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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
OPHIOBOLIN-A IC50=0.5-0.6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OSTHOL IC50=25.1 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
OSTHOLE *
OSTRUTHIN *
OXYACANTHINE IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PALMATINE *
PATCHOULENE IC50=108 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHAEANTHINE IC50=1.43 ug/ml (1/10 x chloroquine) *
PHEANTHINE IC50=1,400 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHLORIDZIN *
PHLORIZIN *
PIQUEROL-A IC50=100 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLEIOCARPAMINE IC50=6-20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN IC50=0.178-0.189 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN IC50=0.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PRIEURIANIN IC50=14.08 ug/mL) *
PRISTIMERIN IC50=0.19-28 ug/ml *
PSYCHOTRINE IC50=0.1-0.4 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PUNICALAGIN 2-8 ug/ml *
PYCNAMINE IC50=0.15 ug/mL (ca 1 x chloroquine) *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Diospyros discolour 1 1, 300
Diospyros ebenum 1 80
Diospyros eriantha 1 0
Diospyros ferrea 1 0
Diospyros fragrans 1 0
Diospyros gabunensis 1 0
Diospyros gracilescens 1 60
Diospyros greenwayi 1 60
Diospyros hirsuta 1 700
Diospyros hoyleana 1 410
Diospyros ismailii 1 0
Diospyros iturensis 1 660
Diospyros japonica 1 0
Diospyros kaki Persimmon 1 0
Diospyros kamerunensis 1 0
Diospyros leucomelas 1 0
Diospyros longiflora 1 393
Diospyros lotus 1 20
Diospyros mafiensis 1 200
Diospyros maingayi 1 0