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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
QUERCETIN IC50=1-6.4 ug/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
QUINDOLINE IC50=>229 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
QUINICINE IC50=11.2 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUINIDINE 10 mg/kg/orl/man/8 hrs Martindale's 29th
QUINIDINONE IC50=4.7 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUININE IC50=0.18 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUININE-SULFATE 2,000 mg/man/day Martindale's 28th
QUINOLINE Merck 11th Edition
ROBUSTANOL *
ROEMREFRIDINE IC50=0.6-0.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
RUBIADIN-1-METHYL-ETHER IC50=8-83 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
RUGOSAL-A IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
RUTIN IC50=>100 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
SALANNIN IC50=50 ug/ml *
SAMADERINE-B-CHAPARRINONE IC50=0.071 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SAMADERINE-E-CHAPARRINONE IC50=0.021 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SAMADERINE-X-CHAPARRINONE IC50=0.015 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SAMADERINE-Z-CHAPARRINONE IC50=0.071 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SARACHINE IC50=0.01-0.07 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SECURINE IC50=5.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Echinacea spp Coneflower; Echinacea 3 24
Echinops echinatus 1 0
Echinops niveus 1 0
Ehretia laevis 1 150
Elaeagnus angustifolia Russian Olive; Silver Berry 4 4, 280
Elaeagnus pungens Thorny Silver Berry 3 0
Elettaria cardamomum Cardamom 3 0
Eleutherococcus senticosus Eleuthero Ginseng; Siberian Ginseng; Spiny Ginseng; Wu jia; Ci wu jia (Pinyin) 3 728.0000019073486
Elsholtzia cristata Furan Chemotype 1 55
Elsholtzia pilosa Hairy Mint Shrub 2 16
Elsholtzia polystachya Bush Mint 3 59.20000019669533
Enterolobium cyclocarpum 1 60
Ephedra gerardiana Pakistani Ephedra 1 0
Ephedra sinica Ma Huang; Chinese Ephedra 1 0
Epilobium rosmarinifolium 1 0
Equisetum arvense Field Horsetail; Horsetail 1 0
Eriobotrya japonica Loquat 4 11, 455.599975585938
Erythrospermum zeylanicum 1 110
Erythroxylum coca Coca 1 5, 000
Erythroxylum novogranatense Coca 1 5, 000