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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Biological Activity Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
11-BETA-ACETOXYKHIVORIN IC50=50 ug/ml *
11-METHOXYAKUAMMICINE IC50=41.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
12-METHOXY-NB-METHYLVOACHOLATINE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
13-BETA-D-DIHYDROEURYCOMANOL IC50=0.5-2.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
14-HYDROXYCHAPARRINONE IC50=0.188 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
15-DESACETYLUNDULATONE IC50=0.047 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
16-EPIAFFININE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
17-METHOXY-28-NORISOIGUESTERIN IC50=0.028-0.37 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
18-HYDROXYISOSUNGUCINE IC50=0.1-0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
18-HYDROXYSUNGUCINE IC50=1-4 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
2-(2,4-DIHYDROXYPHENYL)-5,6-METHYLENEDIOXYBENZOFURAN EC50=27 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
20-EPIANTIRHINE IC50=7.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
28-NOR-IGOIGUESTERIN-17-CARBALDEHYDE IC50=0.080-0.094 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3',4'-DIHYDROUSAMBARENSINE IC50=0.01 ug/ml *
3,4,5-TRIMETHOXYPHENYL(6'-O-GALLOYL)-O->D-GLUCOPYRANOSIDE IC50=3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-DEACETYLKHIVORIN IC50=50 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
3-DESACETYLYKHIVORIN IC50=50 ug/mL) *
3-HYDROXY-6'-DESMETHYL-9-O-METHYL-THALIFABORAMINE IC50=0.05-0.24 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-HYDROXY-THALIFABORAMINE IC50=0.01-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-METHOXYSAMPANGINE IC50=0.09-0.28 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Ocimum canum Hoary Basil 3 0
Ocimum gratissimum Agbo; Shrubby Basil 2 1, 140
Ocimum suave Kenyan Tree Basil 1 0
Ocimum tenuiflorum Anise-Scented Basil 3 7, 090
Oenanthe aquatica Water Fennel; Water Hemlock 1 0
Oenanthe crocata Water Dropwort 1 0
Oenothera biennis Evening-Primrose 3 207, 000
Olea europaea Olive 5 0
Ononis spinosa Spiny Restharrow; Restharrow; Hauhechel (Ger.) 1 0
Opopanax chironium Hercules All Heal; Opopanax 1 0
Opuntia ficus-indica Indian Fig; Prickly Pear; Nopal; Nopalito 1 0
Origanum compactum 1 70
Origanum majorana Marjoram; Sweet Marjoram 4 13, 600
Origanum onites Oregano; Pot Marjoram 1 40
Origanum vulgare Common Turkish Oregano; Wild Oregano; Oregano; Pot Marjoram; Wild Marjoram; European Oregano 4 18, 600
Paeonia japonica 1 5, 000
Paeonia lactiflora Chih-Shao; Peony; Common Garden Peony; White Peony; Bai Shao (Chinese) 1 0
Paeonia moutan Moutan; Tree Peony 1 0
Paeonia suffruticosa Moutan; Tree Peony; Moutan Peony 1 0
Palaquium grande 1 7