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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
HEXAMETHOXYLIGNAN IC50=37-50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HOMOHARRINGTONINE Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
HUMULENE IC50=86 ug/ml *
HYDRANTHINE-A IC50=0.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HYDROQUINIDINE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
HYDROQUINONE *
HYDROXYCRYPTOLEPINE IC50=77-102 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ICAJINE IC50=>80-95 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOCHONDRODENDRINE IC50=892 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOCRYPTOLEPINE IC50=0.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOFEBRIFUGINE IC50=0.002-0.003 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOFRAXIDIN IC50=7.95 ug/ml *
ISOIGUESTEROL IC50=0.023-0.54 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOMELDENIN IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOSTRYCHNINE IC50=14->20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOSUNGUCINE IC50=0.3-1.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOTETRANDRINE IC50=0.07 ug/ml (2 x chloroquine) *
ISOTETRANDRINE IC50=100 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
JATRORRHIZINE IC50=0.42-1.61 ug/ml *
KHAYANTHONE IC50=50 ug/mL) *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Caulophyllum thalictroides Blue Cohosh 1 0
Ceanothus americanus 1 7, 479
Ceanothus velutinus 1 0
Cedrus deodora Deodar Cedar 1 0
Ceiba pentandra Kapok; Silk-Cotton Tree 3 0
Centaurea calcitrapa Star-Thistle 2 0
Centaurea cyanus Cornflower; Bachelor's Button 1 0
Centaurium erythraea Centaury 2 0
Centella asiatica Gotu Kola; Pennywort 2 2, 200
Cephaelis ipecacuanha Ipecac; Raicilla 3 96, 900
Cephalotaxus drupacea Plum Yew 1 0
Cephalotaxus fortunei Fortune's Plum Yew 1 0
Cephalotaxus harringtonii Japanese Plum Yew 1 1.2000000476837158
Cephalotaxus spp Generic Plum Yew 1 0
Ceratonia siliqua Carob; St.John's-Bread; Locust Bean 1 0
Chamaecrista greggii 1 14.800000190734863
Chamaemelum nobile Garden Camomile; Perennial Camomile; Roman Camomile 5 0
Chelidonium majus Celandine 1 0
Chenopodium album Lambsquarter 2 0
Chenopodium ambrosioides Epazote; Wormseed 1 36, 000