Huperzia spp | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Cutleaf Clubmoss

How used

Medicinal

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Activities: 108

Chemicals w/Activities: 11

All Chemicals: 34

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# Activity	Chemical Name	Part	Low PPM	High PPM	StdDev	^*Reference
0	16-OXOLYCOCLAVINOL	Plant	--	--	--	*
0	16-OXOSERRATENETRIOL	Plant	--	--	--	*
0	4-HYDROXY-4-METHYL-GLUTAMIC-ACID	Plant	--	--	--	*
1	ACRIFOLINE	Plant	--	--	--	*
Toxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	ALKALOIDS	Plant	1000.0	9000.0	-0.19	*
0	ALPHA-OBSCURINE	Plant	--	--	--	*
2	ASPARAGINE	Plant	--	--	--	*
Antisickling Ekeke, G.I. and Shode, F.O. 1988. Phenylalanine is the Predominant Antisickling Agent in Cajanus cajan Seed Extract. Planta Medica 56(1): 41, 1990. Diuretic HerbalGram No. 17.
0	BETA-OBSCURINE	Plant	--	--	--	*
0	DEACETYLFAWCETTINE	Plant	--	--	--	*
61	FERULIC-ACID	Plant	--	--	--	*
Allelopathic Holappa, L.D., and Blum, U. 1991. Effects of Exogenously Applied Ferulic Acid, a Potential Allelopathic Compound, on Leaf Growth, Water Utilization, and Endogenous Abscisic Acid Levels of Tomato, Cucumber, and Bean. J. of Chemical Ecology, 17(5): 865. Analgesic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 69. Antiaggregant Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990. Antiallergic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antiarrhythmic Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticancer (Colon) * Anticancer (Forestomach) * Anticancer (Liver) * Anticancer (Skin) * Anticarcinogenic * Antidysmenorrheic * Antiestrogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiherpetic * Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. Antileukemic IC50=25-56 ug/ml Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18. Antineoplastic (Stomach) * Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18. Antioxidant 3,000 uM * Antioxidant 1/2 BHA * Antioxidant IC51=200 ppm * Antioxidant EC50=9-15 ug/ml * Antioxidant 1/3 quercetin * Antiradicular EC50=9-15 ug/ml * Antiradicular IC50=116-124 uM * Antiserotonin Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antithrombic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antitumor (Colon) * Antitumor (Forestomach) * Antitumor (Liver) * Antitumor (Skin) * Antitumor-Promoter IC46=10 uM Cancer Research, 48: 5941. Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Arteriodilator Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cardiac Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990. Cholagogue Pharmazie, 46: 156, 1991. Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Hepatoprotective Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Hepatotropic * Herbicide Angewandte Botanik 68(5/6)=1994. Page 195. Hydrocholerectic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hypolipidemic * Immunostimulant Economic & Medicinal Plant Research, 1: 124. Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994. Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25. Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. Pesticide * Phagocytotic * Preservative Merck 11th Edition Prostaglandigenic * Prostaglandin-Synthesis-Inhibitor 0.58-3.2 mM Xu, L. N., Yu, W. G., Tian, J. Y., Liu, Q. Y. 1990. Effect of Sodium Ferulate on Arachidonic Acid Metabolism. Yao Hsueh Hsueh Pao, 25(6): 412-416. Sunscreen Chemical Marketing Reporter; a weekly tabloid, 9/10/92. Uterosedative 30-100 mg/kg ivn rat Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
8	GLUTAMIC-ACID	Plant	--	--	--	*
Antialkali? 500-1,000 mg/day/orl/man Martindale's 29th Antiepileptic * Antihyperammonemic Martindale's 29th Antilithic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiprostatitic 125-250 mg 3 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiretardation Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anxiolytic Merck 11th Edition Neurotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
11	HUPERZINE-A	Plant	--	--	--	*
Antiacetylcholinesterase 2 mg/kg ims rat * Antiacetylcholinesterase IC50=0.1 uM * Antialzheimeran * Antiamnesic 0.25 mg/kg orl rat 8 day * Antiamnesic 0.1-0.125 mg/kg ipr mus * Antiamnesic 0.14-0.4 mg/kg iga mus * Antibutylcholinesterase IC50=58,895 nM/l * Anticholinesterase 3 x physostigmine * Antiglaucomic Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705. Antimyasthenic * Memorigenic *
3	HUPERZINE-B	Plant	--	--	--	*
Antialzheimeran * Anticholinesterase * Memorigenic *
2	LEUCINE	Plant	--	--	--	*
Antiencephalopathic Martindale's 29th Essential Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	LYCOBERGINE	Plant	--	--	--	*
0	LYCODOLINE	Plant	--	--	--	*
3	LYCOPODINE	Plant	--	--	--	*
Paralytic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Peristaltic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Uterocontractant Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
0	LYCOSERRAMINE	Plant	--	--	--	*
0	LYCOSERRINE	Plant	--	--	--	*
0	LYCOTHUINE	Plant	--	--	--	*

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Huperzia spp (Lycopodiaceae)

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