Euphorbia tirucalli | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Aveloz

How used

Medicinal

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Activities: 116

Chemicals w/Activities: 9

All Chemicals: 20

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
1	12-O-(2Z)(4E)-OCTADIENOYL-4-DEOXYPHORBOL-13-ACETATE	Latex Exudate	--	--	--	*
Irritant CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
0	3,3'-DI-O-METHYL-ELLAGIC-ACID	Stem	--	--	--	*
47	BETA-SITOSTEROL	Stem	--	--	--	*
Androgenic * Angiogenic * Anorexic Martindale's 28th Antiadenomic Merck 11th Edition Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Anticancer (Cervix) * Anticancer (Lung) * Antiedemic IC54=320 mg/kg orl * Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * Antileukemic * Antilymphomic * Antimutagenic 250 ug/ml * Antiophidic 2.3 mg mus Economic & Medicinal Plant Research, 5: 363. Antioxidant IC44=10 uM * Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antiprostaglandin 30 mg/day/12 wks * Antiprostatadenomic Merck 11th Edition Antiprostatitic 10-20 mg 3 x/day/orl man * Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Antitumor (Cervix) * Antitumor (Lung) * Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991. Apoptotic * Artemicide LC50=110 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Caspase-8-Inducer * Estrogenic * Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Hepatoprotective * Hypocholesterolemic 2-6 g/man/day/orl Martindale's 30th Hypocholesterolemic 9-3,330 mg/man/day/orl Martindale's 28th Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypolipidemic 2-6 g/day * Pesticide * Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Ulcerogenic 500 mg/kg ipr rat *
0	CAOUTCHOUC	Latex Exudate	28000.0	38000.0	-0.39	*
23	CITRIC-ACID	Plant	--	74000.0	2.00	*
Allergenic * Alpha-Amylase-Inhibitor * Antiaphthic 20,000 ppm Martindale's 28th Antiatherosclerotic * Antibacterial * Anticalculic * Anticoagulant Merck 11th Edition Antileishmanic * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antioxidant Synergist Merck 11th Edition Antiseborrheic * Antiseptic Martindale's 29th Antitubercular * Antitumor Economic & Medicinal Plant Research, 6: 235. Disinfectant Martindale's 29th FLavor FEMA 370-4,400 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hemostat * Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Laxative? Lawrence Review of Natural Products, Sep-91. Litholytic Martindale's 29th Mycobactericide * Odontolytic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Refrigerant Martindale's 28th
51	ELLAGIC-ACID	Stem	--	--	--	*
Abortifacient 1.2 mg/kg ivn mus * ACE-Inhibitor IC50=5 mM/l * Aldose-Reductase-Inhibitor IC50=0.2 ug/ml (strong activity) * Aldose-Reductase-Inhibitor IC50=0.2 uM * Antiaflatoxin * Antianaphylactic * Antibacterial ID50=20 ug/ml * Antibacterial 1,250 ug/ml * Anticancer (Cervix) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticancer (Colon) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticancer (Esophagus) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticancer (Mouth) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticariogenic ID50=20 ug/ml * Anticataract Shimizu, M., Horie, S., Terashima, S., Ueno, H., et al. 1989. Studies on Aldose Reductase Inhibitors from Natural Products.II. Active Components of a Paraguayan Crude Drug 'Para-parai mi,' Phyllanthus niruri. Chem. Pharm. Bull. 37(9): 2531-2532, 1989. Antigingivitic 1,250 ug/ml * AntiGTF ID50=20 ug/ml * AntiHIV IC90=200 ug/ml Tan, G.T., Pezzuto, J.M., Kinghorn,* A.D., Hughes, S.H. Evaluation Of Natural Products As Inhibitors Of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase. Journal