., 45(10): 3771-3777.
3-METHOXY-2,3-DIHYDROWITHAPHYSACARPIN ED50=7.8 uM Kennelly, E. J., Gerhauser, C., Song, L. L., Graham, J. G., Beecher, C. W. W., Pezzuto, J. M., Kinghorn, A. D. 1997. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos). J. Agr. & Food Chem., 45(10): 3771-3777.
4',7-DIHYDROXY-3',5'-DIMETHOXYISOFLAVONE ED50=17.2 uM Duke, 1992 *
4-HYDROXY-GLUCOBRASSICIN 100 uM Fahey, J. W., Zhang, Y., Talalay, P. 1997. Broccoli Sprouts: An Exceptionally Rich Source of Inducers of Enzymes that Protects Against Chemical Carcinogens. Proc. Nat. Acad. Sci., 94: 10367-10372.
6-METHYL-SULFINYL-HEXYL-ISOTHIOCYANATE not available Fuke, Y., Haga, Y., Ono, H., Nomura, T., Ryoyama, K. 1998. Anti-Carcinogenic Activity of 6-methylsulfinylhexyl isothiocyanate, an Active Anti-Proliferative Principle of Wasabi (Eutrema wasabi Maxim.). Cytotechnology, 25: 197-203.
7,4'-DIHYDROXY-3',5'-DIMETHOXYISOFLAVONE IC50>63.7 uM Duke, 1992 *
ALYSSIN 0.95 uM Duke, 1992 *
APIGENIN 20 uM Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
AURAPTENE 100 ppm Duke, 1992 *
AURAPTENE 400 mg/kg igs rat Tanaka,T. et al.1998.Citrus Auraptene Exerts Dose-Dependent Chemopreventive Activity in Rat Large Bowel Tumorigenesis:The Inhibition Correlates with Suppression of Cell Proliferation & Lipid Peroxidation & with Induction of Phase II-. Cancer Res.58:2550.
BAICALIN not available Duke, 1992 *
BERTEROIN 1.7 uM Zhang, Y., Talalay, P., Cho, C. G., Posner, G. H. 1992. A Major Inducer of Anticarcinogenic Protective Enzymes from Broccoli: Isolation and Elucidation of Structure. Proc. Nat. Acad. Sci., 89: 2399-2403.
BIS-DEMETHOXYCURCUMIN 11.9 uM Singletary, K., et al. 1998. Effect of the Beta-Diketones Diferoloylmethane (Curcumin) and Dibenzoylmethane on Rat Mammary DNA Adducts and Tumors Induced by 7,12-dimethylbenz(A)anthracene. Carcinogenesis, 19(6): 1039-1043.
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Duchesnea indica False Strawberry; Indian Strawberry; Mock Strawberry 2 943.8000000715256
Dunbaria villosa not available 1 13
Echinacea angustifolia Echinacea; Narrow Leaf Echinacea; Narrow Leaf Purple-Coneflower 4 0
Echinacea purpurea Echinacea; Eastern Purple-Coneflower; Purple-Coneflower 1 0
Echinacea spp Coneflower; Echinacea 3 0
Echinospartium horridum not available 1 0
Elaeagnus angustifolia Russian Olive; Silver Berry 4 0
Elaeagnus pungens Thorny Silver Berry 1 0
Ephedra gerardiana Pakistani Ephedra 1 0
Ephedra sinica Ma Huang; Chinese Ephedra 3 0
Equisetum arvense Field Horsetail; Horsetail 4 0
Erinacea anthyllis not available 1 0
Eriobotrya japonica Loquat 3 955.5999755859375
Eriosema glomeratum not available 1 6
Eriosema nutans not available 1 7
Eriosema psoraleoides not available 1 6
Eruca sativa Achnef (Berber; BOU); Garden Rocket (Eng.; USN); Rocket Salad (Eng.; USN); Rugula (Eng.; USN); Salad Rocket (Eng.; USN); Roquette (Eng.; Fr.; BOU); Olrauke (Ger.; USN); Ruke (Ger.; USN); Senfrauke (Ger.; USN); Jamba (India); Taramira (India; Nwp.); Rucola (It.; Malta; Sp.); Rabano silvestre (It.; Port.;); Oruga comun (Sp.; USN); Roqueta (Sp.; USN); Ackerrauke (Ger.; MAD); Ai'afein (Arab.; BOU); Ai'sha (Arab.; BOU); Aruca (Malta; KAB); Arugula (Eng.; FAC; USN); Assu (Punjab; SKJ); Baglet (Arab.; BOU); Bhutaghna (Sansk.; SKJ); Bimbata (Sansk.; KAB); Bou kahli (Arab.; BOU); Chara (Kumaon; DEP); Daradharsha (Sansk.; KAB); Djerdjir (Arab.; BOU); Dua (Kumaon; DEP); Duan (Nwp; KAB); Eihukan (Iran; NAD); Eruca (Malta; KAB); Euzomon (Greece; EB54:155); Gargir (Arab.; Hebrew; BOU); Gery (Arab.; BOU); Grahagna (Sansk.; KAB); Horf (Arab.; BOU); Izgin (Turkey; EB54:155); Jambeh (Iran; DEP; KAB); Jambeho (Sind.; KAB); Jambho (Sind.; DEP); Jamnia (Punjab; DEP); Kadamba (Sansk.; KAB); Kadambaka (Sansk.; KAB); Kerkas (Arab.; BOU); Kibana suzushiro (Jap.; TAN); Lalu (Nwp.; KAB); Lamba (India; USN); Mandao (Afg.; DEP; KAB); Mulai (Loralai; KAB); Oroth (Bible; EB52:394); Piao erh ts'ai (Chi.; TAN); Rajakshavaka (Sansk.; KAB); Rajika (Sansk.; KAB); Rakshitaphala (Sansk.; KAB); Rawk (Arab.; BOU); Rocket (Eng.; BOU); Roquette cultivee (Fr.; KAB); Roquette des jardins (Fr.;KAB); Roquette vraie (Fr.; BOU); Rouka (Arab.; BOU); Ruca (Catalan; KAB); Rucheta (Malta; KAB); Sahwan (Nwp.; KAB); Sarishapa (Sansk.; KAB); Sarshapa (Sansk.; KAB); Sfed sarson (Hindi; MPI); Shiltam (Arab.; BOU); Shwetsursha (Bengal; SKJ); Siddartha (Sansk.; DEP; SKJ); Sidhaprayojana (Sansk.; KAB); Sidharta (Sansk.; KAB); Suffed shorshi (Bengal; DEP); Tanakfail (Berber; BOU); Tantubha (Sansk.; KAB); Tantuka (Sansk.; KAB); Tara (Nwp.; Punjab; KAB; SKJ); Thorfel (Berber; BOU); Tira (Nwp.; DEP; KAB); Tuverika (Sansk.; KAB); Ugragandha (Sansk.; KAB) 1 0
Erythrina crista-galli Cockspur Coral Tree 1 0
Erythrina sp not available 1 0
Erythroxylum coca Coca 1 0