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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
DIUVERETIN EC50=4.2 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
ECHITAMINE 1.6 mg/kg *
ELLAGIC-ACID IC50=0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EMETINE Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
ENTANDROPHRAGMIN IC50=50 *
EPOXYADADIRADONE IC50=0.77 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
ETHYL-CRYPTOLEPIDONOATE IC50=3.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EUPATORIN IC50=65 uM *
EURYCOMALACTONE *
EURYCOMANOL IC50=1.2-4.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EURYCOMANOL-2-O-BETA-D-GLUCOPYRANOSIDE IC50=0.4-3.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EURYCOMANONE IC50=1.2-4.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EVODULONE IC50=18.27 ug/mL) *
EVOXANTHINE IC50=67.6 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
EXIGUAFLAVANONE-A IC50=4.6-7.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EXIGUAFLAVONE-A EC50=4.6 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
EXIGUAFLAVONE-B EC50=7 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
FAGARAMIDE IC50=12.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
FAGARONINE IC50=0.009 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
FEBRIFUGINE IC50=0.001-0.07 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Terminalia bellirica Beleric Myrobalan; Bahera; Myrobalan Belleric; Myrobalan; Belleric 2 0
Terminalia catappa Indian Almond; Tropical Almond; Malabar Almond 5 14, 437.5
Terminalia chebula Ink Nut; Myrobalan; Black Myrobalan; Chebulic Myrobalan 4 210, 516
Terminalia ivorensis Idigbo; Emire; Blackbark; Black Afara; Brimstonewood; Satinwood; Shinglewood 2 0
Terminalia pallida 2 0
Ternstroemia gymnanthera 2 0
Ternstromia merriliana 1 20, 000
Tetracera akara 1 10, 500
Tetracera indica 1 6, 000
Tetracera sarmentosa 1 12, 300
Tetracera scandens 1 13, 500
Teucrium arduini 'Croatian Alpine' Germander 1 116
Teucrium botrys Field Germander 1 0
Teucrium chamaedrys Wall Germander 1 0
Teucrium cyprium 'Cyprus' Germander 3 465
Teucrium divaricatum Hoary Divaricate Germander 3 42
Teucrium gnaphalodes Iberian Germander 2 67
Teucrium kotschyanum Stavros Kotschy's Germander 3 300
Teucrium micropodioides Small 'Cyprus' Germander 3 188
Teucrium montanum Mountain Germander 1 0