Chemical HUPERZINE-A | Dr. Duke's Phytochemical and Ethnobotanical Databases

Dr. Duke's Phytochemical and Ethnobotanical Databases

U.S. Department of Agriculture

Chemical ID

HUPERZINEA

Ubiquitous

No

List of known dosages
Dosage
LD50=3.8-7.2 mg/kg (iga mus)
LD50=1.6-2.2 mg/kg (ipr mus)
LD50=0.58-0.68 mg/kg (ivn mus)
LD50=2.2-4.1 mg/kg (scu mus)
LD50=23-29 mg/kg (iga rat)
LD50=4.2-5.9 mg/kg (ipr rat)
LD50=2.3-2.7 mg/kg (ivn rat)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Antiacetylcholinesterase	2 mg/kg ims rat	Duke, 1992 *
Antiacetylcholinesterase	IC50=0.1 uM	Duke, 1992 *
Antialzheimeran	not available	Duke, 1992 *
Antiamnesic	0.25 mg/kg orl rat 8 day	Duke, 1992 *
Antiamnesic	0.1-0.125 mg/kg ipr mus	Duke, 1992 *
Antiamnesic	0.14-0.4 mg/kg iga mus	Duke, 1992 *
Antibutylcholinesterase	IC50=58,895 nM/l	Duke, 1992 *
Anticholinesterase	3 x physostigmine	Duke, 1992 *
Antiglaucomic	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Antimyasthenic	not available	Duke, 1992 *
Memorigenic	not available	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Huperzia spp	Plant	not available	not available	not available	Duke, 1992 *
Lycopodium selago	Plant	not available	183.0	1.0	Duke, 1992 *
Lycopodium serratum	Plant	not available	0.2	-1.0	Duke, 1992 *