Echinacea spp | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Coneflower, Echinacea

How used

Medicinal

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Activities: 609

Chemicals w/Activities: 64

All Chemicals: 129

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	(+)-TARTARIC-ACID	Plant	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	(E)-10-HYDROXY-4,10-DIMETHYL-4,11-DODECADIEN-2-ONE	Plant	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	13-HYDROXYOCTADECA-(9Z,11E,15Z)-TRIENOIC-ACID	Shoot	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	2,3-O-DIFERULOYLTARTARIC-ACID	Leaf	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	2-METHYLTETRADECA-5,12-DIENE	Plant	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	2-METHYLTETRADECA-6,12-DIENE	Plant	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	2-O-CAFFEOYL-3-(5-(ALPHA-CARBOXY-BETA-(3,4,-DIHYDROXYPHENYL...	Plant	--	--	--	*
0	2-O-CAFFEOYL-3-O-CUMAROYLTARTARIC-ACID	Shoot	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	2-O-CAFFEOYL-3-O-FERULOYLTARTARIC-ACID	Leaf	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	2-O-CAFFEOYLTARTARIC-ACID	Leaf	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	2-O-FERULOYLTARTARIC-ACID	Leaf	--	--	--	Economic & Medicinal Plant Research, 5: 253.
3	3,5-DICAFFEOYL-QUINIC-ACID	Plant	--	--	--	Economic & Medicinal Plant Research, 5: 253.
Antihemolytic 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antioxidant 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antiradicular 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
0	4,5-O-DICAFFEOYLQUINIC-ACID	Plant	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	6-O-CAFFEOYLECHINACOSIDE	Root	--	--	--	Economic & Medicinal Plant Research, 5: 253.
0	ALKYLAMIDES	Root	40.0	1510.0	--	Economic & Medicinal Plant Research, 5: 253.
28	ALPHA-PINENE	Fruit	--	--	--	Economic & Medicinal Plant Research, 5: 253.
Allelochemic * Allergenic * Antiacne * Antibacterial * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory 500 mg/kg * Antipneumonic * Antiseptic * Antispasmodic * Antistaphylococcic * Antiviral Economic & Medicinal Plant Research, 5: 195. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Coleoptophile * Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. FLavor FEMA 15-150 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide IC50=30 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insecticide 0.82 uM/fly * Insectifuge 50 ppm * Insectiphile J. Stored. Prod. Res., 22:141, 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. P450-2B1-Inhibitor IC50=0.087 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Sedative Lawrence Review of Natural Products, Jun-90. Spasmogenic * Tranquilizer Lawrence Review of Natural Products, Jun-90. Transdermal *
5	ALUMINUM	Root	786.0	12900.0	6.61	Economic & Medicinal Plant Research, 5: 253.
Antisilicotic Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. Antivaginitic Martindale's 28th Candidicide Martindale's 28th Encephalopathic Martindale's 29th Pesticide *
101	APIGENIN	Leaf	--	--	--	Economic & Medicinal Plant Research, 5: 253.
11B-HSD-Inhibitor * AntiADD * Antiaflatoxin IC50=9.52 uM * Antiaflatoxin IC50=2.57 ppm * Antiaggregant * Antiaging * Antiallergic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiangiogenic 4 uM * Antiarrhythmic * Antibacterial Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125. Anticancer (Lung) * Anticomplementary * Antidermatitic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Antiestrogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiherpetic 20-54 ug/ml * Antihistaminic IC50=10-35 uM * AntiHIV IC50=143 ug/ml * AntiHIV IC72=200 ug/ml * Antiinflammatory #NAME? * Antiinflammatory IC~65=1,000 uM * Antileukemic 20-50 uM * Antimelanomic 1-50 uM * Antimetastatic 1-50 uM * Antimutagenic ID50=0.55 ug/ml * Antimutagenic ID50=10-40 nM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Antioxidant IC28.5=62.5 ug/ml * Antioxidant 1.5 x Vit. E * Antiperistaltic * Antiproliferant 1-50 uM * Antiproliferant IC50=155 uM * Antispasmodic EC50=1-5 uM * Antistress 10 mg/kg * Antithyroid Jim Duke's personal files. Antitumor 1-50 uM * Antitumor (Breast) 1-50 uM * Antitumor (Lung) * Antitumor (Skin) * Antiviral 20-54 ug/ml * Anxiolytic 10 mg/kg * Apoptotic 12-60 uM * Aromatase-Inhibitor IC65=1 uM/l Journal of Medicinal Food 2: 235.1999. Beta-Glucuronidase-Inhibitor IC50=~40 uM * Calcium-Antagonist? Biochimica & Biophysica Acta, 1115: 69, 1991. