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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antiplasmodial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
ISOFEBRIFUGINE IC50=0.002-0.003 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOIGUESTEROL IC50=0.023-0.54 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOMELDENIN IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOSTRYCHNINE IC50=14->20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOSUNGUCINE IC50=0.3-1.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOTETRANDRINE IC50=100 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
JATRORRHIZINE IC50=0.42-1.61 ug/ml *
JATRORRHIZINE-CHLORIDE IC50= 0.36ug/ml *
KORUNDAMINE-A IC50=1.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
KORUPENSAMINE-A IC50=0.02-0.6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
KORUPENSAMINE-B IC50=0.2-0.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
KORUPENSAMINE-E IC50=2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
LICOCHALCONE-A *
LIMACINE IC50=0.05-0.79 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
LYCORINE IC50=0.3-0.7 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
MAACKIAIN EC50=10 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
MACRALSTONINE IC50=8.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
MACROCARPAMINE IC50=0.4-32.6 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
MELDENIN IC50=5.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
METHYLANGOLENSATE IC50=5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Punica granatum Pomegranate; Grenadier (Fr.); Granatapfelbaum (Ger.); Granatapfelstrauch (Ger.); Zakuro (Jap.); Romanzeiro (Port.); Granado (Sp.); Mangrano (Sp.) 6 134, 400
Putoria calabrica 1 0
Pygeum acuminatum 1 0
Pyrus communis Pear 2 28
Quercus alba White Oak 1 0
Quercus bambusaefolia 1 3.700000047683716
Quercus championi 1 3.299999952316284
Quercus infectoria Aleppo Oak; Dyer's Oak; Gall Oak 2 0
Quercus myrsinaefolia 1 1.100000023841858
Quercus robur English Oak 1 0
Quercus rubra Northern Red Oak 1 0
Quercus suber Cork Oak 1 0
Quercus velutina Black Oak 1 0
Quisqualis indica Rangoon Creeper 1 0
Rauvolfia serpentina Indian Snakeroot; Serpentine Wood 1 0
Rauvolfia tetraphylla Four-Leaf Devilpepper; Pinque-Pinque 1 0
Rauvolfia vomitoria African Snakeroot 1 0
Rhododendron arboreum 1 0
Rhododendron dauricum Chinese Alpenrose 2 0
Rhododendron falconeri 1 0