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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Biological Activity Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(+)-1,2-DEHYDROTELOBINE IC50=0.26-0.31 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-N-METHYLTELOBINE IC50=0.09-0.26 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-CEPHARANTHINE IC50=0.05-0.13 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-ISOTETRANDRINE IC50=0.05-0.07 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-OBABERINE IC50=0.05-0.09 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-THALRUGOSINE IC50=0.07-0.13 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-AROMOLINE IC50=0.67 ug/ml (ca 1/5 chloroquine) *
(+)-CEPHARANTHINE IC50=0.14-0.30 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-CRINAMINE IC50=2.8-3.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-DEPHNANDRINE IC50=0.06-0.22 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-HOMOAROMOLINE IC50=0.02-0.29 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-ISOTETRANDRINE IC50=0.05-0.17 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-OBABERINE IC50=0.22-0.23 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-STEPHIBABERINE IC50=0.13-0.31 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-TETRANDRINE IC50=0.16-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-THALRUGOSINE IC50=0.06-0.23 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ANONAINE IC50=1290-1900 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ASIMILOBINE IC50=470-950 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CAPAURINE IC50=1910-4340 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CASSYTHICINE IC50=2260-2290 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Caulophyllum thalictroides Blue Cohosh 1 0
Ceanothus americanus 1 7, 479
Ceanothus velutinus 1 0
Cedrus deodora Deodar Cedar 1 0
Ceiba pentandra Kapok; Silk-Cotton Tree 3 0
Centaurea calcitrapa Star-Thistle 2 0
Centaurea cyanus Cornflower; Bachelor's Button 1 0
Centaurium erythraea Centaury 2 0
Centella asiatica Gotu Kola; Pennywort 2 2, 200
Cephaelis ipecacuanha Ipecac; Raicilla 3 96, 900
Cephalotaxus drupacea Plum Yew 1 0
Cephalotaxus fortunei Fortune's Plum Yew 1 0
Cephalotaxus harringtonii Japanese Plum Yew 1 1.2000000476837158
Cephalotaxus spp Generic Plum Yew 1 0
Ceratonia siliqua Carob; St.John's-Bread; Locust Bean 1 0
Chamaecrista greggii 1 14.800000190734863
Chamaemelum nobile Garden Camomile; Perennial Camomile; Roman Camomile 5 0
Chelidonium majus Celandine 1 0
Chenopodium album Lambsquarter 2 0
Chenopodium ambrosioides Epazote; Wormseed 1 36, 000