| 3,3',4-TRI-O-METHYL-ELLAGIC-ACID |
IC50=0.08 uM |
Terashima, S., Shimizu, M., Nakayama, H., Ishikura, M., et al. 1990. Studies on Aldose Reductase Inhibitors from Medicinal Plant of 'Sinfito,' Potentilla candicans, and Further Synthesis of Their Related Compounds. Chem. Pharm. Bull 38(10):2733-2736, 1990 |
| 3,4-DIMETHOXYCINNAMIC-ACID |
4 ug/ml (weak activity) |
Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110. |
| 3-(PENTADECA-CIS-8-CIS-11,14-TRIENYL)-PHENOL |
IC50=180.9 uM |
Toyomizu, M., Sugiyama, S., Jin, R. L., Nakatsu, T. 1993. Alpha-Glucosidase and Aldose Reductase Inhibitors: Constituents of Cashew, Anacardium occidentale, Nut Shell Liquids. Phytotherapy Research, 7(3): 252-254. |
| 3-(PENTADECA-CIS-8-CIS-12-DIENYL)-PHENOL |
IC50=332.8 uM |
Toyomizu, M., Sugiyama, S., Jin, R. L., Nakatsu, T. 1993. Alpha-Glucosidase and Aldose Reductase Inhibitors: Constituents of Cashew, Anacardium occidentale, Nut Shell Liquids. Phytotherapy Research, 7(3): 252-254. |
| 3-ACETYL-3',4'-DIHYDROXY-5,6,7-TRIMETHOXY-FLAVONE |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 3-HYDROXY-6-METHOXY-COUMARIN |
10 uM (weak activity) |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 3-HYDROXY-COUMARIN |
10 uM (weak activity) |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 4',5,6,7-TETRAHYDROXY-3',8-DIMETHOXY-FLAVONE |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 4',5,7-TRIHYDROXY-6,8-DIMETHOXY-FLAVONE |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 4',6-DIHYDROXY-3',5,7,8-TETRAMETHOXY-FLAVONE |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 4',6-DIHYDROXY-5,7,8-TRIMETHOXY-FLAVONE |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 4'-HYDROXY-3',5,6,7,8-PENTAMETHOXY-FLAVONE |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 4'-HYDROXY-5,6,7,8-TETRAMETHOXY-FLAVONE |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 4-(ALPHA-RHAMNOPYRANOSYL)ELLAGIC-ACID |
IC50=4.1 x 10(-8) M |
Duke, 1992 * |
| 4-HYDROXY-6,7-METHYLENEDIOXY-COUMARIN |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 4-HYDROXYCOUMARIN |
IC50=0.53 ug/ml cow |
Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 |
| 4-METHOXYCOUMARIN |
10 ug/ml cow |
Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 |
| 4-O-METHYLELLAGIC-ACID |
not available |
Duke, 1992 * |
| 5,6,7-TRIHYDROXY-8-METHOXY-FLAVONE |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 5,6-DIHYDROXY-7,8-DIMETHOXY-FLAVONE |
10 uM |
Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
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