3
|
3,3',4-TRI-O-METHYL-ELLAGIC-ACID
|
Root |
-- |
-- |
-- |
* |
Aldose-Reductase-Inhibitor IC50=0.08 uM
Terashima, S., Shimizu, M., Nakayama, H., Ishikura, M., et al. 1990. Studies on Aldose Reductase Inhibitors from Medicinal Plant of 'Sinfito,' Potentilla candicans, and Further Synthesis of Their Related Compounds. Chem. Pharm. Bull 38(10):2733-2736, 1990
Antihemorrhagic
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Cytotoxic ED50(KB)=7.7 ug/ml
*
|
0
|
DELPHINIDIN-3-ARABINOSIDE
|
Plant |
-- |
-- |
-- |
* |
0
|
DIHYDROVERTICILLATINE
|
Plant |
-- |
-- |
-- |
* |
51
|
ELLAGIC-ACID
|
Leaf |
-- |
-- |
-- |
* |
Abortifacient 1.2 mg/kg ivn mus
*
ACE-Inhibitor IC50=5 mM/l
*
Aldose-Reductase-Inhibitor IC50=0.2 ug/ml (strong activity)
*
Aldose-Reductase-Inhibitor IC50=0.2 uM
*
Antibacterial ID50=20 ug/ml
*
Antibacterial 1,250 ug/ml
*
Anticancer (Cervix)
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Colon)
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Esophagus)
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Mouth)
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticariogenic ID50=20 ug/ml
*
Anticataract
Shimizu, M., Horie, S., Terashima, S., Ueno, H., et al. 1989. Studies on Aldose Reductase Inhibitors from Natural Products.II. Active Components of a Paraguayan Crude Drug 'Para-parai mi,' Phyllanthus niruri. Chem. Pharm. Bull. 37(9): 2531-2532, 1989.
Antigingivitic 1,250 ug/ml
*
AntiHIV IC90=200 ug/ml
Tan, G.T., Pezzuto, J.M., Kinghorn,* A.D., Hughes, S.H. Evaluation Of Natural Products As Inhibitors Of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase. Journal of Natural Products, 54(1): 143-154, 1991.
Antimalarial IC50=0.5 uM
Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antioxidant 2/3 quercetin
*
Antioxidant >50 x tocopherol
Osawa, T. Phenolic Antioxidants in Dietary Plants as Antimutagens.Phenolic Compounds in Food and Their Effects on Health, Ch.11 p.142.
Antioxidant IC98=30 ppm
*
Antiperiodontic 1,250 ug/ml
*
Antiperoxidant IC50=29 uM
Planta Medica, 57: A54, 1991.
Antiplasmodial IC50=0.5 uM
Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antistreptococcic ID50=20 ug/ml
*
Antithyroid
Jim Duke's personal files.
Antiviral
Economic & Medicinal Plant Research, 5: 224.
Apoptotic
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Astringent
Martindale's 29th
Cancer-Preventive 3 ppm
*
Candida-SAP-Inhibitor IC50=8.4 uM
*
Cytotoxic 4.6 ug/ml
Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 359.
Deiodinase-Inhibitor
Jim Duke's personal files.
Glucosyl-Transferase-Inhibitor ID50=20 ug/ml
*
Hemostatic
Merck 11th Edition
Hepatoprotective IC55=30 ug/ml
Mayumi Ito (nee Someya), et al. 1990. Hepatoprotective Compounds from Canarium album and Euphorbia nematocypha. Chem. Pharm. Bull. 38(8): 2201-2203, 1990.
HIV-RT-Inhibitor
Economic & Medicinal Plant Research, 5: 224.
Juvabional
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Quinone-Reductase-Inducer 0.4 g/kg rat
Ahn, D., Putt, D., Kresty, L., Stoner, G. D., Fromm, D., Hollenberg, P. F. 1996. The Effects of Dietary Ellagic Acid on Rat Hepatic and Esophageal Mucosal Cytochromes P450 and Phase II Enzymes. Carcinogenesis, 17(4): 821-828.
Sunscreen 0.50%
Jim Duke's personal files.
Topoisomerase-I-Antagonist
Journal of Medicinal Food 2: 167.1999.
