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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
3-METHYLNAPHTHARAZIN IC50=5.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-O-BENZOYLHOSLOPPONE IC50=0.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
4,7-DIMETHYL-1-TETRALONE EC50=>3-100 uM *
5,6,7-TRIMETHOXYCOUMARIN IC50=1ug/ml *
5,7-DIMETHOXY-8-(3'-HYDROXY-3'-METHYL-1'-BUTENE) IC50=8.8-16.25 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6'-DESMETHYL-THALIFABORAMINE IC50=0.01-0.15 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6-ACETYLSWIETENOLIDE IC50=7.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6-ALPHA-TIGLOYLOXYGLAUCARUBOL IC50=0.257 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-DEACETYLGEDUNIN IC50=3.6 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
7-DEACETYLKHIVORIN IC50=5 ug/ml *
7-EPIDIONCHOPHYLLINE-A IC50=0.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-METHOXY-BETA-CARBOLINE-1-PROPIONIC-ACID IC50=0.3-2.9 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-O-DEMETHYLTETRANDRINE IC50=0.74 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
8-EPIXANTHIN IC50=125 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
8-EPIXANTHIN-1,5-EPOXIDE IC50=7.8 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ACACETIN IC50=4.2-12.6 ug/ml *
AFFINISINE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
AILANTHINONE IC50=0.025 uM *
AILANTHONE Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
AJOENE 50 mg/kg *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Caulophyllum thalictroides Blue Cohosh 1 0
Ceanothus americanus 1 7, 479
Ceanothus velutinus 1 0
Cedrus deodora Deodar Cedar 1 0
Ceiba pentandra Kapok; Silk-Cotton Tree 3 0
Centaurea calcitrapa Star-Thistle 2 0
Centaurea cyanus Cornflower; Bachelor's Button 1 0
Centaurium erythraea Centaury 2 0
Centella asiatica Gotu Kola; Pennywort 2 2, 200
Cephaelis ipecacuanha Ipecac; Raicilla 3 96, 900
Cephalotaxus drupacea Plum Yew 1 0
Cephalotaxus fortunei Fortune's Plum Yew 1 0
Cephalotaxus harringtonii Japanese Plum Yew 1 1.2000000476837158
Cephalotaxus spp Generic Plum Yew 1 0
Ceratonia siliqua Carob; St.John's-Bread; Locust Bean 1 0
Chamaecrista greggii 1 14.800000190734863
Chamaemelum nobile Garden Camomile; Perennial Camomile; Roman Camomile 5 0
Chelidonium majus Celandine 1 0
Chenopodium album Lambsquarter 2 0
Chenopodium ambrosioides Epazote; Wormseed 1 36, 000