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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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  2. (+)-TETRANDRINE

(+)-TETRANDRINE

Chemical ID
+TETRANDRINE
Ubiquitous
No
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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
ACE-Inhibitor 1 mM/ *
Antimalarial IC50=0.16-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antiplasmodial IC50=0.16-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Calcium-Antagonist 13-100 uM mus, rat *
Calcium-Antagonist ED50=20 uM *
Calcium-Antagonist 100 mg/kg *
Calcium-Antagonist 1-100 uM gpg *
Calcium-Antagonist IC50=0.27-25 uM *
Calcium-Antagonist 50 uM hmn, cow *
Calcium-Antagonist 30 uM frg (=verapamil) *
Calcium-Antagonist IC50=0.1-10.1 uM pig, rat *
Prostaglandin-Synthesis-Inhibitor 10 uM Pang, L. H., Hoult, J. R. S. 1997. Cytotoxicity to Macrophages of Tetrandrine, an Antisilicosis Alkaloid, Accompanied by an Overproduction of Prostaglandins. Biochem Pharmacol, 53(6): 773-782.