Biological Activity Antimalarial | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
BRUCEINE-A	IC50=0.021-0.5 uM	Duke, 1992 *
BRUCEINE-A	IC50=0.005-0.011 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-B	IC50=11 ng/ml	Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-B	IC50=0.023-0.5 uM	Duke, 1992 *
BRUCEINE-B	IC50=0.005-0.011 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C	IC50=0.5 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C	IC50=5 ng/ml	Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-C	IC50=0.009 uM	Duke, 1992 *
BRUCEINE-C	IC50=0.005-0.011 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-D	IC50=0.037-0.5 uM	Duke, 1992 *
BRUSATOL	IC50=0.006 uM	Duke, 1992 *
CARYOPHYLLENE-16-ALPHA-OXIDE	IC50=345 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CARYOPHYLLENE-ALPHA-OXIDE	EC50=>3-100 uM	Duke, 1992 *
CASTICIN	IC50=24 uM	Duke, 1992 *
CASTICIN	(Synergic w artemisinin)	Duke, 1992 *
CEDRELONE	IC50=0.77 ug/ml	Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
CEDRONIN	IC50=0.23-0.25 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CELASTROL	IC50=0.181-0.254 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CEPHAELINE	IC50=0.011-0.027 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CHAPARRINONE	IC50=0.037 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Rosa damascena	Damask Rose	1	0
Rosa davurica	not available	1	70
Rosa multiflora	Multiflora Rose	1	0
Rosa spp	Rose Hips	1	0
Rosa woodsii	Woods' Rose	2	68
Rosmarinus officinalis	Rosemary	7	243, 686.40000009537
Rotala floribunda	not available	1	0
Rubus fruticosus	Blackberry	2	0
Rubus idaeus	Red Raspberry; Raspberry	3	100
Rumex acetosa	Garden Sorrel	2	12, 800
Rumex acetosella	Sheep Sorrel	1	5, 300
Rumex crispus	Curly Dock; Lengua De Vaca; Yellow Dock; Sour Dock	2	0
Ruscus aculeatus	Butcher's Broom; Box-Holly	1	1, 600
Ruta graveolens	Rue	4	20, 000
Salix alba	White Willow	2	0
Salvia dorisiana	'Honduran' Sage	2	4.5000001192092896
Salvia farinacea	not available	1	0
Salvia longistyla	not available	1	28.200000762939453
Salvia mexicana	not available	1	0
Salvia nicolsoniana	not available	1	58.70000076293945