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Choleretic * CNS-Depressant * COX-1-Inhibitor IC65=1,000 uM * COX-2-Inhibitor IC50=<15 uM * COX-2-Inhibitor <40 uM * COX-2-Inhibitor IC>65=1,000 uM * Cyclooxygenase-Inhibitor * Cytochrome-P450-1A1-Inhibitor * Cytotoxic IC88=10 ug/ml Planta Medica, 57: A113, 1991. Cytotoxic IC50=9.5 uM * Cytotoxic 1-50 uM * Deiodinase-Inhibitor Jim Duke's personal files. Differentiator IC40=40 uM * Differentiator MIC=30 uM * Diuretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. DNA-Protective * Estrogenic 16% genistein * Estrogenic EC50=0.1-25 uM/l Journal of Medicinal Food 2: 227.1999. Estrogenic EC50=1 uM * HIF-1alpha-Inhibitor * Hyaluronidase-Inhibitor IC50+=50-250 uM * Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. ICAM-1-Inhibitor * IKK-Inhibitor * iNOS-Inhibitor IC50=<15 uM * Inotropic * Interleukin-6-Inhibitor * MAO-Inhibitor * MAPK-Inhibitor * Musculotropic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Mutagenic * Myorelaxant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. NADH-Oxidase-Inhibitor * NF-kB-Inhibitor * NO-Synthase-Inhibitor 5-50 uM * Nodulation-Signal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Ornithine-Decarboxylase-Inhibitor * P21-Inducer 10-70 uM * Pesticide * PKC-Inhibitor IC50=10 uM * Polyamine-Synthesis-Inhibitor * Progestational * Protein-Kinase-C-Inhibitor IC50=10-40 uM * PTK-Inhibitor 10-100 uM * Quinone-Reductase-Inducer 20 uM Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216. Radioprotective * Sedative 30-100 mg/kg * Sunscreen * TNF-alpha-Inhibitor IC50=3.27 uM * Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237. Topoisomerase-II-Inhibitor IC28=18 uM * Topoisomerase-II-Inhibitor IC45=180 uM * Topoisomerase-II-Inhibitor 50 ug/ml Azuma, Y., Onishi, Y., Sato, Y., Kizaki, H. 1995. Effects of Protein Tyrosine Kinase Inhibitors With Different Modes of Action on Topoisomerase Activity and Death of IL-2-Dependent CTLL-2-Cells. J Biochemistry, 118: 312-318. Uterotrophic EC50=0.1-25 uM/l Journal of Medicinal Food 2: 227.1999. Vasodilator * VEGF-Inhibitor IC50=2-7 uM * Xanthine-Oxidase-Inhibitor 0.36 uM *
6	ARABINOGALACTAN	Root	--	--	--	Pedersen, M. 1987. Nutritional Herbology. Pederson Publishing. Bountiful, Utah. 377 pp.
Anticomplementary * Antileishmanic 250 ug/ml * Immunostimulant 3.7-500 ug/ml * Interferonogenic 3.7-500 ug/ml * Mitogenic * Phagocytotic *
112	ASCORBIC-ACID	Leaf	--	2140.0	-0.25	Economic & Medicinal Plant Research, 5: 253.
Acidulant FEMA 6,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Aldose-Reductase-Inhibitor Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Analgesic 5-10 g/day * Angiotensin-Receptor-Blocker * AntiAGE 2,000 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaggregant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaging 400 mg/day * Antiallergic * Antialzheimeran 2,000-6,000 mg/day * Antiarthritic 0.2-1 g/day * Antiasthmatic 1,000 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiatherosclerotic * Antibacterial Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anticataract 1 g 3x/day * Anticataract 350 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticataract 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Anticervicaldysplasic 1,000-2,000 mg/day * AntiCFS 500-1,000 mg * Anticlimacteric 500-5,000 mg/day * Anticold 1-2 g/man/day * AntiCrohn's 50-100 mg/day/orl/man Martindale's 29th AntiCTS 1,000 mg 3x/day * Antidecubitic 500 