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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
DIUVERETIN EC50=4.2 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
ECHITAMINE 1.6 mg/kg *
ELLAGIC-ACID IC50=0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EMETINE Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
ENTANDROPHRAGMIN IC50=50 *
EPOXYADADIRADONE IC50=0.77 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
ETHYL-CRYPTOLEPIDONOATE IC50=3.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EUPATORIN IC50=65 uM *
EURYCOMALACTONE *
EURYCOMANOL IC50=1.2-4.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EURYCOMANOL-2-O-BETA-D-GLUCOPYRANOSIDE IC50=0.4-3.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EURYCOMANONE IC50=1.2-4.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EVODULONE IC50=18.27 ug/mL) *
EVOXANTHINE IC50=67.6 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
EXIGUAFLAVANONE-A IC50=4.6-7.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EXIGUAFLAVONE-A EC50=4.6 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
EXIGUAFLAVONE-B EC50=7 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
FAGARAMIDE IC50=12.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
FAGARONINE IC50=0.009 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
FEBRIFUGINE IC50=0.001-0.07 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Schinus molle California Peppertree; Mastic-Tree; Peruvian Peppertree 1 0
Schinus terebinthifolius Brazilian Peppertree 1 0
Schleichera oleosa 1 0
Schrebera swietenioides 1 0
Scirpus fluviatilis 1 27
Scirpus tuberosus 1 0
Scoparia dulcis 1 500
Scopolia carniolica Scopolia 1 0
Scutellaria lateriflora Mad-Dog Skullcap; Scullcap 1 0
Selenicereus grandiflorus Night-Blooming Cereus; Queen-of-the-Night 1 0
Senna lindheimeriana 1 50.400001525878906
Senna occidentalis Coffee Senna 1 0
Serenoa repens Saw Palmetto; Scrub-Palmetto 2 0
Shorea affinis 1 720
Shorea congestiflora 1 0
Shorea dyerii 1 430
Shorea magistophylla 1 20
Shorea oblongifolia 1 0
Shorea ovalifolia 1 0
Shorea stipularvis 1 710