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Biological Activity COX-1-Inhibitor

List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=0.5 uM/ Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
N-2'-METHYL-BUTYL-DECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-DODECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-HEXADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-TETRADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PELLITORINE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PINOSTROBIN IC36=100 ug/ml Duke, 1992 *
PTEROSTILBENE IC50=20 uM Duke, 1992 *
PUNICIC-ACID not available Duke, 1992 *
RESVERATROL ED50=15 uM Duke, 1992 *
RESVERATROL 50 uM/ Jang, M. S., Pezzuto, J. M. 1998. Resveratrol Blocks Eicosanoid Production and Chemically-Induced Cellular Transformation: Implication for Cancer Chemoprevention. Pharm Biol Suppl, 36: 28-34.
ROSMARINIC-ACID IC58=1,000 uM Duke, 1992 *
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Colocasia esculenta Taro 1 298.80000001192093
Commiphora myrrha Myrrh; African Myrrh; Herabol Myrrh; Somali Myrrh; Myrrhe (Fr., Ger.); Mirra (Sp. It.) 1 13, 800
Conyza canadensis Butterweed; Hogweed; Horseweed 1 0
Corchorus olitorius Jew's Mallow; Mulukiya; Nalta Jute 1 1, 485
Coriandrum sativum Coriander; Chinese Parsley; Cilantro 2 684
Corylus avellana English Filbert; European Filbert; European Hazel; Hazel; Cobnut 1 2.0000000298023224
Crataegus laevigata Hawthorn; English Hawthorn; Whitethorn; Woodland Hawthorn 5 20
Crataegus monogyna Hawthorn; English Hawthorn 2 0
Crataegus rhipidophylla Hawthorn 4 5.400000095367432
Crescentia alata Jicaro 1 0.20000000298023224
Crocus sativus Saffron 2 0
Croton eluteria Cascarilla 1 0
Croton lechleri Sangre de Drago; Sangre de Grado; Sangre de Dragon; Dragons Blood 2 0
Croton tiglium Purging Croton 1 250
Cucumis melo Cantaloupe; Melon; Muskmelon; Netted Melon; Persian Melon; Nutmeg Melon 2 54, 726
Cucumis sativus Cucumber 1 8
Cucurbita pepo Pumpkin 2 1, 152.5
Cucurbita spp Summer Squash 2 161.89999997615814
Cuminum cyminum Cumin 2 16
Curcuma longa Turmeric; Indian Saffron 2 8, 436