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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antiplasmodial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
OLEANOLIC-ACID IC50=70-89 ug/ml *
OPHIOBOLIN-A IC50=0.5-0.6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OSUPUPINE IC50= 0.25ug/ml *
OXYACANTHINE IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PALMITINE-CHLORIDE IC50= 0.36ug/ml *
PATCHOULENE IC50=108 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHEANTHINE IC50=1,400 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PIPERINE Sabinsa: A series of well documented proprietary PR booklets,
e.g.Sabinsa Corps. 1998. Bronchial Asthma - Its etiology and control with traditional herbal extracts. Sabinsa Corporation. Piscataway, NJ. 49 pp.
PIQUEROL-A IC50=100 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLEIOCARPAMINE IC50=6-20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN IC50=0.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN IC50=0.178-0.189 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PRISTIMERIN IC50=0.19-28 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PSYCHOTRINE IC50=0.1-0.4 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PUNICALAGIN 1.5-8 ug/ml *
PUNICALAGIN IC50=7.5-8.8 uM *
QUERCETIN IC50=13-64 *
QUINDOLINE IC50=>229 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ROEMREFRIDINE IC50=0.6-0.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
RUBIADIN-1-METHYL-ETHER IC50=8-83 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Platanus acerifolia 1 18, 000
Platanus occidentalis 1 17, 500
Platanus orientalis 1 17, 500
Platanus vulgaris 1 0
Plectranthus amboinicus Amboini Coleus; Country Borage; Cuban Oregano; French Thyme; Indian Borage; Soup Mint; Spanish Thyme; Mexican Mint 2 0
Plectranthus urticifolius 1 0
Plumeria acutifolia Frangipani 1 0
Plumeria obtusa 1 3.4000000953674316
Podophyllum hexandrum Himalayan Mayapple 2 12, 000
Podophyllum peltatum Mayapple 2 50, 000
Podophyllum pleianthum Chinese Mayapple 1 0
Pogostemon cablin Patchouli 1 0
Polianthes tuberosa Tuberose 1 0
Polygonum aviculare Prostrate Knotweed 1 0
Polygonum hydropiper Common Smartweed 2 0
Polygonum hydropiperoides Mild Water Pepper 1 0
Polygonum multiflorum Chinese Cornbind; Fleeceflower; Fo Ti; He Shou Wu; Chinese Knotweed 1 0
Polygonum plebeium 1 75
Pongamia pinnata 1 45
Populus balsamifera Balsam Poplar 1 0