mg/man/2x/day Martindale's 28th Antidementia * Antidepressant 2,000 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antidiabetic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antidote (Aluminum) Economic & Medicinal Plant Research, 6: 189. Antidote (Cadmium) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Paraquat) Martindale's 28th Antieczemic 3.5-5 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiedemic 1 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiencephalitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiendometriotic 2,000 mg/day * Antifatigue 500-1,000 mg * Antifibrotic 1,000-2,000 mg * Antigallstone 1,000-3,000 mg/day * Antigastritic * Antigingivitic * Antiglaucomic 2 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antihangover 1,000 mg * Antihemorrhagic 1 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihepatitic 2-6 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihepatotoxic Economic & Medicinal Plant Research, 6: 189. Antiherpetic 1-5 g/day * Antihistaminic 2 g/day orl man * Antihypertensive * Antiinfertility 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiinflammatory Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antilepric 1.5 g/man/day Martindale's 28th Antilithic 1,000-3,000 mg/day * AntiLyme 500-2,000 mg * Antimaculitic * Antimeasles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 500-5,000 mg/day * Antimigraine Martindale's 29th Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antineuramidase * Antinitrosic 1 g/man/day Martindale's 28th Antiobesity 1 g 3x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiorchitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiosteoarthritic 1 g 2x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic 500 mg/day * Antioxidant 100 ppm * Antiparkinsonian 1 g 2-3x/day * Antiparotitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiperiodontitic 1 g 2x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antipneumonic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antipodriac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antipoliomyelitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antipyretic Economic & Medicinal Plant Research, 6: 189. Antiradicular Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 AntiRaynaud's 500 mg 1-2x/day * Antiretinotic * Antirheumatic * Antirhinitic 1,000 mg 3x/day * Antiscorbutic 10 mg/man/day Martindale's 28th Antiseptic 4-8 g/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiseptic MIC=3.3-217 mg/ml Martindale's 28th Antishingles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antispasmodic 500-5,000 mg/day * Antistress 500-1,000 mg * Antisyndrome-X 1-4 g/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antitumor (Gastric) * Antitumor (Lung) * Antiulcer * Antiviral 1-5 g/day * Apoptotic 1-10 mM * Asthma-preventive 1,000 mg/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Beta-Adrenergic Receptor Blocker * Beta-Glucuronidase-Inhibitor 1.5 g/day/man * Calcium-Antagonist * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective * Cold-preventive 1-2 g/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Collagenic * Detoxicant * Diuretic 700 mg/man/orl * Fistula-Preventive Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Hypocholesterolemic 300-1,000 mg/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Hypoglycemic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypotensive 1,000 mg/man/day * Immunomodulator * Immunostimulant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Interferonogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Lithogenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Mucolytic 1 g/woman/day Martindale's 28th Pesticide * Uricosuric 4 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Urinary-Acidulant Martindale's 29th Vasodilator * Vulnerary Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Echinacea spp (Asteraceae)

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