of Natural Products, 54(1): 143-154, 1991. Antihyperthyroid * Antiinflammatory * Antimalarial IC50=0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antimutagenic * Antioxidant 2/3 quercetin * Antioxidant >50 x tocopherol Osawa, T. Phenolic Antioxidants in Dietary Plants as Antimutagens.Phenolic Compounds in Food and Their Effects on Health, Ch.11 p.142. Antioxidant IC98=30 ppm * Antiperiodontic 1,250 ug/ml * Antiperoxidant IC50=29 uM Planta Medica, 57: A54, 1991. Antiplaque 1,250 ug/ml * Antiplasmodial IC50=0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antiseptic 1,250 ug/ml * Antistreptococcic ID50=20 ug/ml * Antithyroid Jim Duke's personal files. Antitumor * Antiviral Economic & Medicinal Plant Research, 5: 224. Antiyeast IC50=10.5 uM * Apoptotic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Astringent Martindale's 29th Cancer-Preventive 3 ppm * Candida-SAP-Inhibitor IC50=8.4 uM * Cytotoxic 4.6 ug/ml Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 359. Deiodinase-Inhibitor Jim Duke's personal files. Detoxicant * Glucosyl-Transferase-Inhibitor ID50=20 ug/ml * Hemostatic Merck 11th Edition Hepatoprotective IC55=30 ug/ml Mayumi Ito (nee Someya), et al. 1990. Hepatoprotective Compounds from Canarium album and Euphorbia nematocypha. Chem. Pharm. Bull. 38(8): 2201-2203, 1990. HIV-RT-Inhibitor Economic & Medicinal Plant Research, 5: 224. Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Pesticide * Quinone-Reductase-Inducer 0.4 g/kg rat Ahn, D., Putt, D., Kresty, L., Stoner, G. D., Fromm, D., Hollenberg, P. F. 1996. The Effects of Dietary Ellagic Acid on Rat Hepatic and Esophageal Mucosal Cytochromes P450 and Phase II Enzymes. Carcinogenesis, 17(4): 821-828. Sunscreen 0.50% Jim Duke's personal files. Topoisomerase-I-Antagonist Journal of Medicinal Food 2: 167.1999. Xanthine-Oxidase-Inhibitor IC50=3.1 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
1	EUPHOL	Latex Exudate	--	--	--	*
Abortifacient Singla*, A.K. Pathak, K. 1989. Phytoconstituents of Euphorbia species. Fitoterapia 61(6): 483-508, 1990.
0	EUPHORONE	Latex Exudate	--	--	--	*
7	GLUCOSE	Plant	--	--	--	*
Acetylcholinergic * Antiedemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antihepatotoxic Merck 11th Edition Antiketotic Merck 11th Edition Antivaricose Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hyperglycemic Merck 11th Edition Memory-Enhancer Science News, 138: 189, 1990.
0	HENTRIACONTANE	Stem	--	--	--	*
0	HENTRIACONTANOL	Stem	--	--	--	*
0	ISOEUPHORAL	Latex Exudate	--	--	--	*
0	KAMEPFEROL	Plant	--	--	--	*
15	MALIC-ACID	Plant	--	--	--	*
Antiatherosclerotic * Antibacterial * Antifibromyalgic 300 mg 3x/day * Antioxidant Synergist Merck 11th Edition Antiseborrheic * Antiseptic Martindale's 29th Antitubercular * Antitumor Economic & Medicinal Plant Research, 6: 235. Bacteristat * Bruchiphobe Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Hemopoietic * Laxative? Lawrence Review of Natural Products, Sep-91. Mycobactericide * Pesticide * Sialogogue Martindale's 29th
0	RESIN	Latex Exudate	--	--	--	*
0	SAPOGENIN-ACETATES	Plant	--	1000.0	--	*
7	SUCCINIC-ACID	Plant	--	--	--	*
Additive FEMA 200-2,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Antifeedant * Bruchiphobe Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Dye Merck 11th Edition Perfumery Merck 11th Edition Pesticide *
2	TARAXASTEROL	Latex Exudate	--	--	--	*
Antiedemic * Antiinflammatory 1/2 indomethacin *
0	TARAXERIN	Stem	--	--	--	*
0	TIRUCALLOL	Latex Exudate	--	--	--	*

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Euphorbia tirucalli (Euphorbiaceae)

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