Biological Activity Antimalarial | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
BRUCEINE-A	IC50=0.005-0.011 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-A	IC50=11 ng/ml	Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-B	IC50=0.023-0.5 uM	Duke, 1992 *
BRUCEINE-B	IC50=0.005-0.011 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-B	IC50=11 ng/ml	Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-C	IC50=5 ng/ml	Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-C	IC50=0.009 uM	Duke, 1992 *
BRUCEINE-C	IC50=0.005-0.011 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C	IC50=0.5 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-D	IC50=0.037-0.5 uM	Duke, 1992 *
BRUSATOL	IC50=0.006 uM	Duke, 1992 *
CARYOPHYLLENE-16-ALPHA-OXIDE	IC50=345 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CARYOPHYLLENE-ALPHA-OXIDE	EC50=>3-100 uM	Duke, 1992 *
CASTICIN	IC50=24 uM	Duke, 1992 *
CASTICIN	(Synergic w artemisinin)	Duke, 1992 *
CEDRELONE	IC50=0.77 ug/ml	Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
CEDRONIN	IC50=0.23-0.25 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CELASTROL	IC50=0.181-0.254 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CEPHAELINE	IC50=0.011-0.027 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CHAPARRINONE	IC50=0.037 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Schinus molle	California Peppertree; Mastic-Tree; Peruvian Peppertree	1	0
Schinus terebinthifolius	Brazilian Peppertree	1	0
Schleichera oleosa	not available	1	0
Schrebera swietenioides	not available	1	0
Scirpus fluviatilis	not available	1	27
Scirpus tuberosus	not available	1	0
Scoparia dulcis	not available	1	500
Scopolia carniolica	Scopolia	1	0
Scutellaria lateriflora	Mad-Dog Skullcap; Scullcap	1	0
Selenicereus grandiflorus	Night-Blooming Cereus; Queen-of-the-Night	1	0
Senna lindheimeriana	not available	1	50.400001525878906
Senna occidentalis	Coffee Senna	1	0
Serenoa repens	Saw Palmetto; Scrub-Palmetto	2	0
Shorea affinis	not available	1	720
Shorea congestiflora	not available	1	0
Shorea dyerii	not available	1	430
Shorea magistophylla	not available	1	20
Shorea oblongifolia	not available	1	0
Shorea ovalifolia	not available	1	0
Shorea stipularvis	not available	1	710