| EMBININ |
IC13=10 uM |
Shimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888. |
| EMODIN |
IC50=15.9 uM |
Duke, 1992 * |
| ETHYL-BREVIFOLIN-CARBOXYLATE |
IC50=5 uM |
Shimizu, M., Horie, S., Terashima, S., Ueno, H., et al. 1989. Studies on Aldose Reductase Inhibitors from Natural Products.II. Active Components of a Paraguayan Crude Drug 'Para-parai mi,' Phyllanthus niruri. Chem. Pharm. Bull. 37(9): 2531-2532, 1989. |
| EUGENOL-BETA-D-GLUCOSIDE |
0.1 mM/l rat (weak activity, 35.2% inhibition) |
Fujita, T., Ohira, K., Miyatake, K., Nakano, Y., Nakayama, M. 1995. Inhibitory Effect of Perillosides A and C, Related Monoterpene Glucosides on Aldose Reductase and Their Structure-Activity Relationships. Chem Pharm Bull, 43(6): 920-926. |
| EUPATILIN |
IC50=25 uM rat (weak activity) |
Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345. |
| FLAVOCANNABISIDE |
not available |
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. |
| FLAVOSATIVASIDE |
not available |
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. |
| FORSYTHOSIDE-B |
IC50=4.83 uM |
Andary, C. Caffeic Acid Glycoside Esters and Pharmacology. Polyphenolic Phenom, 1993: 237-245. |
| FRAXIN |
10 ug/ml cow |
Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 |
| FRAXINOL |
10 ug/ml cow |
Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 |
| GAMMA-TERPINENE |
100 ug/ml |
Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. |
| GENISTEIN |
IC50=10 uM |
Duke, 1992 * |
| GOSSYPETIN-8-GLUCOSIDE |
not available |
Duke, 1992 * |
| GOSSYPOL |
not available |
Deck, L. M., Vander Jagt, D. L., Royer, R. E. 1991. Gossypol and Derivatives: A New Class of Aldose Reductase Inhibitors. J Med Chem, 34(1): 3301-3305. |
| GUAIJAVERIN |
IC50=0.18 uM |
Yoshikawa, M., et al. 1998. Antidiabetic Principles of Natural Medicines. II. Aldose Reductase and Alpha-Glucosidase Inhibitors from Brazilian Natural Medicine, the Leaves of Myrcia multiflora DC. (....). Chem Pharm Bull, 46(1): 113-119. |
| HAEMATOXYLIN |
not available |
Duke, 1992 * |
| HERNIARIN |
10 ug/ml cow (weak activity) |
Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 |
| HISPIDULOSIDE |
ED50=1-10 uM |
Duke, 1992 * |
| HYMENOXIN |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| HYPERIN |
not available |
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
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