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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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COX-1-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=10 uM/ Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
N-2'-METHYL-BUTYL-DECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-DODECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-HEXADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-TETRADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PELLITORINE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PINOSTROBIN IC36=100 ug/ml *
PTEROSTILBENE IC50=20 uM *
PUNICIC-ACID *
RESVERATROL 50 uM/ Jang, M. S., Pezzuto, J. M. 1998. Resveratrol Blocks Eicosanoid Production and Chemically-Induced Cellular Transformation: Implication for Cancer Chemoprevention. Pharm Biol Suppl, 36: 28-34.
RESVERATROL ED50=15 uM *
ROSMARINIC-ACID IC58=1,000 uM *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Eucalyptus globulus Blue Gum; Eucalypt; Tasmanian Bluegum 2 0
Eucalyptus wandoo 1 0
Eugenia brasiliensis Brazil Cherry; Grumichama 1 4.800000190734863
Eugenia floribunda Black rumberry; Camu-camu arbol; Camu-camu negro 1 0
Eugenia uniflora Pitanga; Surinam Cherry 1 202
Eupatorium perfoliatum Boneset 1 0
Euphrasia officinalis Eyebright 2 73
Fagopyrum esculentum Buckwheat 2 0
Fallopia japonica Japanese Knotweed; Giant Knotweed; Mexican Bamboo; Hu-Zhang 2 408
Ficus carica Fig; Figuier Commun (Fr.); Echte Feige (Ger.); Feigenbaum (Ger.); Fico (Ital.); Figueira (Port.); Higo (Sp.); Higuera Comun (Sp.) 3 128
Foeniculum vulgare Fennel 2 2, 242.899999976158
Fragaria spp Strawberry 2 7
Frangula alnus Buckthorn 2 0
Frangula purshiana Cascara Sagrada; Cascara Buckthorn 1 92
Fucus vesiculosus Bladderwrack; Kelp 2 80
Garcinia mangostana Mangosteen; Mangostin 1 0
Gentiana lutea Yellow Gentian; Gentian 1 78
Geranium thunbergii Gennoshiouko; Oriental Geranium 1 0
Ginkgo biloba Ginkgo; Maidenhair Tree 4 286
Glechoma hederacea Alehoof 2 26, 000