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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
HEXAMETHOXYLIGNAN IC50=37-50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HOMOHARRINGTONINE Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
HUMULENE IC50=86 ug/ml *
HYDRANTHINE-A IC50=0.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HYDROQUINIDINE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
HYDROQUINONE *
HYDROXYCRYPTOLEPINE IC50=77-102 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ICAJINE IC50=>80-95 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOCHONDRODENDRINE IC50=892 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOCRYPTOLEPINE IC50=0.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOFEBRIFUGINE IC50=0.002-0.003 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOFRAXIDIN IC50=7.95 ug/ml *
ISOIGUESTEROL IC50=0.023-0.54 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOMELDENIN IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOSTRYCHNINE IC50=14->20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOSUNGUCINE IC50=0.3-1.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOTETRANDRINE IC50=0.07 ug/ml (2 x chloroquine) *
ISOTETRANDRINE IC50=100 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
JATRORRHIZINE IC50=0.42-1.61 ug/ml *
KHAYANTHONE IC50=50 ug/mL) *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Phaseolus aborigineus 1 0
Phaseolus vulgaris Black Bean; Green Bean; Haricot Bean; Garden Bean; String Bean; Dwarf Bean; Field Bean; Flageolet Bean; French Bean; Kidney Bean; Navy Bean; Pop Bean; Popping Bean; Snap Bean; Wax Bean; Haricot Vert; Haricot 1 0
Phellodendron amurense Huang Po; Po Mu; Amur Cork Tree; Huang Bai 4 80, 000
Phoenix dactylifera Date Palm 3 0
Phoradendron juniperinum 1 3
Phyllanthus amarus 2 1, 588
Phyllanthus discoideus 1 0
Phyllanthus emblica Emblic; Myrobalan 4 119, 900
Phyllanthus niruri Seed On The Leaf 3 0
Phyllanthus reticulatus 1 3.299999952316284
Physalis peruviana Cape Gooseberry; Ground Cherry 1 0
Phytolacca americana Pokeweed 1 0
Picramnia sellowii 1 0
Pilocarpus microphyllus Maranhao Jaborandi 1 100
Pimenta dioica Allspice; Jamaica-Pepper; Pimenta; Clover-Pepper; Pimento 2 1, 800
Pimpinella anisum Anise; Sweet Cumin 3 0
Pinus mugo Dwarf Pine; Swiss Mountain Pine 1 0
Pinus sylvestris Scotch Pine 3 0
Piper auritum Cordoncillo; Hierba Santa; Hoja Santa 1 0
Piper cubeba Cubeb; Cubeb Pepper 2 85, 200