Xanthine-Oxidase-Inhibitor IC50=3.1 uM
Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
|
0
|
FAT
|
Seed |
-- |
83000.0 |
-0.96 |
* |
62
|
GALLIC-ACID
|
Flower |
-- |
-- |
-- |
* |
ACE-Inhibitor IC50=7.7 mM/l
*
Antiadenovirus
Economic & Medicinal Plant Research, 5: 194.
Antiallergenic
Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991.
Antianaphylactic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiasthmatic
Watt, J.M., and Breyer-Brandwijk, M.G. The Medicinal and Poisonous Plants of Southern and Eastern Africa. 1962.
Antibacterial MIC=1,000 ug/ml
*
Antibronchitic
Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991.
Antifibrinolytic
Economic & Medicinal Plant Research, 1: 53.
Antiflu
Economic & Medicinal Plant Research, 5: 194.
Antihepatotoxic
Okuda, T., Yoshida, T., and Hatano, T. Antioxidant Effects of Tannins and Related Polyphenols. Phenolic Compounds in Food and Their Effects on Health, Ch.7 p.93.
Antiherpetic EC50=>10 ug/ml
*
Antiinflammatory
Kroes, B.H., et al. 1991. Anti-Inflammatory Activity of Gallic Acid. Planta Medica, 58(6): 499.
Antileishmanic EC50=4.4 ug/ml
*
Antimutagenic
Economic & Medicinal Plant Research, 6: 235.
Antioxidant 7 x quercetin
*
Antioxidant IC44=33 ppm
*
Antiperiodontitic 10 ug/ml
*
Antiperoxidant IC50=69 uM
*
Antipolio
Economic & Medicinal Plant Research, 5: 194.
Antiproteolytic 10 ug/ml
*
Antiradicular 7 x quercetin
*
Antiradicular IC50=4.9 uM
*
Antiseptic
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antistaphylococcic MIC=1,000 ug/ml
*
Astringent
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Bacteristat
Lamikanra, A., Ogundaini, A.O., and Ogungbamila*, F.O. Antibacterial Constituents of Alchornea cordifolia Leaves. Phytotherapy Research 4(5): 198.
Bronchodilator
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choleretic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cyclooxygenase-Inhibitor
*
Floral-Inhibitor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Gram(+)icide MIC=1,000 ug/ml
*
Gram(-)icide MIC=1,000 ug/ml
*
Hepatoprotective
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Immunostimulant
McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Insulin-Sparing
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Myorelaxant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Nephrotoxic
Martindale's 29th
NO-Inhibitor IC-26=250 uM
*
Topoisomerase-I-Inhibitor
Hamada, S. I., Kataoka, T., Woo, J. T., Yamada, A., Yoshida, T., Nishimura, T., Otake, N., Nagai, K. 1997. Immunosuppressive Effects by Gallic Acid and Chebulagic Acid on CTL-Mediated Cytotoxicity. Biol Pharm Bull, 20: 1017-1019.
Xanthine-Oxidase-Inhibitor IC50=24 uM
Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
|
0
|
LACERACETAL
|
Leaf |
-- |
-- |
-- |
* |
0
|
LAGERINE
|
Plant |
-- |
-- |
-- |
* |
0
|
MALVIDIN-3-ARABINOSIDE
|
Plant |
-- |
-- |
-- |
* |
16
|
METHYL-GALLATE
|
Flower |
-- |
-- |
-- |
* |
Antiallergenic
Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991.
Antiasthmatic
Watt, J.M., and Breyer-Brandwijk, M.G. The Medicinal and Poisonous Plants of Southern and Eastern Africa. 1962.
Antibacterial MIC=12.5-400 ug/ml
*
Antibronchitic
Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991.
Antiherpetic
Economic & Medicinal Plant Research, 5: 207.
Antistaphylococcic MIC=200-400 ug/ml
*
Antiviral
Economic & Medicinal Plant Research, 5: 207.
Gram(+)icide MIC=200-400 ug/ml
*
Gram(-)icide MIC=12.5-50 ug/ml
*
Reverse-Transcriptase-Inhibitor
*
Xanthine-Oxidase-Inhibitor IC50=29 uM
Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
|
0
|
METHYLLAGERINE
|
Plant |
-- |
-- |
-- |
* |
0
|
PETUNIDIN-3-ARABINOSIDE
|
Plant |
-- |
-- |
-- |
* |
0
|
PROTEIN
|
Seed |
-- |
212000.0 |
-0.19 |
* |