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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antiplasmodial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(-)-CURINE IC50=353 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CYCLEAPELTINE IC50=0.03-0.04 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-DICENTRINE IC50=1260-2550 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ISOLAURELINE IC50=1610-2560 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-NOR-DICENTRINE IC50=470-1030 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ROEMEROLINE IC50=1,780-3,150 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-TETRAHYDROSTEPHABINE IC50=1,940-2,230 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-THAICANINE IC50=550-1,610 u/gml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-XYLOPINE IC50=440-2,270 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1,2-DI-O-ACETYLCORINE IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-BETA-HYDROPEROXYISOBILIN IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-DEACETYLKHIVORIN IC50=10 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-HYDROXYBENZOISOCHROMAN IC50=2.7 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-O-ACETYLNORPLUVIININE IC50=28.3-34.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
10'-HYDROXYUSAMBARENSINE IC50=0.2-0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
10,12-PEROXYCALAMENENE IC50=2.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
11-METHOXYAKUAMMICINE IC50=41.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
12-METHOXY-NB-METHYLVOACHOLATINE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
13-BETA-D-DIHYDROEURYCOMANOL IC50=0.5-2.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
14-HYDROXYCHAPARRINONE IC50=0.188 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Diospyros zenkeri 1 706.7000122070312
Dipterocarpus glandulosus 1 0
Dipterocarpus hispidus 1 140
Dipterocarpus insignis 1 0
Dipterocarpus zeylanicus 1 0
Discaria longispina 1 0
Dodonaea viscosa Hopwood 1 0
Drimys winteri Winter's Bark 1 0
Duboisia myoporoides Corkwood Tree; Pituri 1 20
Duchesnea indica False Strawberry; Indian Strawberry; Mock Strawberry 2 943.8000000715256
Echinacea angustifolia Echinacea; Narrow Leaf Echinacea; Narrow Leaf Purple-Coneflower 1 0
Echinacea purpurea Echinacea; Eastern Purple-Coneflower; Purple-Coneflower 1 0
Echinacea spp Coneflower; Echinacea 2 24
Echinops echinatus 1 0
Echinops niveus 1 0
Ehretia laevis 1 150
Elaeagnus angustifolia Russian Olive; Silver Berry 3 4, 280
Elaeagnus pungens Thorny Silver Berry 2 0
Elettaria cardamomum Cardamom 2 0
Eleutherococcus senticosus Eleuthero Ginseng; Siberian Ginseng; Spiny Ginseng; Wu jia; Ci wu jia (Pinyin) 2 420